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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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12981
Economic and public health impact of decentralized HIV viral load testing: A modelling study in Kenya
Published 2019“…The GeneXpert system is a diagnostic point-of-care technology that can quantify, amongst others, HIV VL. …”
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12982
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12983
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12984
Depletion of Hth and Exd in the IPCs results in phenotypes associated with reduced systemic insulin signalling.
Published 2022“…(G) IPC-specific depletion of hth or exd resulted in decreased female fecundity. Every data point is the average (4–5 females per vial) cumulative number of eggs layed for 14 days (one-way ANOVA with post-hoc Dunnett’s test comparing to <i>mCherry</i><sup><i>RNAi</i></sup> controls * p <0.05,** p<0.01).…”
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12985
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12986
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12987
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12988
Docking results of effective compounds in TFDM.
Published 2023“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”
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12989
Active compounds screened from TFDM.
Published 2023“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”
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12990
Network of compound-target-pathway.
Published 2023“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”
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12991
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12992
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12993
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12994
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12995
Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines
Published 2017“…Inhibitory concentrations to achieve 50% cell death (IC<sub>50</sub>) were determined for BT and paclitaxel in each cell line. …”
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12996
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12997
Biological effects of ultrashort electric pulses in a neuroblastoma cell line: the energy density role
Published 2021“…<p>Despite the numerous literature results about biological effects of electromagnetic field (EMF) exposure, the interaction mechanisms of these fields with organisms are still a matter of debate. Extremely low frequency (ELF) MFs can modulate redox homeostasis and we showed that 24 h exposure to 50 Hz–1 mT has a pro-oxidant effect and effects on the epigenome of SH-SY5Y cells, decreasing miR-34b/c expression through the hypermethylation of their promoter.…”
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12998
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12999
UBKIs possess broad antiviral activity, are effective in primary cells, and impose a barrier against resistance development.
Published 2019“…The calculation of p-values revealed a significant decrease of log-transformed virus-titers in the regorafenib and sorafenib-treated groups relative to the DMSO control at the indicated time points: *: p-value ≤ 0.05. …”
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13000