Discovery of Novel Thiophene-Based Baloxavir Derivatives as Potent Cap-Dependent Endonuclease Inhibitors for Influenza Treatment by Yongzhi Chen (172975)

“…Among them, <b>ATV2301</b> exhibited an excellent anti-influenza activity (EC₅₀, H1N1 = 1.88 nM, H3N2 = 4.77 nM), a higher safety index (SI, H1N1 = 18218, H3N2 = 7180), and a remarkably improved oral bioavailability (<i>F</i> = 71.60%). …”

Supplemental figure S3 from Movements and residency of Caribbean reef sharks at a remote atoll in Belize, Central America by Ivy E. Baremore (11204064)

Pharmacologic suppression of GABA_A receptor function differentially affects sleep in control and GEFS+ flies. by Emily Petruccelli (794164)

Confirmation of berberine by FTIR and NMR. by Hammad Ismail (4227988)

Fig 5 - by Katharina Riebenbauer (10726250)

Climate and seed size of a dry forest species: influence on seed production, physiological quality, and tolerance to abiotic stresses by Samara Elizabeth Vieira Gomes (4718994)

“…The predicted increase in temperature will not impair germination, however, the time available for seedling establishment will decrease due to lacking rainfall. The increase in the amount of small-sized seeds produced in drought years is a strategy for coping with harsh environments, rather than a decrease in seed quality.…”

Image_1_A large-scale forward genetic screen for maize mutants with altered lignocellulosic properties.tiff by Shaogan Wang (14727736)

Exploring reopening strategies for low disease transmission <i>v</i>_<i>r</i> with testing capacity. by Mackenzie Dalton (14093874)

<i>malayi</i> N-AChR requires additional accessory proteins and has unchanged pharmacology compared to other clade III N-AChR. by Jennifer D. Noonan (14117157)

Experiment procedures. by Hui-Ya Chen (13919141)

Data Sheet 1_Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection.docx by Ping-Chang Lin (2848379)

“…</p>Results<p>In this study, post-treatment with HSE resulted in dose-dependent decreases in both the RNA levels and TCID₅₀ of SARS-CoV-2 in Vero E6 cells; treatment with 50 μg/ml and 100 μg/ml alcohol HSEs achieved up to 95.323% and 92.587% inhibition, respectively. …”

Supplementary Material for: Use of Liraglutide 3.0 mg for Weight Management in a Real-World Setting in Switzerland by Haase C.L. (11305977)

“…Median maximum dose received was 1.5 mg, and 13.7% of patients reached the maintenance dose of 3.0 mg. Mean 7-month weight change from baseline in the full cohort was −4.1 kg (95% confidence interval: −5.0, −3.2; <i>p</i> < 0.001; −4.2%). …”

Erratum: Development and Validation of a New Dry Weight Estimation Method Using Single Frequency Bioimpedance in Hemodialysis Patients by Dou Y. (4272337)

“…<i>Methods:</i> We hypothesized that the change in whole body resistance at 50 kHz (R₅₀) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. …”

Ab-specific variations in neutralization potency against HIV-1 strains assigned to different neutralization tiers. by Caio Foulkes (20592250)

Data_Sheet_1_Global Patterns and Drivers of Litter Decomposition Under Nitrogen Enrichment: A Meta-Analysis.docx by Yuan Su (169075)

“…However, litter decomposition was significantly influenced by the level of N addition in plantations and secondary forests, with an increase in litter mass loss at low N addition (50 kg N ha^–1 year^–1) and a decrease in litter mass loss at high N addition (>50 kg N ha^–1 year^–1). …”

DataSheet_1_CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma.docx by Jiancheng Lv (464636)

“…</p>Results<p>We discovered that the levels of circFAM114A2 were decreased in urothelial carcinoma cell lines and tissues. …”

Table_1_A Time-Dose Response Model to Assess Diuron-Induced Photosynthesis Inhibition in Freshwater Biofilms.DOCX by Soizic Morin (597578)

“…We found a rapid decrease in photosynthetic efficiency: t_1/2 values were dose-dependent and ranged from < 30 s (highest concentration of exposure) to 7′20^′′ (lowest concentration). …”

Symptoms self-reported and/or documented in the electronic health record during the acute COVID-19 illness, by hospitalization status and age group. by Chelsea S. Lutz (16001569)

The in-vitro drug assay against the trophozoites and cysts of <i>Acanthamoeba</i>. by Alireza Latifi (14593561)

The generalized neutralization sensitivity phenotype is equivalent in different assay formats. by Caio Foulkes (20592250)