Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1 by Brigitte M. Krenn (225315)

“…The H5N1 reassortants containing the indicated mutation displayed an increased resistance to acidic pH and high temperature treatment compared to those lacking modification. The mutation ensured a higher viral uptake as shown by immunohistochemistry in the respiratory tract of mice and 25 times lower mouse infectious dose₅₀. …”

DataSheet_1_Trapped in a Glass Bell Jar: Neural Correlates of Depersonalization and Derealization in Subjects at Clinical High-Risk of Psychosis and Depersonalization–Derealization... by Jessica R. Büetiger (9364703)

“…Investigating two separate DP/DR populations with an identical neuroimaging technique, our study also indicates that there may be divergent pathophysiological mechanisms—decreased neuronal activity in the orbitofrontal cortex, but increased activity within the caudate nucleus—leading to a final common pathway with similar psychopathological symptoms. …”

Data_Sheet_1_Combined 5-Fluorouracil and Low Molecular Weight Heparin for the Prevention of Postoperative Proliferative Vitreoretinopathy in Patients With Retinal Detachment: A Met... by Chen Chen (6544)

“…</p><p>Results: Six clinical trials with a total of 1,208 participants were included. We found that combined 5-FU and LMWH infusion did not improve the primary success of vitrectomy at 6 months (RR = 1.00, 95% CI = 0.95, 1.07, P = 0.89, I² = 50%). …”

Data_Sheet_4_Combined 5-Fluorouracil and Low Molecular Weight Heparin for the Prevention of Postoperative Proliferative Vitreoretinopathy in Patients With Retinal Detachment: A Met... by Chen Chen (6544)

“…</p><p>Results: Six clinical trials with a total of 1,208 participants were included. We found that combined 5-FU and LMWH infusion did not improve the primary success of vitrectomy at 6 months (RR = 1.00, 95% CI = 0.95, 1.07, P = 0.89, I² = 50%). …”

Data_Sheet_3_Combined 5-Fluorouracil and Low Molecular Weight Heparin for the Prevention of Postoperative Proliferative Vitreoretinopathy in Patients With Retinal Detachment: A Met... by Chen Chen (6544)

“…</p><p>Results: Six clinical trials with a total of 1,208 participants were included. We found that combined 5-FU and LMWH infusion did not improve the primary success of vitrectomy at 6 months (RR = 1.00, 95% CI = 0.95, 1.07, P = 0.89, I² = 50%). …”

Direct recruitment of polarity factors to the patch enables highly mobile clusters. by Samuel A. Ramirez (4951921)

“…<b>(C)</b> Patch diffusivities as a function of total GEF for simulations where <i>k</i>_<i>2b</i> has been decreased by a factor of 1/16 and <i>k</i>_<i>5a</i> has been increased by a factor of 10 relative to the parameters in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008525#pcbi.1008525.t001" target="_blank">Table 1</a>. …”

Meta-analyses of COVIDST diagnostic accuracy. by Apoorva Anand (17921197)

“…Highest sensitivities were reported for: a) symptomatic individuals (73.91%, 95%CI: 68.41–78.75%; n = 9), b) mid-turbinate nasal samples (77.79%, 95%CI: 56.03–90.59%; n = 14), c) supervised strategy (86.67%, 95%CI: 59.64–96.62%; n = 13), and d) use of digital interventions (70.15%, 95%CI: 50.18–84.63%; n = 14). …”

Video_1_Use of pressure muscle index to predict the contribution of patient’s inspiratory effort during pressure support ventilation: a prospective physiological study.MP4 by Ran Gao (469211)

“…As targeted PMI increased, pressure support settings decreased significantly from a median (interquartile range) of 11 (10–12) to 5 (4–6) cm H₂O (p < 0.001), which resulted in a significant increase in pressure–time products of respiratory muscle [from 2.9 (2.1–5.0) to 6.8 (5.3–8.1) cm H₂O•s] and the fraction of pressure generated by the patient [from 25% (19–31%) to 72% (62–87%)] (p < 0.001). …”

Chemical Properties of Cationic Phenylplatinum(II) Complexes with a 2,2‘-Bipyridine Ligand. Insertion of CO and Allene into the Pt−C Bond and Oxidative Addition of MeI by Takeyoshi Yagyu (2381218)

“…<b>1-MeCN</b> reacts with MeI at 50 °C to produce a mixture of two isomeric cationic Pt(IV) complexes after 9 days. …”

Gene Content of the Differentially Hybridizing Virulence Loci between <i>B. bronchiseptica</i> Complex I and IV, as Determined by CGH by Dimitri A Diavatopoulos (274876)

“…The BP probe of <i>tcfA</i> was 100% similar to <i>B. pertussis</i> Tohama and 85.1% similar to <i>B. bronchiseptica</i> RB50. …”

Table 1_COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023).xls by Xiaoqiang Li (612879)

“…The MIC values for vancomycin in MRSA strains remained stable over time, whereas a decreasing susceptibility trend to vancomycin in MSSA strains and linezolid MIC shifts were not observed. …”

Sequence conservation and coverage analysis, predicted accuracy of models, and prediction of metal-binding residues of ZepA from <i>Anabaena</i> and <i>Lacipirellula limnantheis</i... by Cristina Sarasa-Buisan (12627973)

“…In the 5 models, accuracy decreased between 30 and 70 at the 10 N-terminal amino acids (pLDDT < 50) predicting a disordered region (unstructured under physiological conditions). …”

Effect of miRNAs on wound healing. by Vincent A. Funari (255249)

MiR-150 expression promotes myeloid differentiation of CD34+ PBMCs from healthy donors. by Valerie A. Morris (462679)

“…<p>Primary CD34+ PBMCs were transduced with pre-miR-150 or empty control lentiviral (ECV) supernatants, sorted for GFP expression, and then assayed by flow cytometry for CD11b, CD34, and CD14 expression or colony formation by colony-forming unit (CFU) assays. (A) Cells were assessed by flow cytometry at the indicated days after cell transduction cultured in the presence of rhSCF, rhIL3, rhIL6, rhGCSF, rhGMCSF (50 ng/ml each), and EPO (2 U/ml). …”

Starvation reduces copper avoidance. by Molly A. Matty (6432926)

“…E) Animals are exposed to decreasing concentrations of diacetyl (DiA) (0.2%, 0.1% and 0.05%, or 1:200, 1:1000, and 1:2000, respectively) and other volatile attractants 0.1% Benzaldehyde (BZ) and 0.05% Isoamyl Alcohol (IAA). 50 mM CuSO₄ is the repellant in each condition N≥6. …”

Gene expression of <i>Vegf-A</i> and <i>Mcp-1</i> by qRT-PCR at the outflow vein of AVF three days after fistula placement in <i>Iex-1</i> KO and WT mice. by Akshaar Brahmbhatt (551498)

Myocardial adaption to HI(R)T in previously untrained men with a randomized, longitudinal cardiac MR imaging study (Physical adaptions in Untrained on Strength and Heart trial, PUS... by Michael Scharf (707497)

“…Indexed LV (48.4±11.1 to 50.8±11.0 ml/m²) and RV (48.5±11.0 to 50.6±10.7 ml/m²) stroke volume significantly increased with HI(R)T (p<0.001). …”

PCNA stimulates SsoXPF nuclease activity on biotin–streptavidin end-blocked DNA substrates by Jennifer A. Roberts (12859)

“…All rights reserved</p> () A 50 nt oligonucleotide (b50-bio) with biotin-dT nucleotides at positions 3 and 45 was annealed to a complementary 25 nt oligonucleotide (x26–50) to make a 3′-overhang substrate. …”

Relationship between system (animal) compliance, animal size, and maximum adhesive force. by Casey A. Gilman (791467)

Thermostability (T₉₀) and half-life of infectivity decay at 37°C (t_1/2) of select HIV-1 (PSVs) from clades A, B and C. by Nitish Agrawal (105325)

“…</p>3<p>t_1/2, the time (in hours) at which HIV-1 infectivity decreases by 50% under physiological conditions (37°C), and the standard error of the mean (SEM) of at least three independent experiments.…”