DataSheet6_A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells.ZIP by Xing-Hui Song (11665903)

“…Among them, 67 circRNAs exhibited divergent expression between the two groups (fold change ≥2, p ≤ 0.05), of which 33 were upregulated (49.3%) and 34 were downregulated (50.7%). The proliferation of circ-ATXN2-overexpressing cells decreased significantly in vitro, which was further validated by xCELLigence real-time cell analysis, EdU staining, and cell cycle assay. …”

Data_Sheet_1_Anemia is independently associated with mortality in people living with human immunodeficiency virus/acquired immune deficiency syndrome: A propensity score matching-b... by Meihua Jin (787887)

“…Meanwhile, the AHR tended to increase by 85% on average (AHR = 1.85, 95% CI: 1.37–2.50; p < 0.001) with a per standard deviation (SD) decrease in plasma hemoglobin. …”

Table1_Safety and possible anti-inflammatory effect of paclitaxel associated with LDL-like nanoparticles (LDE) in patients with chronic coronary artery disease: a double-blind, pla... by Lucas Lage Marinho (17999740)

“…From the baseline to the end of follow-up, there was a non-significant trend toward a decrease in IL-6 levels and hsCRP in the LDE-paclitaxel group (−16% and −28%, respectively), not observed in placebo. …”

Data Sheet 1_Associations between high-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and their ratio with metabolic dysfunction-associated steatotic li... by Hong Chen (108084)

“…Kaplan–Meier analysis, Cox proportional hazards models, restricted cubic splines (RCS), sensitivity analyses, and receiver operating characteristic (ROC) curves were employed to evaluate associations between NHHR, non-HDL-C, HDL-C, and new-onset MASLD and compare predictive performance across lipid parameters.</p>Results<p>A total of 36,897 participants (mean age 42.1 years; 56.5% female) were followed for a mean of 3.19 years, with 20.3% developing new-onset MASLD. …”

Data Sheet 2_Associations between high-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and their ratio with metabolic dysfunction-associated steatotic li... by Hong Chen (108084)

“…Kaplan–Meier analysis, Cox proportional hazards models, restricted cubic splines (RCS), sensitivity analyses, and receiver operating characteristic (ROC) curves were employed to evaluate associations between NHHR, non-HDL-C, HDL-C, and new-onset MASLD and compare predictive performance across lipid parameters.</p>Results<p>A total of 36,897 participants (mean age 42.1 years; 56.5% female) were followed for a mean of 3.19 years, with 20.3% developing new-onset MASLD. …”

Data_Sheet_1_Early prediction of pathological response to neoadjuvant chemotherapy of breast tumors: a comparative study using amide proton transfer-weighted, diffusion weighted an... by Nan Zhang (46264)

“…Group 1 included patients with a greater degree of decrease in major histologic responder (MHR, Miller-Payne G4-5), while group 2 included non-MHR cases (Miller-Payne G1-3). …”

Gene expression of <i>Iex-1</i> and <i>Vegf-A</i> by qRT-PCR in outflow vein of AVF seven days after adventitial delivery of hydrogel alone, hydrogel with nanoparticle PLGA without... by Akshaar Brahmbhatt (551498)

Data_Sheet_1_Aspergillus terreus (Trichocomaceae): A Natural, Eco-Friendly Mycoinsecticide for Control of Malaria, Filariasis, Dengue Vectors and Its Toxicity Assessment Against an... by C. Ragavendran (6006917)

“…The results of the biochemical analysis indicated that a decrease in the level of acetylcholinesterase, α-carboxylesterase, and β-carboxylesterase in extract treated fourth instar larvae of all tested mosquito species. …”

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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Table_1_Occurrence and Severity of Catheter-Related Bladder Discomfort of General Anesthesia Plus Epidural Anesthesia vs. General Anesthesia in Abdominal Operation With Urinary Cat... by Shunxiang Sun (11388317)

“…Meanwhile, subgroup analyses showed that the reduction of occurrence and severity of CRBD in GA + EA group compared to GA group was more obvious in male patients and patients ≥50 years. Besides, SBP at 0, 0.5, 1, and 3 h, as well as DBP at 0, 0.5, and 3 h were all decreased in GA + EA group compared to GA group (all P < 0.05), while HR was increased at 0 h in GA + EA group compared to GA group (P = 0.034). …”

Table_2_Occurrence and Severity of Catheter-Related Bladder Discomfort of General Anesthesia Plus Epidural Anesthesia vs. General Anesthesia in Abdominal Operation With Urinary Cat... by Shunxiang Sun (11388317)

“…Meanwhile, subgroup analyses showed that the reduction of occurrence and severity of CRBD in GA + EA group compared to GA group was more obvious in male patients and patients ≥50 years. Besides, SBP at 0, 0.5, 1, and 3 h, as well as DBP at 0, 0.5, and 3 h were all decreased in GA + EA group compared to GA group (all P < 0.05), while HR was increased at 0 h in GA + EA group compared to GA group (P = 0.034). …”

Table_1_Correlation between ratio of fasting blood glucose to high density lipoprotein cholesterol in serum and non-alcoholic fatty liver disease in American adults: a population b... by Xianjing Jin (19535434)

“…According to the subgroup analysis, the correlation was stronger in other race, participants at the age <50 years old and those with non-diabetes. In this study, a non-linear relationship and saturation effect between GHR and the prevalence of NAFLD was also revealed, characterized by an inverted L-shaped curve, with an inflection point of 7.443. …”

Supplementary Material for: G-8 Geriatric Screening Tool Independently Predicts Progression-Free Survival in Older Ovarian Cancer Patients Irrespective of Maximal Surgical Effort:... by Anic K. (11801327)

“…A higher CCI was associated with decreased PFS (45.1% vs. 22.2%; <i>p</i> = 0.012), but it did not influence the risk of recurrences or death (<i>p</i> = 0.360; <i>p</i> = 0.111). …”

Table_1_Correlation between ratio of fasting blood glucose to high density lipoprotein cholesterol in serum and non-alcoholic fatty liver disease in American adults: a population b... by Xianjing Jin (19535434)

“…According to the subgroup analysis, the correlation was stronger in other race, participants at the age <50 years old and those with non-diabetes. In this study, a non-linear relationship and saturation effect between GHR and the prevalence of NAFLD was also revealed, characterized by an inverted L-shaped curve, with an inflection point of 7.443. …”

Salispheres contain stem cells. by Isabelle M. A. Lombaert (82763)

“…At day 3 and later time-points, nearly all cells at the periphery of the salispheres showed high Sca-1 expression which decreased in time (D10). (B) Approximately 52.0+/−3.1% (Mean+/−STDEV) of cells in D3 cultured spheres expressed Sca-1, as quantified by flow cytometry. …”

Effect of dilution factor and replicate number on the reproducibility of αSyn^D seed concentration estimates in PD (A-D) and DLB (E-H) brain homogenates by ED RT-QuIC ass... by Ankit Srivastava (742990)

“…Horizontal dotted lines in A, C, E, G denote 50% positive wells. Data points in B, F, D, H indicate log₁₀ SD50/mg brain tissue, with horizontal and vertical bars indicating the mean and 95% CI respectively.…”

DataSheet1_Efficacy and safety of traditional Chinese medicine for intracranial hemorrhage by promoting blood circulation and removing blood stasis: A systematic review and meta-an... by Wenjian Lin (9774764)

“…The pooled outcomes indicated that BACM combined with western medicine treatment (WMT) was superior to WMT alone for patients with ICH, demonstrated by the improvements in efficacy (RR = 1.22 (95% CI, [1.13 to 1.32], p < 0.001), neurological functions (MD_NIHSS = −2.75, 95% CI [−3.74 to −1.76], p < 0.001), and activities of daily living (MD_{Barthel index} = 5.95, 95% CI [3.92 to 7.98], p < 0.001), as well as decreased cerebral hematoma, cerebral edema (MD cerebral hematoma = −2.94, 95% CI [−3.50 to −2.37, p < 0.001 and MD_{cerebral edema} = −2.66, 95% CI [−2.95 to −2.37], p < 0.001), side effects and mortality (RR = 0.84 (95% CI [0.60 to 1.19], p = 0.330 and RR = 0.51 (95% CI, [0.16 to 1.65], p = 0.260). …”

Data Sheet 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.pdf by Lei Xiang (528500)

“…</p>Results<p>ORes significantly reduces breast cancer cell viability and proliferation in a concentration-dependent manner, with IC₅₀ values of 104.8 μM, 150.2 μM, and 143.6 μM in MDA-MB-231, BT-549, and 4T1 cells, respectively. …”

Image_2_Sedentary behavior, brain-derived neurotrophic factor and brain structure in midlife: A longitudinal brain MRI sub-study of the coronary artery risk development in young ad... by Xuan Zhang (56049)

“…</p>Results<p>Cross-sectionally, baseline participants with the highest sedentary time had a lower total brain (−12.2 cc; 95%CI: −20.7, −3.7), gray matter (−7.8 cc; 95%CI: −14.3, −1.3), and hippocampal volume (−0.2 cc; 95%CI: −0.3, 0.0) compared with populations with the lowest sedentary time. …”

Data Sheet 1_Association of SGLT2 inhibitors with post-ablation atrial fibrillation recurrence in individuals with heart failure or type 2 diabetes mellitus: a systematic review an... by Jiaqi Li (220961)

“…Subgroup analyses showed consistent reductions in recurrence risk in individuals with AF and T2DM (RR: 0.74, 95% CI: 0.68–0.80, p < 0.001) as well as those with AF and HF (RR: 0.61, 95% CI: 0.50–0.74, p < 0.001). Furthermore, SGLT2i corresponded to reduced all-cause mortality (RR: 0.66, 95% CI: 0.48–0.91, p = 0.010), fewer rehospitalization (RR: 0.79, 95% CI: 0.72–0.88, p < 0.001), and a lower incidence of thromboembolic events (RR: 0.56, 95% CI: 0.36–0.86, p = 0.009).…”