Selective cytotoxicity of AQHAR in human cancer cells. by Kejuan Li (2580184)

“…Human osteosarcoma (U2OS) cells showed dose-dependent decrease in viability; normal fibroblasts (TIG-3) were not affected by the equivalent doses (B) Phase contrast images of human cancer and normal cells showing toxicity of AQHAR (50 μg/ml) to cancer cells only. …”

The disorganized nature of SP8⁺ interneurons in GL and the expression level of SP8⁺ interneurons. by Zhenzu Li (3108309)

“…Lgl1 conditional mice exhibited severe disorganization in OB interneurons and an almost complete loss of interneurons in the GL at P21. There was a noticeable decrease of SP8⁺ interneurons in the GL of Lgl1 mutants (f^,) compared to WT controls (f). …”

Artemisinin Inhibits Yeast Respiratory Growth by Depolarizing the Mitochondrial Membrane by Wei Li (7081)

“…The peak shift toward the left represents a decrease of fluorescence signal indicating the loss of membrane potential. …”

The probability of tumor nodule eradication increases with the increase of CTL number. by Claire Christophe (714134)

“…Other lines: same evolution when the mean killing time is decreased by 10%, 50% and 90%. …”

Mitochondrial fatty acid uptake and complex IV inhibition by palmitoylcarnitine in early type-2 diabetic hearts. by Phing-How Lou (198977)

“…N = 5–6 hearts per group. Data are or mean ± SD (panels A) or mean ± SEM (panel B).</p>…”

Overexpression of miR-105 inhibits tumour cell growth but does not induce apoptosis. by D. Rice Honeywell (442714)

“…<p>(A–B) Tumour cells were transfected with either 50 nM miR-105 (closed squares) or control (open circles) mimics and subsequently seeded into 96-well plates in replicates of 8. …”

PTEN was the downstream target of miR-21 in inducing angiogenesis. by Ling-Zhi Liu (20849)

Leptin-induced relaxation of phenylephrine-preconstricted mesenteric artery rings in different experimental groups. by Anna Jamroz-Wiśniewska (514346)

“…EC₅₀– leptin concentration (ng/ml) which induced a half-maximal relaxation of PE-preconstricted segments. …”

Effects of AG-490 and WHI-P154 on nuclear translocation of STAT1α in IFN-γ-stimulated J774 macrophages by Outi Sareila (66176)

Characterization of phenotypically unique accessions. by Maria Stefania Przybylska (22756354)

“…</i></i> common accessions classification. Mean Decrease Accuracy (top) and Mean Decrease Gini (bottom) of the random forest models are presented. …”

Srp drives an overgrowth of the wing disc. by Kyra Campbell (582914)

“…Expression of <i>sna</i> results in a small, but significant decrease in wing disc size (B, D), whereas <i>srp</i> drives a large increase in the size of the GFP expressing compartment (C, D). …”

Overexpression of ST6GAL1 gene enhances the chemoresistance of K562 cells both in vitro and in vivo. by Hongye Ma (424073)

“…IC₅₀ represents the drug concentration producing 50% decrease of cell growth. …”

Immunoblotting of SHP in cisplatin-induced renal injury. by Eun Hui Bae (413566)

“…<p>SHP protein expression was reduced in cisplatin-induced renal injury mice, and it was attenuated by FXR ligand treatment (A). In HK-2 cells, SHP protein exhibited significantly decreased expression after cisplatin (50 µM, 16 h) treatment, and FXR ligand (20 µM, 1 h) pretreatment prevented this cisplatin-mediated decrease in SHP expression (B). …”

Cx43 distribution in CA3 after epileptiform activity. by Erika R. Kinjo (642091)

“…(B, C) Quantification of mean pixel intensity (n = 4 animals per group) showed significant increase in SP and decrease in SR in the acute period (E) compared to controls (D). …”

Telomerase mutant zebrafish have shorter telomeres than WT siblings. by Catarina M. Henriques (102294)

“…D) TRF mean sizes were calculated as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003214#pgen.1003214-Kimura1" target="_blank">[50]</a>. …”

ST266 attenuates RGC loss in mice with mild-moderate EAE optic neuritis. by Keirnan Willett (9946075)

“…(a) The average normalized RGC count across the entire retina shows a decrease in RGC numbers in vehicle-treated EAE mouse eyes (n = 22 eyes) compared to eyes from non-EAE control mice (n = 44 eyes) (*p<0.05). …”

Depletion of TGF-β alters morbidity in HK/486-infected mice. by Christina M. Carlson (240307)

“…<p>Six hours before infection, BALB/c mice were treated with a TGF-β neutralizing antibody (1D11) or an isotype control antibody (IgG) at a dose of 0.5 mg/mouse and subsequently inoculated with PBS (control) or 10⁵ TCID₅₀ units of HK/486 virus (n = 15). …”

Hippocampal cell proliferation and neurogenesis in the dentate gyus. by Suk-Yu Yau (205104)

“…However, BDNF level was decreased by CORT in a dose-dependent manner. Running up-regulated BDNF level in 30 mg/kg and 40 mg/kg CORT-treated rats, but not in 50 mg/kg CORT-treated rats. …”

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Summary of collateral dependent blood flow measurements made using manual and automated inflation protocols for before and after transient repetitive myocardia ischemia (RI). by Silas J. Leavesley (555725)