Image_3_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.tif by H. Mark Kenney (10320665)

“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b⁺ plasma cells localized in MARCO⁺ peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”

MiR-29b-2-5p, through repression of UNC5C expression, increases filopodia formation and <i>Shigella</i> capture by host cells. by Ushasree Sunkavalli (3916721)

“…Internalization and replication of <i>Shigella</i> within host cells lead to decreased levels of miR-29b-2-5p, which contributes to a balanced intracellular replication, avoiding premature cell death and favoring the efficient dissemination of <i>Shigella</i> to neighboring cells.…”

Sustained activation of β-catenin in the somatic cells leads to the induction of p53-mediated senescence in <i>Amhr2-Cre;Ctnnb1^Δ(ex3)/+</i> ovaries. by Pradeep S. Tanwar (143924)

“…Analyses also showed increased expression of pAKT and pS6K, and decreased expression of p21 and p27kip1 in <i>Amhr2-Cre;Ctnnb1^Δ(ex3)/+;Pten^Δ/Δ</i> ovaries. β-actin was used as a loading control. …”

Optical Activity and Dehydration-Driven Switching of Magnetic Properties in Enantiopure Cyanido-Bridged Co^II₃W^V₂ Trigonal Bipyramids by Szymon Chorazy (1396666)

“…The reversible removal of weakly bonded H₂O above 50 °C induces the structural phase transition <b>1</b> ⇄ <b>1deh</b> and strongly affects the magnetic characteristics. …”

Optical Activity and Dehydration-Driven Switching of Magnetic Properties in Enantiopure Cyanido-Bridged Co^II₃W^V₂ Trigonal Bipyramids by Szymon Chorazy (1396666)

“…The reversible removal of weakly bonded H₂O above 50 °C induces the structural phase transition <b>1</b> ⇄ <b>1deh</b> and strongly affects the magnetic characteristics. …”

Data_Sheet_1_Early Changes in B and Plasma Cell Subsets and Traditional Serological Markers as Predictors of SRI-4 Response to Therapy in Systemic Lupus Erythematosus.docx by Ioannis Parodis (2851211)

“…</p>Results<p>In the analysis of the entire cohort, SRI-4 responders showed more prominent decreases from baseline through week 52 in CD19⁺CD20⁺CD27^– naïve B cells (median change: −61.2% versus −50.0%; P = 0.004), CD19⁺CD20^–CD27^bright plasmablasts (−44.9% versus −33.3%; P = 0.011), and CD19⁺CD20^–CD138⁺ long-lived plasma cells (−48.2% versus −37.1%; P = 0.024), and a more prominent rapid (+92.0% versus +66.7%; P = 0.002) and early (+60.0% versus +49.5%; P = 0.033) expansion of CD19⁺CD20⁺CD27⁺ memory B cells than non-responders. …”

Bacterial strains used in this study. by Nobuo Fuke (22190368)

“…We cultured <i><i>Escherichia coli</i></i> OP50 (the standard <i><i>C</i></i>. <i><i>elegans</i></i> food), <i><i>Prevotella</i></i> (<i><i>P</i></i>.) …”

Specificity of 1xSPS₁₅, 2xCSL₁₇ and 2xCSL₁₇mut probes as unlabeled competitors for Su(H). by Yi Kuang (1873354)

“…<p>EMSA data reveals that the addition of the unlabeled 1xSPS₁₅ and 2xCSL₁₇ probes, but not the 2xCSL₁₇mut probe results in decreased Su(H) binding to the labeled 2xCSL₁₇ probe. 3.5nM labeled probe and 40nM Su(H) was used in indicated lanes. …”

MicroRNA and cellular targets profiling reveal miR-217 and miR-576-3p as proviral factors during Oropouche infection by Victor Emmanuel Viana Geddes (5309945)

“…Further validation confirmed that miR-217 and miR-576-3p were 5.5 fold up-regulated at early stages of virus infection (6 hours post-infection). …”

Sox2 expression in <i>Sox2-</i>siRNA and control <i>MF1</i>x<i>CD1</i> embryos. by Maria Keramari (237523)

“…(<b>B</b>) Control and <i>Sox2</i>-duplex-2-siRNA embryos stained for Sox2 (Abcam) on days 4 and 5: single optical sections from confocal Z-series, DAPI-stained nuclei (blue) and Sox2 (green); bar: 50 µm. Decreased Sox2 protein expression was observed in <i>Sox2</i> knock-down morulae on day 4, which persisted on day 5. …”

Creating web-based tools for independent monitoring of functional recovery following total hip arthroplasty by Jeremy Graber (10702935)

“…The possibility of including a longitudinal data collection mechanism within the patient-facing web tool may offer a unique solution to these challenges.…”

Data_Sheet_2_Behavioral and neurophysiological effects of buspirone in healthy and depression-like state juvenile salmon.docx by Sheyda Shapouri (17946893)

“…Furthermore, we attempted to reverse this DLS-like profile through pharmacological manipulation of the serotonin (5-HT) system with buspirone, an anxiolytic medication that acts as a serotonin receptor agonist (i.e., decreases serotonergic signaling). …”

Orofacial myofunctional changes and electromyographic activity of the orbicularis oris muscle in trombonists by Ana Paula Arruda de Moura (4896082)

“…Data collection involved three steps: application of a questionnaire investigating some peculiarities of trombonists (Orofacial Myofunctional Evaluation with Expanded Scores - OMES-E), and electromyographic analysis of the orbicularis oris muscle before and after performing a piece with the trombone. …”

Data_Sheet_1_Behavioral and neurophysiological effects of buspirone in healthy and depression-like state juvenile salmon.xlsx by Sheyda Shapouri (17946893)

“…Furthermore, we attempted to reverse this DLS-like profile through pharmacological manipulation of the serotonin (5-HT) system with buspirone, an anxiolytic medication that acts as a serotonin receptor agonist (i.e., decreases serotonergic signaling). …”

Magnetically-Propelled Fecal Surrogates for Modeling the Impact of Solid-Induced Shear Forces on Primary Colonic Epithelial Cells by Sam Hinman (8963249)

“…The application of these solid-induced shear forces did not deleteriously affect cell monolayer surface coverage, viability, or transepithelial electrical resistance unless the device parameters were raised to a 50× greater contraction frequency and 4× greater fecal velocity than those observed in healthy humans. …”

Numerical integration of the rate equations of the MerB reaction mechanism by Pedro Silva (532059)

“…</p> <p> </p> <p>Syntax is:</p> <p> </p> <p>HgMerB_kinetics [initial concentration of organomercurial (optional)] [number of steps with timestep tightening] [initial_timestep][pH] [type of molecule] [how many seconds of kinetic information you want] [HgMerB (or free MerB) concentration] [concentration of the Hg-removing molecules tested] [barriers in kcal.mol-1 for the 38 reaction steps] [name of output file]</p> <p> </p> <p>Type of molecule is : 1 for MerA, 2 for dithiothreitol, 3 for GSH or other monothiols</p> <p>Notes on the algorithm:</p> <p> </p> <p>A) concentrations are output whenever :</p> <p>A1) concentration of HgMerB decreases by 1%, or</p> <p>A2) concentration of product increases by 1% of initial MerB concentration, or</p> <p>A3) 10^7 integration timesteps have elapsed since the last output (or 3*10^5, if less than 10^7 integration timestpes have elapsed since the beginning of the simulation)</p> <p> </p> <p>B) Integration timestep is scaled to ensure that the concentration of every intermediate does not increase more than 10% of its previous concentration. …”

Effects of Meloxicam on the Welfare of Holstein Calves from 6 Weeks to 6 Months Old Undergoing Amputation Dehorning by Jiancheng Qi (17878619)

“…The outcomes demonstrated that the AD procedure increased the frequencies of ear flicking and resulted in rises in respiration rate, heart rate, rectal temperature, and daily active steps. It also led to decreases in total food intake, forage intake, hay intake, MNT, and increased levels of prostaglandin E2 (PgE2), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), glutathione peroxidase activity (GSH-Px), nitric oxide (NO), and malondialdehyde (MDA). …”

Assembly at different time-scales. by Gui Araujo (22170819)

“…</i> scenarios with assembly events occurring before ecological equilibrium is attained, 5 samples each. The fastest assembly scenario is for 1 event at every 25 time-steps (1/25), then 1 at every 100 time-steps (1/100), and the slowest with 1 at every 1000 (1/1000), all with evolution or invasion happening in the same time-scale as the ecological dynamics. …”

Binding and entry of TP4 peptides in <i>E</i>. <i>coli</i>. by Shih-Han Wang (430693)

“…<p>(A) TP4 and FITC-TP4 peptides exerted similar bactericidal ability against <i>E</i>. …”

Image_6_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg by Chris Marco Mbianda Nana (14492776)

“…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …”