DataSheet_2_Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.csv by Changwei Zheng (13928844)

“…Single nucleotide polymorphisms (SNPs) were chosen as instrumental variables (IVs). We obtained genetic variants associated with lipid exposure at the genome-wide significance (P<5×10⁻⁸) level from a meta-analysis of GWAS from the Global Lipids Genetics Consortium (GLGC) based on 188,577 individuals of mostly European ancestry for MR analyses. …”

Na/K-ATPase signaling mediates miR-29b-3p regulation and cardiac fibrosis formation in mice with chronic kidney disease by Christopher A. Drummond (3845110)

“…Using isolated cardiac fibroblasts from α1+/- mice and their WT littermates, we showed that ouabain, a specific Na/K-ATPase ligand, induces decreased miR-29b-3p expression in fibroblasts isolated from WT mice, but had no effect in cells from α1+/- mice. …”

Table_2_Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.docx by Changwei Zheng (13928844)

“…Single nucleotide polymorphisms (SNPs) were chosen as instrumental variables (IVs). We obtained genetic variants associated with lipid exposure at the genome-wide significance (P<5×10⁻⁸) level from a meta-analysis of GWAS from the Global Lipids Genetics Consortium (GLGC) based on 188,577 individuals of mostly European ancestry for MR analyses. …”

DataSheet_4_Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.csv by Changwei Zheng (13928844)

“…Single nucleotide polymorphisms (SNPs) were chosen as instrumental variables (IVs). We obtained genetic variants associated with lipid exposure at the genome-wide significance (P<5×10⁻⁸) level from a meta-analysis of GWAS from the Global Lipids Genetics Consortium (GLGC) based on 188,577 individuals of mostly European ancestry for MR analyses. …”

DataSheet_6_Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.csv by Changwei Zheng (13928844)

“…Single nucleotide polymorphisms (SNPs) were chosen as instrumental variables (IVs). We obtained genetic variants associated with lipid exposure at the genome-wide significance (P<5×10⁻⁸) level from a meta-analysis of GWAS from the Global Lipids Genetics Consortium (GLGC) based on 188,577 individuals of mostly European ancestry for MR analyses. …”

Table_1_Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.docx by Changwei Zheng (13928844)

“…Single nucleotide polymorphisms (SNPs) were chosen as instrumental variables (IVs). We obtained genetic variants associated with lipid exposure at the genome-wide significance (P<5×10⁻⁸) level from a meta-analysis of GWAS from the Global Lipids Genetics Consortium (GLGC) based on 188,577 individuals of mostly European ancestry for MR analyses. …”

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals by Zari Dastani (144367)

“…We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (<em>P</em> = 4.5×10⁻⁸–1.2×10⁻⁴³). …”

datasheet1_Ozanimod for Treatment of Relapsing-Remitting Multiple Sclerosis in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.docx by Yue Sun (197395)

“…As for the subgroup analysis, compared with 0.5 mg ozanimod, 1 mg ozanimod is related with a significant reduction of the annualized relapse rate during the treatment period (1 mg ozanimod, 0.18; 0.5 mg ozanimod, 0.24; RR, 0.05 [95% CI, 0.01, 0.09])and a decreased number of new or enlarging T2 lesions over the treatment period (1 mg ozanimod,1.58; 0.5 mg ozanimod, 2.05; RR, 0.49 [95% CI, 0.19, 0.79]). …”

datasheet1_Ozanimod for Treatment of Relapsing-Remitting Multiple Sclerosis in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.docx by Yue Sun (197395)

“…As for the subgroup analysis, compared with 0.5 mg ozanimod, 1 mg ozanimod is related with a significant reduction of the annualized relapse rate during the treatment period (1 mg ozanimod, 0.18; 0.5 mg ozanimod, 0.24; RR, 0.05 [95% CI, 0.01, 0.09])and a decreased number of new or enlarging T2 lesions over the treatment period (1 mg ozanimod,1.58; 0.5 mg ozanimod, 2.05; RR, 0.49 [95% CI, 0.19, 0.79]). …”

Aberrant CpG methylation of the <i>TFAP2A</i> gene constitutes a mechanism for loss of <i>TFAP2A</i> expression in human metastatic melanoma by Andrea R Hallberg (686570)

<i>fat-6</i> mRNA levels are induced through NHR-80 in <i>glp-1(e2141ts)</i> animals. by Jérôme Goudeau (228021)

“…Relative to <i>glp-1(e2141ts)</i> mutants, <i>K04A8.5</i> is decreased 6.4-fold in <i>daf-16(mu86);glp-1(e2141ts)</i> mutants (<i>p</i><0.01) and 1.4-fold in <i>glp-1(e2141ts);nhr-80(tm1011)</i> double mutants (Wilcoxon rank-sum test <i>p</i> value is non-significant). …”

Six Year Refractive Change among White Children and Young Adults: Evidence for Significant Increase in Myopia among White UK Children by Sara J. McCullough (846708)

“…The proportion of myopes in the UK has more than doubled over the last 50 years in children aged between 10–16 years and children are becoming myopic at a younger age. …”

Illustrative cases of fractionated radiosurgery for large brain metastases. by Joo Whan Kim (3135003)

“…<p>A 50-year-old woman was diagnosed with brain metastases 4 years after treatment for breast cancer. …”

Data_Sheet_1_Efficacy and Safety of Probiotics for the Treatment of Alzheimer's Disease, Mild Cognitive Impairment, and Parkinson's Disease: A Systematic Review and Meta-Analysis.P... by Shuai Xiang (326486)

“…After screening 1,923 titles and abstracts about PD, we selected 5 eligible studies (n = 342 patients). …”

Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction by Michael C. Bressan (674014)

“…Interestingly, mechanical loading of the embryonic atrial muscle resulted in an induction of <i>Cx40</i>, <i>Nav1.5</i> and the cell cycle marker <i>Cyclin D1,</i> while decreasing atrial pressure via <i>in vivo</i> ligation of the vitelline blood vessels results in decreased atrial conduction velocity. …”

Data from: Responses of subsoil organic carbon to climate warming and cooling is determined by microbial community rather than its molecular composition by Yuzhang Li (20150214)

“…However, warming elevated fungal-to-bacterial biomass ratio (F/B) and gram-positive to gram-negative bacterial biomass ratio (G+/G-) by 15.0% and 8.6%, respectively, whereas cooling reduced them by 4.5% and 9.6%. Warming reduced SOC storage by directly increasing F/B and G+/G- and indirectly decreasing the soil carbon-to-nitrogen ratio, whereas cooling enhanced SOC storage primarily by decreasing F/B. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”