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44501
Table 1_Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime.docx
Published 2025“…Ensembles of MAXENT and General Boosted Models were produced for a 2.1 million ha model domain encompassing BDF’s 672,000 ha range for the period 1981–2010, and were projected to 2040–2069 and 2070–2099 using three climate models (warmer-wetter, warmer, and hotter-drier) under a high emission scenario (IPCC 5th Assessment, RCP 8.5). Wildfire projections were analyzed only for mid-century based on warmer-wetter and hotter-drier climate scenarios. …”
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44502
Image_2_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.jpeg
Published 2024“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”
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44503
Is the risk of progressive multifocal leukoencephalopathy the real reason for natalizumab discontinuation in patients with multiple sclerosis?
Published 2017“…Despite introduction of the currently employed PML risk stratification algorithm, the incidence of natalizumab-associated PML cases is not decreasing.</p><p>Objectives</p><p>We addressed the following questions: How do natalizumab-treated multiple sclerosis patients and their treating physicians assess and deal with PML risk? …”
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44504
Image_1_Blockade of growth hormone receptor signaling by using pegvisomant: A functional therapeutic strategy in hepatocellular carcinoma.tif
Published 2022“…Mechanistically, pegvisomant decreased the phosphorylation of GHR downstream survival proteins including JAK2, STAT3, STAT5, IRS-1, AKT, ERK, and IGF-IR. …”
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44505
Image_1_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.jpeg
Published 2024“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”
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44506
Table_1_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.xlsx
Published 2024“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”
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44507
Image_4_Blockade of growth hormone receptor signaling by using pegvisomant: A functional therapeutic strategy in hepatocellular carcinoma.tif
Published 2022“…Mechanistically, pegvisomant decreased the phosphorylation of GHR downstream survival proteins including JAK2, STAT3, STAT5, IRS-1, AKT, ERK, and IGF-IR. …”
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44508
Data_Sheet_1_Impact of New-Onset Persistent Left Bundle Branch Block on Reverse Cardiac Remodeling and Clinical Outcomes After Transcatheter Aortic Valve Replacement.docx
Published 2022“…During a median follow-up of 18.1 months, the new LBBB group experienced a higher incidence of primary outcomes [hazard ratio (HR): 5.03; 95% confidence interval (CI): 2.60–9.73; p < 0.001] and all-cause death (HR: 2.80; 95% CI: 1.38–5.69; p = 0.003). …”
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44509
Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders
Published 2016“…</p><p>Results</p><p>After stringent quality control, we identified decreased levels of long-chain (polyunsaturated) fatty acids of individuals with PD compared to both RLS (PD vs. …”
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44510
Image_2_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG
Published 2020“…Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”
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44511
DataSheet_2_Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma.pdf
Published 2021“…<p>Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. …”
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44512
Image_2_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF
Published 2021“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”
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44513
Table_1_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.xlsx
Published 2024“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”
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44514
Data from flow assays with neutrophils treated with RPMI or bromelain.
Published 2013“…(b) Data from primary human neutrophil flow assays with P-selectin substrates reveal that the number of interacting cells is decreased when neutrophils are treated with 50 µg/mL bromelain in RPMI on regions of “high” and “low” immobilized P-selectin. (** <i>p</i><0.05) Treatment with saturating levels of anti-PSGL-1 clone KPL-1 significantly decreased P-selectin mediated tethering on high P-selectin substrates (** <i>p</i><0.05). …”
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44515
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44516
In vitro analysis of the <i>β-catenin</i>-<i>Gata3</i>-<i>Ret</i> molecular cascade.
Published 2013“…<p>(A, B) Bioinformatic analysis of <i>Gata3</i> and <i>Ret</i> genomic loci 50 kb upstream of the translational start site. …”
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44517
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44518
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44519
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44520
Table_9_Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson’s disease.xlsx
Published 2024“…Only the expressed HLA-DRA*01:01:01 and -DQA1*03:01:01 protective alleles (PD v HC), the -DQA1*03:03:01 risk (HC v Prodrome) or protective allele (PD v Prodrome), the -DRA*01:01:02 and -DRB4*01:03:02 risk alleles (SWEDD v HC), and the NR_SVA_381 present genotype (PD v HC) at a 5% homozygous insertion frequency near HLA-DPA1, were significant (Pc<0.1) after Bonferroni corrections. …”