Table_1_The burden of poisoning in children hospitalised at a tertiary-level hospital in South Africa.pdf by Mahtaab Khan (17257735)

“…Most (71.3%) children were less than 5 years of age and 55% were male. The incidence of poisoning per 100,000 was highest at 108.4 (95% CI: 104.3–112.6) in 2019 and decreased to 77.3 (95% CI: 73.9–80.7) in 2020 and 59.6 (95% CI: 56.3–62.5) in 2021. …”

Supplementary file 1_Quantitative microbial taxonomy across particle size, depth, and oxygen concentration.zip by Paulina Huanca-Valenzuela (21414911)

“…</p>Methods<p>In this study, we quantified microbial diversity using a fractionation method that separated particles into seven fine scale fractions (0.2–1.2, 1.2–5, 5–20, 20–53, 53–180,180–500, >500 μm), and included a spike-in standard for sequencing the 16S rRNA gene. …”

Table 2_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx by Nianfeng Tang (21536069)

“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”

Data_Sheet_1_An Evaluation of Three Ways of Communicating Carrier Status Results to the Parents of Children in a Neonatal Sickle Cell Screening Programme.PDF by Christelle Rémus (8995493)

“…</p><p>Method: In a randomized study, we contacted 300 couples of parents after their child had been identified as a SCD carrier in the French national newborn screening programme: 100 couples received an information letter (the standard procedure in France: arm A), 100 couples received a letter and then a follow-up phone call (arm B), and 100 received a letter and then three follow-up text messages at 5-day intervals (arm C). …”

DataSheet3_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…This study aimed to investigate the regulatory effect of Saikosaponin d (SSD), a monomer extracted from the plant Bupleurum, on peritoneal fibrosis and the contribution of TGFβ1/BMP7/Gremlin1 pathway cross-talk in this process. To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

Image_2_The burden of poisoning in children hospitalised at a tertiary-level hospital in South Africa.JPEG by Mahtaab Khan (17257735)

“…Most (71.3%) children were less than 5 years of age and 55% were male. The incidence of poisoning per 100,000 was highest at 108.4 (95% CI: 104.3–112.6) in 2019 and decreased to 77.3 (95% CI: 73.9–80.7) in 2020 and 59.6 (95% CI: 56.3–62.5) in 2021. …”

Table_2_Subclinical Changes in Left Heart Structure and Function at Preschool Age in Very Low Birth Weight Preterm Infants.docx by Hung-Yang Chang (772494)

“…The objective of this prospective observational study was to assess left heart function at preschool age in preterm children with very low birth weight (VLBW).</p>Methods<p>We recruited children aged 5–6 years from preterm infants and full-term children. …”

Table_1_Shifting Pathways of Stimulant Use Among Individuals With Opioid Use Disorder: A Retrospective Analysis of the Last Thirty Years.docx by Matthew S. Ellis (3390581)

“…Those initiating opioid/stimulant use from 1991 to 1995 had a mean average of 6.8 years between first and second drug exposure, which steadily decreased to 1.5 years between exposures in 2016–2020. …”

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…RNLEs includes 12 common negative life events that have occurred in the past year, and were classified as low RNLEs (0 RNLEs), intermediate RNLEs (1–5 RNLEs), and high RNLEs (6–12 RNLEs). A healthy lifestyle score in adulthood was constructed as the sum of five modifiable lifestyle factors (i.e., smoking status, drinking status, regular physical activity, sleep duration, and living alone), and was classified as unfavorable [0–2 points], intermediate [3 points], and favorable [4–5 points] groups. …”

DataSheet4_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…This study aimed to investigate the regulatory effect of Saikosaponin d (SSD), a monomer extracted from the plant Bupleurum, on peritoneal fibrosis and the contribution of TGFβ1/BMP7/Gremlin1 pathway cross-talk in this process. To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice by Xiao Ling Liu (178263)

“…The present study was undertaken to test the hypothesis that local RNAi of MCP-1 by site-specific delivery of adenovirus-mediated small hairpin RNA (shRNA) may enhance plaque stability and prevent plaque disruption in ApoE−/− mice. We designed an adenovirus-mediated shRNA against mouse MCP-1 (rAd5-MCP-1-shRNA). …”

Data_Sheet_1_Comparison of the effects of rumen-protected and unprotected L-leucine on fermentation parameters, bacterial composition, and amino acids metabolism in in vitro rumen... by Jishan An (17436939)

“…Correlation analysis indicated that there are 5 bacteria at the genus level that may be positively correlated with MCP and propionate (p < 0.05). …”

Vascular Complications after Transfemoral Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis by Zouhair Rahhab (6925127)

“…The pooled major VCs rate was 7.71% and was lower in low-profile vs. high-profile device studies (5.51% vs. 8.46%, <i>p</i> = 0.0015). Major VCs rate decreased significantly with transition to newer generation balloon-expandable valves ((Sapien vs. …”

Data_Sheet_1_Ultrasound-guided anterior iliopsoas muscle space block effectively reduces intraoperative hypotension in elderly adults undergoing hip surgery: A randomised controlle... by Qingyu Teng (14490755)

“…</p>Results<p>Compared to the posterior group, the iliopsoas space block group had a decreased median frequency of IOH [1.09 (0–2. 14) vs. 3 (1.6–4.8), p = 0.001, respectively] along with lower absolute [5 (0–10) min] and relative [minutes below systolic blood pressure of 100 mmHg in % of total anaesthesia time, 6.67 (0–7.65)] duration of IOH compared to the posterior group [35 (10–45) min, p = 0.008; 37.6 (12.99–66.18), p = 0.004, respectively]. …”

Data_Sheet_1_Genetic Predisposition to Low-Density Lipoprotein Cholesterol May Increase Risks of Both Individual and Familial Alzheimer's Disease.DOCX by Jiang-Shan Tan (11584507)

“…</p><p>Results: Genetically predicted LDL-C was positively associated with individual [Odds ratio (OR) = 1.509, 95% confidence interval (CI) = 1.140–1.999; P = 4.0 × 10⁻³], paternal [OR = 1.109, 95% CI = 1.053–1.168; P = 9.5 × 10⁻⁵], maternal [OR = 1.132, 95% CI = 1.070–1.199; P = 2.0 × 10⁻⁵], and family history of AD [OR = 1.124, 95% CI = 1.070–1.181; P = 3.7 × 10⁻⁶] in inverse variance weighted analysis. …”

Prediction of all-cause mortality after liver transplantation using left ventricular systolic and diastolic function assessment by Young-Jin Moon (2696887)

“…In combined LVDF and LVSF analysis, patients with an E/A ratio<0.9 and LVEF≤60% had poorer survival outcomes than patients with an E/A ratio≥0.9 and LVEF>60% (79.5% versus 93.3%, <i>P</i> = 0.001). Patients with an early mitral inflow velocity/annular velocity (E/e’ ratio)>11.5(Q4) and LV stroke volume index (LVSVI)<33mL/m²(Q1) showed worse survival than those with an E/e’ ratio≤11.5 and LVSVI ≥33mL/m²(78.4% versus 92.2%, <i>P</i> = 0.003). …”

Data_Sheet_1_Putative Concussion Biomarkers Identified in Adolescent Male Athletes Using Targeted Plasma Proteomics.PDF by Michael R. Miller (375187)

“…Proximity extension assays were performed for 1,472 plasma proteins; a total of six proteins were considered significantly different between cohorts (P < 0.01; five proteins decreased and one protein increased). …”

DataSheet6_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…This study aimed to investigate the regulatory effect of Saikosaponin d (SSD), a monomer extracted from the plant Bupleurum, on peritoneal fibrosis and the contribution of TGFβ1/BMP7/Gremlin1 pathway cross-talk in this process. To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation by Vittoria Massafra (613864)

“…FGF19 treatment decreased the expression of proteins involved in fatty acid (FA) synthesis, i.e., Fabp5, Scd1, and Acsl3 and increased the expression of Acox1, involved in FA oxidation. …”

Image_1_A 4 bp InDel in the Promoter of Wheat Gene TaAFP-B Affecting Seed Dormancy Confirmed in Transgenic Rice.TIF by Yumei Feng (119912)

“…Background<p>Wheat (Triticum aestivum L.) ABA insensitive five (ABI5) binding protein gene (TaAFP) is a homologue of the ABI5 binding protein (AFP) gene in Arabidopsis thaliana. …”