Cytokines, Chemokines, and their Functions. by Bryan Shin (17833689)

“…This B-cell dysfunction, mediated by the inflammatory cytokines Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), increases the susceptibility of late-stage sepsis patients to nosocomial infections and increases the incidence or severity of recurrent infections, such as SARS-CoV-2, in those with chronic conditions. We propose that modeling B-cell dynamics can aid the investigation of their responses to different levels and patterns of systemic inflammation.…”

Table_3_Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism.do... by Xiao-Chuan Li (3753502)

“…Based on the PPI analysis, the five most significant hub genes were PLK1, KIF20A, RRM2, CDC20, and UBE2C in the M1CM groups and RRM2, CCNB1, CDC20, PLK1, and UBE2C in the M2CM groups. …”

Image1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg by Adam D. Price (19842741)

“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”

Table_1_Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism.do... by Xiao-Chuan Li (3753502)

“…Based on the PPI analysis, the five most significant hub genes were PLK1, KIF20A, RRM2, CDC20, and UBE2C in the M1CM groups and RRM2, CCNB1, CDC20, PLK1, and UBE2C in the M2CM groups. …”

Data_Sheet_1_CD27+CD38hi B Cell Frequency During Remission Predicts Relapsing Disease in Granulomatosis With Polyangiitis Patients.docx by Anouk von Borstel (7421039)

“…<p>Background: Granulomatosis with polyangiitis (GPA) patients are prone to disease relapses. We aimed to determine whether GPA patients at risk for relapse can be identified by differences in B cell subset frequencies.…”

Fair Coins Tend to Land on the Same Side They Started: Evidence from 350,757 Flips by František Bartoš (8998556)

Applications of Human Biostasis in Crewed Space Exploration by Josh Universe (21186797)

“…NASA's STASH program and ESA's hibernation research mark essential steps forward in torpor research, indicating growing institutional support for these technologies.…”

Data_Sheet_1_Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a “Two Hit” Stressor Model.PDF by Christine L. Foxx (9938600)

Data_Sheet_2_Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a “Two Hit” Stressor Model.PDF by Christine L. Foxx (9938600)

The development of anti-PD-1 antibody-induced spinal cord injury in bone marrow transplant C57BL/6 <i>Rag1^-/-</i> mouse model by Huachun Chen (12495577)

BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons by Yuxi Jin (9472045)

Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity by Sayantan Datta (379869)

Table_1_Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a “Two Hit” Stressor Model.XLSX by Christine L. Foxx (9938600)

Subnetworks having different frequency preferences can synchronize their activity if they share gap junctions. by Guillaume Pernelle (4951924)

“…(<b>B</b>) Frequency-transfer characteristics of one single inhibitory neuron to a sub-threshold oscillatory input current (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006025#sec015" target="_blank">Methods</a>) for different values of its membrane time constant <i>τ</i>_<i>v</i>. The sub-threshold resonance frequency decreases as <i>τ</i>_<i>v</i> increases. …”

NI GABAergic cells can disinhibit DG GCs via inhibiting DG SOM interneurons. by Krisztián Zichó (16189450)

“…<p>(A) We infected DG SOM cells with Cre-dependent tracer AAV and NI GABAergic cells with flippase-dependent tracer AAV in double transgenic SOM-Cre/vGAT-Flp mice (<i>n</i> = 4 mice). …”

Graphical summary of research aim and key findings. by Berta Puig (344828)

“…Key hallmarks of prion-associated neuropathology are also altered in the transgenic mice including (iii) decreased PrP^Sc production and deposition, (iv) reduced vacuolization (spongiosis) of the brain parenchyma, and (v) reduced induction of astrocytes and microglia (reactive gliosis). …”

A domed window chamber for multi-modality optical imaging by Photini Rice (20493401)

Natural disease history of the <i>dy^2J</i> mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy by S. Pasteuning-Vuhman (4348486)

“…Wild type and <i>dy</i>^<i>2J</i><i>/dy</i>^<i>2J</i> mice were subjected to five different functional tests from the age of four to 32 weeks. …”

Data release: "Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype" by Megan Hagenauer (7871078)

Global burden of liver cirrhosis 1990–2019 and 20 years forecast: results from the global burden of disease study 2019 by Yikai Wang (1706548)