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31121
siRNA Silencing of Proteasome Maturation Protein (<em>POMP</em>) Activates the Unfolded Protein Response and Constitutes a Model for KLICK Genodermatosis
Published 2012“…<div><p>Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in the 5′untranslated region of the proteasome maturation protein (<em>POMP</em>) gene. …”
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31122
Atmospheric Mercury Outflow from China and Interprovincial Trade
Published 2018“…Chinese interprovincial trade promotes the transfer of atmospheric outflow from the eastern terrestrial boundary (−6.4 Mg year<sup>–1</sup>) to the western terrestrial boundary (+4.5 Mg year<sup>–1</sup>) and a net decrease in the atmospheric outflow for the whole boundary, reducing the chance of risks to foreign countries derived from transboundary Hg pollution from China. …”
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31123
Facile Fabrication of Superhydrophobic and Magnetic Poly(lactic acid) Nonwoven Fabric for Oil–Water Separation
Published 2020“…The fabrication of an eco-friendly superhydrophobic material for oil–water separation is of important theoretical and practical significance. Herein, we proposed a facile method to fabricate a superhydrophobic and magnetic poly(lactic acid) (SMPLA) nonwoven fabric. …”
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31124
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31125
Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice
Published 2019“…Twenty-eight male c57bl/6 mice (6 months old) received ayahuasca or water (1.5 mL/kg, orally) twice a week for 12 months and were tested in the Morris water maze (MWM), open field and elevated plus maze (EPM) tasks before and after treatment. …”
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31126
Data_Sheet_1_Timing Training in Female Soccer Players: Effects on Skilled Movement Performance and Brain Responses.pdf
Published 2018“…Accordingly, this study investigated the effects of timing training on soccer skill performance and the associated changes in functional brain response in elite- and sub-elite female soccer players. Twenty-five players (mean age 19.5 years; active in the highest or second highest divisions in Sweden), were randomly assigned to either an experimental- or a control group. …”
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31127
Image_8_Improved Chloride Ion Sensing Performance of Flexible Ag-NPs/AgCl Electrode Sensor Using Cu-BTC as an Effective Adsorption Layer.jpeg
Published 2019“…<p>We designed the flexible chloride ion selective sensor that directly monitors electrochemical reactions of chloride ions without using a reference electrode. …”
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31128
Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)<sup>†</sup>
Published 2003“…We have investigated conformational transitions in the Klenow fragment polymerase reaction by stopped-flow fluorescence using DNA substrates containing the fluorescent reporter 2-aminopurine (2-AP) on the template strand, either at the templating position opposite the incoming nucleotide (designated the 0 position) or 5‘ to the templating base (the +1 position). …”
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31129
Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)<sup>†</sup>
Published 2003“…We have investigated conformational transitions in the Klenow fragment polymerase reaction by stopped-flow fluorescence using DNA substrates containing the fluorescent reporter 2-aminopurine (2-AP) on the template strand, either at the templating position opposite the incoming nucleotide (designated the 0 position) or 5‘ to the templating base (the +1 position). …”
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31130
Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G‑Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity
Published 2018“…Heptaheteroaryl compounds comprised of oxazole and pyridine units (TOxaPy) are quadruplex DNA (G4)-interactive compounds. Herein, we report on the synthesis of parent compounds bearing either amino side chains (TOxaPy-1–5) or featuring an isomeric oxazole-pyridine central connectivity (iso-TOxapy, iso-TOxapy 1–3) or a bipyridine core (iso-TOxabiPy). …”
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31131
Table_2_Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.docx
Published 2023“…Furthermore, we identified the elevation of two sterols (Lan and Chol), and the reduction of one corticoid (11-DeoxyF) and two progestins (5α-DHP and 11β-OH-Prog) in patients.…”
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31132
Image_1_The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction.PDF
Published 2018“…It is generally believed that Aβ oligomers are the neurotoxic species and their levels in the AD brain correlate with the severity of dementia suggesting that they play a critical role in the pathogenesis of the disease. Here, we show that the incubation of differentiated human neuroblastoma cells (SHSY5Y) with freshly prepared Aβ42 oligomers initially resulted in oxidative stress and subtle nucleolar stress in the absence of DNA damage or cell death. …”
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31133
Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces
Published 2023“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10<sup>5</sup>-fold decrease in the attachment of bacteria from urine. …”
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31134
Data_Sheet_1_Response of Microbial Communities to Changing Climate Conditions During Summer Cyanobacterial Blooms in the Baltic Sea.docx
Published 2018“…These climate-driven changes are expected to alter not solely the phytoplankton community but also the role of microbial communities for nutrient remineralization. Here, we present the response of summer plankton communities (filamentous cyanobacteria, picocyanobacteria, and heterotrophic bacteria) to the interplay of increasing temperature (from 16 to 18°C and 20°C) and reduced salinity (from salinity 6.9 to 5.9) in the Baltic Proper (NW Gotland Sea) using a microcosm approach. …”
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31135
Image_6_Improved Chloride Ion Sensing Performance of Flexible Ag-NPs/AgCl Electrode Sensor Using Cu-BTC as an Effective Adsorption Layer.jpeg
Published 2019“…<p>We designed the flexible chloride ion selective sensor that directly monitors electrochemical reactions of chloride ions without using a reference electrode. …”
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31136
Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment
Published 2022“…NAP, a 6β-N-4-pyridyl-substituted naltrexamine derivative, was previously identified as a potent and selective MOR antagonist mainly acting peripherally but with some CNS effects. Herein, we introduced a highly polar aromatic moiety, for example, a pyrazolyl or imidazolyl ring to decrease CNS MPO scores in order to reduce passive BBB permeability. …”
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31137
Curcumin Improves the Tumoricidal Effect of Mitomycin C by Suppressing ABCG2 Expression in Stem Cell-Like Breast Cancer Cells
Published 2015“…In addition, curcumin sensitized the BCSCs of MCF-7 and MDA-MB-231 to MMC by 5- and 15-fold, respectively. The BCSCs could not grow to the fifth generation in the presence of curcumin and MMC. …”
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31138
Facile Fabrication of Superhydrophobic and Magnetic Poly(lactic acid) Nonwoven Fabric for Oil–Water Separation
Published 2020“…The fabrication of an eco-friendly superhydrophobic material for oil–water separation is of important theoretical and practical significance. Herein, we proposed a facile method to fabricate a superhydrophobic and magnetic poly(lactic acid) (SMPLA) nonwoven fabric. …”
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31139
Facile Fabrication of Superhydrophobic and Magnetic Poly(lactic acid) Nonwoven Fabric for Oil–Water Separation
Published 2020“…The fabrication of an eco-friendly superhydrophobic material for oil–water separation is of important theoretical and practical significance. Herein, we proposed a facile method to fabricate a superhydrophobic and magnetic poly(lactic acid) (SMPLA) nonwoven fabric. …”
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31140