Image_1_Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production.jpeg by Soumya R. Mohapatra (8081411)

DataSheet_2_Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization study.pdf by Likui Lu (6631655)

“…Objective<p>Observational studies suggest an association between hypothyroidism and the risk of hepatocellular carcinoma (HCC), but the causality and direction of these effects are still inconclusive. We aim to test whether hypothyroidism is causally associated with the risk of HCC by using Mendelian randomization (MR) analysis.…”

Zhou BN, Gao P, Hu J, et al. Supplementary materials for: <b>Genetic analysis, phenotype spectrum and functional study of rare osteogenesis imperfecta caused by </b><b><i>CRTAP</i>... by ZHOU Bingna (17706960)

Image_1_A dynamic nomogram to predict invasive fungal super-infection during healthcare-associated bacterial infection in intensive care unit patients: an ambispective cohort study... by Peng Li (69518)

“…Objectives<p>Invasive fungal super-infection (IFSI) is an added diagnostic and therapeutic dilemma. We aimed to develop and assess a nomogram of IFSI in patients with healthcare-associated bacterial infection (HABI).…”

Image_1_Associations Between Sleep Quality and Health Span: A Prospective Cohort Study Based on 328,850 UK Biobank Participants.tif by Muhammed Lamin Sambou (10971984)

“…The hazard ratio (HR) and 95% confidence intervals (CIs) were calculated by multivariate-adjusted Cox proportional hazards model. Moreover, we calculated population attributable risk percentage (PAR%) to reflect the public health significance of healthy sleep quality.…”

Supplementary Material for: Interleukin-24 Suppresses the Growth of Vascular Smooth Muscle Cells by Inhibiting H₂O₂-Induced Reactive Oxygen Species Production by Lee K.-M. (4135666)

Estrogen and Progesterone Regulate p27kip1 Levels via the Ubiquitin-Proteasome System: Pathogenic and Therapeutic Implications for Endometrial Cancer by Kuang-Tzu Huang (132734)

<b><i>N</i></b>^{<strong>6</strong>}<b>-Methyladenosine demethylase FTO controls</b><b>macrophage homeostasis in diabetic vasculopathy</b> by Siguo Feng (19924429)

Table_2_Multiple Myeloma-Derived Extracellular Vesicles Impair Normal Hematopoiesis by Acting on Hematopoietic Stem and Progenitor Cells.xlsx by Ilaria Laurenzana (1528111)

“…Our data showed that: (i) MM cells released a heterogeneous population of EVs; (ii) MM-EVs caused a dose-dependent reduction of HSPCs viability; (iii) MM-EVs caused a redistribution of the HSPC pool characterized by a significant increase in the frequency of stem and early precursors accompanied by a reduction of late precursor cells, such as common myeloid progenitors (CMPs), megakaryocyte erythroid progenitors (MEPs), B and NK progenitors, and a slight increase of granulocyte macrophage progenitors (GMPs); (iv) MM-EVs caused an increase of stem and early precursors in S phase with a decreased number of cells in G₀/G₁ phase in a dose-dependent manner; (v) MM-EVs reduced the HSPC colony formation; and (vi) MM-EVs caused an increased expression level of C-X-C motif chemokine receptor type 4 (CXCR4) and activation of miRNAs. …”

Table_1_Risk factors for cognitive dysfunction amongst patients with cardiovascular diseases.DOCX by Tunde Pal (19662328)

“…The Chi-square test, Cramer’s V test, and correlation analyses were also applied.…”

Supplementary Material for: Functional characterization of gonadotropin-releasing hormone and corazonin signaling systems in Pacific abalone: toward reclassification of invertebrat... by Kim M.A. (16976625)

Image 1_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.jpeg by Weiwei Zheng (140828)

“…</p>Methods<p>In this study, we investigated the changes in intestinal histopathology, intestinal microbiome and host gene expression in resistant and susceptible individuals at 7 days post infection with Vibrio harveyi, and identified the host gene-microbe correlations. …”

DataSheet1_Eocene-Oligocene southwest Pacific Ocean paleoceanography new insights from foraminifera chemistry (DSDP site 277, Campbell Plateau).XLSX by F. Hodel (14131221)

Sustained activation of autophagy suppresses adipocyte maturation via a lipolysis-dependent mechanism by Xing Zhang (11943)

Data_Sheet_2_Exploring the Potential of CRISPR-Cas9 Under Challenging Conditions: Facing High-Copy Plasmids and Counteracting Beta-Lactam Resistance in Clinical Strains of Enteroba... by Thaysa Leite Tagliaferri (6371453)

“…One innovative approach is the CRISPR-Cas9 system which has recently been used for plasmid curing in defined strains of Escherichia coli. Here we exploited this system further under challenging conditions: by targeting the bla_TEM–₁ AMR gene located on a high-copy plasmid (i.e., 100–300 copies/cell) and by directly tackling bla_TEM–₁-positive clinical isolates. …”

DataSheet_1_Development and characterization of a CRISPR/Cas9-mediated RAG1 knockout chicken model lacking mature B and T cells.docx by Kyung Youn Lee (12794388)

“…<p>Although birds have been used historically as a model animal for immunological research, resulting in remarkable achievements, immune cell development in birds themselves has yet to be fully elucidated. In this study, we firstly generated an immunodeficient chicken model using a CRISPR/Cas9-mediated recombination activating gene 1 (RAG1) knockout, to investigate avian-specific immune cell development. …”

Table 9_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx by Weiwei Zheng (140828)

“…</p>Methods<p>In this study, we investigated the changes in intestinal histopathology, intestinal microbiome and host gene expression in resistant and susceptible individuals at 7 days post infection with Vibrio harveyi, and identified the host gene-microbe correlations. …”

Data_Sheet_1_Influence of 37 Years of Nitrogen and Phosphorus Fertilization on Composition of Rhizosphere Arbuscular Mycorrhizal Fungi Communities in Black Soil of Northeast China.... by Qingfeng Wang (1356576)

“…In this context, a long-term fertilizer experiment (37 years) was set up in the black soil of northeast China. We examined interaction impacts of elevated fertilizer and host selection processes on arbuscular mycorrhizal fungi (AMF) communities in wheat rhizosphere soil using the Illumina MiSeq platform. …”

Contrasting roles of cytochrome P450s in amitraz and chlorfenapyr resistance in the crop pest <i>Tetranychus urticae</i> by Thomas Van Leeuwen (13004790)

Supplementary Material for: A Comparison of Serial Position Effects in Patients with Mild Cognitive Impairment due to Parkinson’s Disease or to Alzheimer’s Disease by Meyer A. (3224046)