Ductal branching is dependent upon phenotype heterogeneity within MCF10A in 3-D culture. by Russell Gould (3603524)

“…For compaction and tubular assays, cells were embedded into collagen gels for 72 hrs, and the extent of tubulogenesis was measured at 7 days. (A-D) Within MCF10A, TGF−<i>β</i>2 (10ng/ml) enhanced invasion and contractile properties while, VEGFA (50ng/ml) promoted increased migration. …”

Ubr3 is required for Hh signaling and proper optic vesicle morphogenesis. by Tongchao Li (115391)

Image_5_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Aβ-induced BACE1 mRNA and protein expressions in activated N2a Swe cells and their reductions by taxifolin and cilostazol. by So Youn Park (141327)

“…Significant decreases in BACE1 protein expression by taxifolin (50 or 100 μM), cilostazol (30 μM), and by 30 μM quercetin (a flavonoid) after 24 hr of treatment. …”

Image_5_CRISPR/Cas9-Mediated Knockout of Galactinol Synthase-Encoding Genes Reduces Raffinose Family Oligosaccharide Levels in Soybean Seeds.JPEG by Huy Le (9856877)

Declining ELT-2 expression during aging limits lifespan. by Frederick G. Mann (263292)

RNA-seq transcriptional profiling of <i>Leishmania amazonensis</i> reveals an arginase-dependent gene expression regulation by Juliana Ide Aoki (3109917)

“…The absence of arginase activity in promastigotes increased the levels of pyrroline 5-carboxylate reductase, but decreased the levels of arginosuccinate synthase, pyrroline 5-carboxylate dehydrogenase, acetylornithine deacetylase and spermidine synthase transcripts levels. …”

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication by Jun Li (6494)

“…The percentage of the sarcomere shortening (bl% peak h), departure velocity (dep v) of sarcomere shortening and time to 50% of the peak speed of myocyte contraction (Tp50) was assessed by a video-based edge-detection system. …”

S1 Dataset - by Gui-Hong Zhang (9284601)

“…Additionally, we showed that upregulation of 5-HTR1A dampened the Tβ4 to activate ERK signalling. …”

Table_5_New evidence for the effect of type 2 diabetes and glycemic traits on testosterone levels: a two-sample Mendelian randomization study.xlsx by Chengyang Jiang (1540369)

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked by their decreasing “order of importance”, for various years;... by Marcel Ausloos (748325)

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked according to their decreasing “order of importance”, for vario... by Marcel Ausloos (748325)

Estimated demographic history in four simple demographic scenarios with seed banking where <i>μ</i> = 2.5 × 10⁻⁹. by Thibaut Paul Patrick Sellinger (8677419)

“…We have <i>β</i> = 1 (red), 0.5 (blue), 0.2 (green) and 0.1 (purple). …”

Differentially expressed genes in <i>erg251Δ/Δ</i> in YPAD compared to wild-type in YPAD. by Xin Zhou (54275)

CD8 and CD4 Epitope Predictions in RV144: No Strong Evidence of a T-Cell Driven Sieve Effect in HIV-1 Breakthrough Sequences from Trial Participants by Kalpana Dommaraju (650755)

“…Comparisons between the vaccine and placebo arm did not reveal robust evidence for a T cell driven sieve effect, although some differences were noted in Env-V2 (0.022≤p-value≤0.231). The paucity of CD8 T cell responses identified following RV144 vaccination, with no evidence for V2 specificity, considered together both with the association of decreased infection risk in RV 144 participants with V-specific antibody responses and a V2 sieve effect, lead us to hypothesize that this sieve effect was not T cell specific. …”

S2 Fig - by Pierre Ganault (17972799)

Data_Sheet_2_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_1_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_3_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_4_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”