Image_1_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif by Chien-Ming Lin (740034)

“…</p>Objective<p>A 45-year-old male presenting with moderate hypercalcemia, hypocalciuria, and inappropriately high parathyroid hormone (PTH) had a good response to cinacalcet (total serum calcium (Ca²⁺) from 12.5 to 10.1 mg/dl). …”

Image_2_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif by Chien-Ming Lin (740034)

“…</p>Objective<p>A 45-year-old male presenting with moderate hypercalcemia, hypocalciuria, and inappropriately high parathyroid hormone (PTH) had a good response to cinacalcet (total serum calcium (Ca²⁺) from 12.5 to 10.1 mg/dl). …”

Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa by Lin Li (28817)

“…<div><p>We identified a homozygous missense alteration (c.75C>A, p.D25E) in <i>CLCC1</i>, encoding a presumptive intracellular chloride channel highly expressed in the retina, associated with autosomal recessive retinitis pigmentosa (arRP) in eight consanguineous families of Pakistani descent. …”

Effect of exogenous Spd on kale seeds germination under chilling stress. by Dongdong Cao (350033)

Drug-Eluting versus Bare-Metal Stent for Treatment of Saphenous Vein Grafts: A Meta-Analysis by Pascal Meier (207362)

“…The mortality was not significantly different between DES and BMS in the RCT's (OR 2.22 [0.17 – 29.50]; p = 0.546) while the observation studies showed a decreased mortality in the DES group (0.69 [0.55–0.85]; p<0.001).…”

Average yield from historical records and for the GLOBIOM baseline for crops (a) and for non-dairy ruminant meat (b) by H Valin (557174)

“…Our results confirm that yield increase could mitigate some agriculture-related emissions growth over the next decades. Closing yield gaps by 50% for crops and 25% for livestock by 2050 would decrease agriculture and land use change emissions by 8% overall, and by 12% per calorie produced. …”

Geographic distribution by group. by Megayn E. Lewandowski (18599144)

“…</p><p>Objectives</p><p>We tested the following hypotheses: the pandemic and consequent policies (1) increased use of alcohol and illicit substances in active users; (2) increased use of alcohol/substances among people in early recovery; (3) reduced participation in recovery activities among those in early recovery, and that (4) use amount and use events correlated with impulsivity in both groups and that (5) substance use and abstinence correlated with resilience.…”

Charge-State-Dependent Collision-Induced Dissociation Behaviors of RNA Oligonucleotides via High-Resolution Mass Spectrometry by Rui-Xiang Sun (1797622)

“…Specifically, when the precursors had a charge from 1^– to 5^–, the fractional intensity of sequencing ions decreased, while that of precursors that underwent either neutral or charged losses of a nucleobase increased. …”

Charge-State-Dependent Collision-Induced Dissociation Behaviors of RNA Oligonucleotides via High-Resolution Mass Spectrometry by Rui-Xiang Sun (1797622)

“…Specifically, when the precursors had a charge from 1^– to 5^–, the fractional intensity of sequencing ions decreased, while that of precursors that underwent either neutral or charged losses of a nucleobase increased. …”

Demographics. by Megayn E. Lewandowski (18599144)

“…</p><p>Objectives</p><p>We tested the following hypotheses: the pandemic and consequent policies (1) increased use of alcohol and illicit substances in active users; (2) increased use of alcohol/substances among people in early recovery; (3) reduced participation in recovery activities among those in early recovery, and that (4) use amount and use events correlated with impulsivity in both groups and that (5) substance use and abstinence correlated with resilience.…”

Charge-State-Dependent Collision-Induced Dissociation Behaviors of RNA Oligonucleotides via High-Resolution Mass Spectrometry by Rui-Xiang Sun (1797622)

“…Specifically, when the precursors had a charge from 1^– to 5^–, the fractional intensity of sequencing ions decreased, while that of precursors that underwent either neutral or charged losses of a nucleobase increased. …”

Self-reported life events. by Megayn E. Lewandowski (18599144)

“…</p><p>Objectives</p><p>We tested the following hypotheses: the pandemic and consequent policies (1) increased use of alcohol and illicit substances in active users; (2) increased use of alcohol/substances among people in early recovery; (3) reduced participation in recovery activities among those in early recovery, and that (4) use amount and use events correlated with impulsivity in both groups and that (5) substance use and abstinence correlated with resilience.…”

Table_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Table_2_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Intracellular free magnesium measurements. by Selma Metaane (12329248)

Data_Sheet_1_Efavirenz restored NMDA receptor dysfunction and inhibited epileptic seizures in GluN2A/Grin2a mutant mice.PDF by Teng Zhao (1486717)

“…Mice with GluN2A/GRIN2A-V685G mutation exhibited shorter latency to seizure, increased frequency of seizure-like events, decreased peak current and current area of NMDAR excitatory postsynaptic current, and decreased event frequency of micro-inhibitory postsynaptic current, compared to WT mice. …”

Transmission of tuberculosis in rural Henan, China: a prospective population-based genomic spatial epidemiological study by Zhuo Quan (17658835)

“…The clustering risk decreased rapidly with increasing distances between patient residences, but 77.6% of clustered patient pairs lived ≥5.0 km apart. …”

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review by Sarah Elshahat (8587107)

“…Mean EuroQol-5D index scores ranged from 0.80 to 0.86 for CKD stages 1–3, and decreased to 0.73–0.79 for CKD stages 4–5. …”

PRISMA flow diagram. by Nicole E. Smolinski (18840931)

“…</p><p>Results</p><p>24 studies were included. Antibiotics decreased the risk of acute mastoiditis [incidence 0.02%, RR 0.48, 95% CI 0.40–0.59; NNT 5,368]. …”

Characteristics of included studies. by Nicole E. Smolinski (18840931)

“…</p><p>Results</p><p>24 studies were included. Antibiotics decreased the risk of acute mastoiditis [incidence 0.02%, RR 0.48, 95% CI 0.40–0.59; NNT 5,368]. …”