Botulinum toxin A-induced muscle paralysis stimulates Hdac4 and differential miRNA expression by Leah E. Worton (457030)

Physio-Biochemical Composition and Untargeted Metabolomics of Cumin (<i>Cuminum cyminum</i> L.) Make It Promising Functional Food and Help in Mitigating Salinity Stress by Sonika Pandey (834285)

“…Relative water content remained unchanged up to 50 mM NaCl stress, and thereafter decreased significantly. …”

Loss of <i>FGR41</i> modestly delays hyphal development <i>in vitro</i>. by Andrew S. Wagner (11331477)

γHV68-IκBαM–Infected Mice Have Decreased Splenic Latency at Later Timepoints after Intranasal Infection that Is Not Altered by Inhibiting Lytic Replication by Laurie T Krug (68237)

Histological analysis of the aorta. by Rodrigo Barbosa de Souza (7866368)

“…<p>(A) (i, ii, iii) Weigert Staining of the tunica media showed elastic fiber fragmentation in MFS animals (black arrowheads); (iv, v, vi) TEM analysis showing micro-fragmentation of the elastic fiber in MFS animals (dashed arrow); Both techniques showed continuous elastic fibers in the WT samples (i, iv, arrow); (vii, viii, ix) Picrossirus red staining showed little prevalence of type I collagen surrounding the elastic fibers in WT samples (white arrows). …”

LOS sialylation does not compete with polyP for the protection from cathelicidin LL-37. by Benedetta Manca (15810991)

Linear mixed model results: Effect of bar height and approach stride number on kinetics at take-off to a jump in agility dogs. by Leena Inkilä (20614460)

Leukocyte adherence in wild type (WT) and eNOS deficient (eNOS^-/-) mice during control conditions and after the application of PEEP (positive end-expiratory pressure). by Aigul Moldobaeva (339313)

“…</b> The number of leukocytes adhered to tracheal post-capillary venules was summed over the course of 1 hr from measurements at 0, 20, 40, and 60 min (Σ 0–60). eNOS^-/- mice show decreased adherence during control experimental conditions (n = 5−6 mice/group); *p = 0.015). …”

<i>Nf1</i> OPG mice show decreased spontaneous alternations in a Y-maze but no deficits in spatial working memory or long-term depression (LTD) in hippocampal slices. by David F. Wozniak (78177)

Membrane-localized AR facilitates productive endocytosis and nuclear trafficking of KSHV. by Xing Wang (154377)

“…Cells were performed as mentioned above, except lacking of Triton X-100 treatment in non-permeabilized group. Scale bars represent 50 μm. (c) Knockdown of AR and EphA2 expression reduces KSHV endocytosis, as indicated by decreasing gB staining in cells. …”

Model parameters. by Nan Zhang (46264)

“…If the mask-wearing rate increases from 0% to 50%, the infection risk of norovirus would be decreased by 48.0% (95% CI, 43.5–52.3%). …”

Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo by Zhiqiang Li (102723)

“…The overexpression of NIK plays a critical role in liver inflammatory diseases. …”

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…We added their proxy variants in LD (r² ≥ 0.8; based on 1000 genomes project data [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref050" target="_blank">50</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref051" target="_blank">51</a>]). …”

Video_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.mov by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Presentation_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.pdf by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Table_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.XLS by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Preliminary dose-response experiments. by Noelia Torremadé (3687523)

Effect of vinculin and Rab5 expression on cellular uptake. by Makoto Hagiwara (513898)

“…Uptake of pHrodo red-labeled <i>S. aureus</i>, transferrin Alexa 555, albumin Alexa 555, Lucifer yellow, and FM 4-64 increased in HA-Rab5 (WT)- and HA-Rab5 (Q79L)-expressing cells, whereas uptake of each of the indicators was decreased in HA-Rab5 (S34N)-expressing cells. …”