Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP^Sc Glycoform and Prion Infectivity by Elizaveta Katorcha (628696)

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

The effects of β₁-adrenoceptor stimulation on I_Kur and I_Kto,f. by Vladimir E. Bondarenko (411443)

“…Simulated currents are obtained by 4.5-s depolarizing pulses to between −80 and +50 mV (in 10-mV increment) from a holding potential of −90 mV. …”

Royal jelly arranges apoptotic and oxidative stress pathways and reduces damage to liver tissues of rats by down-regulation of Bcl-2, GSK3 and NF-κB and up-regulation of caspase an... by Abdullah Aslan (9997699)

“…</p> <p><b>Results</b></p> <p>RJ caused a significant decrease in MDA level, Bcl-2, GSK3 and NF-κB protein expression levels, whereas induced a significant increase in GSH level, CAT activities and Bax, BDNF, caspase-6, caspase-3, Nrf-2 protein expression levels.…”

Increased Myeloid Progenitors in Twist-2–Deficient Mice by Andrew B Sharabi (269342)

“…<div><p>(A) Flow cytometry of splenocytes cultured in complete medium and stimulated with TNFα (5 μg/ml) for 24 h. Cells were stained with CD11b, Gr-1, and Annexin-V antibodies and PI to determine relative apoptotic and necrotic populations from one of the representative repeated experiments.…”

Helper sites and the C-clamp are not required for basal repression of Wg targets in <i>Drosophila</i>. by Chandan Bhambhani (586316)

“…Mutation of two Helper sites leads to a significant decrease in the lacZ expression in the second constriction (arrow) with weak ectopic expression (arrowheads)(G–I). …”

p53 Stabilization Induces Cell Growth Inhibition and Affects <em>IGF2</em> Pathway in Response to Radiotherapy in Adrenocortical Cancer Cells by Camilla Sampaoli (134086)

“…However, it is generally fatal, with an overall survival of 5 years from detection. Radiotherapy usefulness for ACC treatment has been widely debated and seems to be dependent on molecular alterations, which in turn lead to increased radio-resistance. …”

Single channel recording of ELIC. by Iwan Zimmermann (117942)

“…<p>(A) Patch clamp recordings of ELIC expressed in <i>Xenopus oocytes</i> in the outside-out configuration at −60 mV. The agonist (5 mM cysteamine) was applied by a fast solution exchange (black bar above). …”

Opposite effects of Nodal and Oep on <i>rasl11b</i> expression. by Guillaume Pézeron (38267)

“…(B–M, Dorsal view of gastrulae save C, I, sagittal sections and G, lateral view) (B, C) In wild-type (WT) embryos <i>rasl11b</i> is expressed at the animal pole (arrows) and at the dorsal margin (black arrowheads). …”

Functional polymorphism of the <i>CSNK2A1P</i> genes on the degradation of PML tumor suppressor protein. by Ming-Szu Hung (246305)

“…(C) 293T cells were co-transfected with PML-V5 and Myc-tagged CSNK2A1 or CSNK2A1P constructs. …”

Data_Sheet_1_Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus.PD... by Jon Egaña-Huguet (11089344)

“…These functional changes were associated with an increase in the maximum binding efficacy of guanosine-5′-O-(3-[³⁵S]thiotriphosphate) ([³⁵S]GTPγS) stimulated by the CB₁ receptor agonist CP 55,940, and a significant decrease in receptor basal activation in the TRPV1-/- hippocampus. …”

ERK affects CRE-luciferase reporter activity. by William M. Vanderheyden (231718)

“…<i>C</i>, Sleep profile of flies expressing a wild type version of <i>UAS-RSK</i>^<i>wt</i> displayed a decrease in sleep. <i>D</i>, Total sleep is significantly decreased in RSK over expressing flies. p = 0.0261; student’s t-test, n= 31-32/group. …”

Figure 5 from Membrane-bound Heat Shock Protein mHsp70 Is Required for Migration and Invasion of Brain Tumors by Maxim Shevtsov (15023874)

“…<b>A–C,</b> mHsp70 expression in nontreated C6, T98G, U251 cell lines and cells incubated with 1 μmol/L PES or 50 nmol/L JG98 inhibitors. …”

Polyol-responsiveness of anti-EBNA1 mAbs. by Sarah J. Duellman (374308)

“…After the anti-EBNA1 mAbs are bound to the EBNA1-coated well, either a control buffer (TE: 50 mM Tris-HCl, pH 7.9+0.1 mM EDTA) or a salt-polyol buffer (AS/PG: TE buffer+1 M ammonium sulfate+40% propylene glycol or NaCl/PG: TE buffer+1 M NaCl+40% propylene glycol) was added to the wells. …”

FRACTAL AGGREGATES EVOLUTION DURING FLOCCULATION by R. B. Moruzzi (6542864)

“…The Gf values of 20, 30, 40, 50 and 60 s-1 and Tf values of 2 to 180 minutes were studied, with a ΔTf of 1 minute for 2 ≤ Tf ≤ 10 minutes and a ΔTf of 5 minutes for 10 ≤ Tf ≤ 180 minutes. …”

Model resin composites incorporating ZnO-NP: activity against S. mutans and physicochemical properties characterization by Natasha Lamego Brandão (5188793)

“…Materials and Methods Different concentrations of ZnO-NP (wt.%): E1=0, E2=0.5, E3=1, E4=2, E5=5 and E6=10 were incorporated into a model resin composite consisting of Bis-GMA-TEGDMA and barium borosilicate particles. …”

DataSheet1_Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracting the “Pola” expeditions.pdf by Jonathan R. Heath (19465312)

“…The Red Sea Forel-Ule colour increased by 0.83 (± 0.08) with an average decrease in Secchi depth of 5.07 m (± 0.44). The Forel-Ule colour in the Eastern Mediterranean increased by 0.50 (± 0.07) and the historic Secchi depth readings were an average of 8.85 m (± 0.47) deeper than present day. …”

DataSheet1_Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracing the “Pola” expeditions.pdf by Jonathan R. Heath (19465312)

“…The Red Sea Forel-Ule colour increased by 0.83 (± 0.08) with an average decrease in Secchi depth of 5.07 m (± 0.44). The Forel-Ule colour in the Eastern Mediterranean increased by 0.50 (± 0.07) and the historic Secchi depth readings were an average of 8.85 m (± 0.47) deeper than present day. …”

Image 1_Obesity reprograms the normal pancreas and pancreatic cancer microbiome in mice and humans.pdf by Raquel Santana da Cruz (21795701)

“…Recent studies showed that tumors, including PDAC, harbor a microbiome that is able to regulate cancer outcomes such as tumor progression, response to therapy and overall survival. …”

DataSheet2_Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracting the “Pola” expeditions.csv by Jonathan R. Heath (19465312)

“…The Red Sea Forel-Ule colour increased by 0.83 (± 0.08) with an average decrease in Secchi depth of 5.07 m (± 0.44). The Forel-Ule colour in the Eastern Mediterranean increased by 0.50 (± 0.07) and the historic Secchi depth readings were an average of 8.85 m (± 0.47) deeper than present day. …”