Sera selected from national STI surveillance system shows <i>Chlamydia trachomatis</i> PgP3 antibody correlates with time since infection and number of previous infections by Paula B. Blomquist (6061163)

“…With the double-antigen ELISA, the increase was from 61.1% (95%CI: 53.2–60.7) to 97.0% (95%CI: 88.5–99.3). Seropositivity decreased with time since CT diagnosis on only the indirect assay, to 49.3% (95%CI: 40.9–57.7) two or more years after a first diagnosis and 51.9% (95%CI: 33.2–70.0) after a repeat diagnosis.…”

Effect of MMP-2 activity inhibition on PARP-1 degradation. by Hiroyuki Kato (562772)

Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423 by Tomoko Kashiyama (162572)

“…Here, we describe the anti-tumor effect of DS-7423 on a panel of nine OCCA cell lines. IC₅₀ values for DS-7423 were <75 nM in all the lines, regardless of the mutational status of <i>PIK3CA</i>. …”

High Out-of-pocket Health Care Cost Burden Among Medicare Beneficiaries With Diabetes, 1999–2017 by Joohyun Park (1366980)

“…</p> <p><b>Results </b></p> <p>Total OOP costs were $3,609 to $5,283, with significant increases until 2005 followed by a leveling off. …”

Table_1_Oleanolic Acid Mitigates 6-Hydroxydopamine Neurotoxicity by Attenuating Intracellular ROS in PC12 Cells and Striatal Microglial Activation in Rat Brains.DOCX by Zama N. P. Msibi (7292738)

DataSheet1_Whole-Genome Sequencing of Sinocyclocheilus maitianheensis Reveals Phylogenetic Evolution and Immunological Variances in Various Sinocyclocheilus Fishes.docx by Ruihan Li (6611660)

“…We obtained a genome assembly of 1.7 Gb with a scaffold N50 of 1.4 Mb and a contig N50 of 24.7 kb. …”

DataSheet8_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

DataSheet7_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

The SNAP Cycle and Diabetes Management During a One-Time Change in Disbursement Schedule by Sabrina K. Young (12529594)

Supplementary Material for: Blood Pressure Variability in Fabry Disease Patients by Dincer M.T. (9984839)

A bio-inspired robotic climbing robot to understand kinematic and morphological determinants for an optimal climbing gait by Christofer Clemente (6437156)

Quantitative electroencephalography in children with attention deficit hyperactivity disorder and healthy children: Behavioral and age correlates by Nezla S. Duric (17623426)

An example of subnetworks which influence reliability. by Aaditya V. Rangan (305264)

Reproductive ecology and territorial behavior of Boana goiana (Anura: Hylidae), a gladiator frog from the Brazilian Cerrado by Tailise M. Dias (9224835)

Table_1_Clinical application value of metagenomic next-generation sequencing in the diagnosis of spinal infections and its impact on clinical outcomes.xlsx by Guang Zhang (766712)

“…The positive rate of mNGS for diagnosing spinal infections was significantly higher than that of microbiological culture (X²=83.92, P<0.001), procalcitonin (X²=44.34, P<0.001), white blood cells (X²=89.21, P < 0.001), and IGRAs (Interferon-gamma Release Tests) (X² = 41.50, P < 0.001). After surgery, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) showed a decreasing trend in the patients with spinal infections in both the TM and EM groups. …”

Tra2β protein levels are drastically reduced in the brains of neuronal specific <i>Sfrs10</i> knockout mice and correlate with defects in splicing of the <i>Nasp-T</i> cassette and... by Sushma Grellscheid (191887)

“…<p>(A) Whole brain sections derived from 16.5 dpc <i>Sfrs10</i>^fl/wt; Nestin-Cre^tg (left panel) and <i>Sfrs10</i>^fl/fl; Nestin-Cre^tg (right panel) stained with antibodies against Tra2β. …”

Neurons are uncorrelated during PABA and exhibit Poisson-like irregularity. by Nigel Stepp (683934)

“…<p>A) Neuronal firing is weakly correlated during ongoing activity in awake monkeys that display neuronal avalanches in the local field potential (LFP) Distributions of pair-wise correlation coefficients of firing in the pre-motor cortex of two awake monkeys, S1 (1.2 Hz mean rate) and S2 (5.2 Hz mean rate). …”

The role of HBP1 and Wnt signaling in acquired seizure susceptibility. by Roaya S. Alqurashi (11243136)

“…Survival curves were made for the first 5 days after seizure induction. (n = 5 mice for each group). …”

LNCaP cell lines expressing Abi1 isoforms exhibit different spreading and morphological phenotypes. by Patrycja M. Dubielecka (249192)

“…Iso-2 cell line exhibited a significantly decreased mean cell area as compared to Iso-3 or mock control cell lines. …”

Image_3_OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.tif by Longwei Xu (655781)

“…Activation of the OX40 pathway aggravates allergic diseases, such as asthma, but it is not clear whether OX40 is expressed in eosinophils to regulate inflammation in EGIDs. In this study, we assessed the expression and effect of OX40 on eosinophils in WT and Ox40^-/- eosinophilic gastroenteritis (EGE) mice.…”