microRNA-142-3p inhibits apoptosis and inflammation induced by bleomycin through down-regulation of Cox-2 in MLE-12 cells by F. Guo (1715818)

“…Cox-2, PI3K, AKT and mTOR expressions were detected by western blotting after bleomycin was administered together with NS-398 (an inhibitor of Cox-2). As a result, cell viability was significantly decreased, as well as apoptosis and the expression of IL-1 and TNF-α were remarkably increased after 50 and 100 μg/mL of bleomycin administration. miR-142-3p overexpression alleviated bleomycin-induced apoptosis and overproduction of these two pro-inflammatory cytokines, while miR-142-3p suppression exhibited completely opposite results. …”

Regulation of HBV replication by agarose gel analysis in cells treated with miRNA. by Sun O. Park (319202)

Effects of depletion and inactivation of PAR-2 on cell apoptosis. by Song Han (470055)

Modulation of Cell Surface Protein Free Thiols: A Potential Novel Mechanism of Action of the Sesquiterpene Lactone Parthenolide by Jolanta Skalska (256579)

“…Using flow cytometry, and western blotting to label free thiols with Alexa Fluor 633 C₅ maleimide dye and N-(biotinoyl)-N-(iodoacetyl) ethylendiamine (BIAM), respectively, we show that parthenolide decreases the level of free exofacial thiols on Granta mantle lymphoma cells. …”

Image_1_Relevance of PSGL-1 Expression in B Cell Development and Activation.jpeg by Rafael González-Tajuelo (2562418)

“…PSGL-1^−/− mice showed reduced frequencies of peripheral B cells and reduced B cell lineage-committed precursors in the bone marrow. In the spleen of WT mice, the highest percentages of PSGL-1⁺ populations were shown by Breg (90%), B1a (34.7%), and B1b (19.1%), while only 2.5–8% of B2 cells expressed PSGL-1; however, within B2 cells, the class-switched subsets showed the highest percentages of PSGL-1⁺ cells. …”

Image_2_The Role of graRS in Regulating Virulence and Antimicrobial Resistance in Methicillin-Resistant Staphylococcus aureus.JPEG by Le Chen (1446445)

“…Moreover, on the Galleria mellonella infection model, the survival rate at day 5 post infection in the USA500ΔgraRS group (55%) was obviously higher than that in the USA500 group (20%), indicating graRS knockout leads to a decreased virulence in vivo. …”

Microarray and K-means cluster analyses of genes regulated by TRH and by thyroid hormone in TRH-deficient pituitary. by Yasuyo Nakajima (316579)

“…B) In addition to the TSHβ genes, cluster 5 contained the Egr-1, NR4A1, Glt2, and Tmsb10 genes. …”

Image_2_Relevance of PSGL-1 Expression in B Cell Development and Activation.jpeg by Rafael González-Tajuelo (2562418)

“…PSGL-1^−/− mice showed reduced frequencies of peripheral B cells and reduced B cell lineage-committed precursors in the bone marrow. In the spleen of WT mice, the highest percentages of PSGL-1⁺ populations were shown by Breg (90%), B1a (34.7%), and B1b (19.1%), while only 2.5–8% of B2 cells expressed PSGL-1; however, within B2 cells, the class-switched subsets showed the highest percentages of PSGL-1⁺ cells. …”

Image_1_The Role of graRS in Regulating Virulence and Antimicrobial Resistance in Methicillin-Resistant Staphylococcus aureus.JPEG by Le Chen (1446445)

“…Moreover, on the Galleria mellonella infection model, the survival rate at day 5 post infection in the USA500ΔgraRS group (55%) was obviously higher than that in the USA500 group (20%), indicating graRS knockout leads to a decreased virulence in vivo. …”

Supplementary materials for PhD thesis “The Origin of Basaltic Lava Flow Textures” by Marie-Noëlle Guilbaud (2843387)

“…The increasing size and decreasing number density of plagioclase microlites with increasing depth in these flows, as in the Laki lavas, indicate that solidification rates decreased sharply inwards. …”

Effect of BMI1 siRNA transfection on cell viability in Abrams OSA cells. by Mehdi Hayat Shahi (561596)

Genomic relationship among and between the large and small genome groups. by Lisa L. Ellis (603714)

Larval antennae mediate responses to yeast and DEET. by Chao Liu (43092)

Reproducibility of quantitative coronary computed tomography angiography in asymptomatic individuals and patients with acute chest pain by Martina C. de Knegt (6086756)

“…Reproducibility of plaque composition decreased with decreasing plaque density (intraobserver and interobserver CCC for dense calcium (>0.99; 0.98), fibrotic (0.96; 0.93), fibro-fatty (0.95; 0.91), and necrotic core tissue (0.89; 0.84). …”

Supplementary Material for: Evaluation of Antidepressant-Like Activity of Novel Water-Soluble Curcumin Formulations and St. John's Wort in Behavioral Paradigms of Despair by Kulkarni S.K. (4131091)

“…A subeffective dose (50 mg/kg) of these formulations enhanced the antidepressant-like effect of classical antidepressants with varied mechanisms of action. …”

Signaling pathways of the interspecies molecular mechanisms based on the HVCP in Fig 6 at the second infection stage of EBV infection. by Cheng-Wei Li (2831708)

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer by Anju Singh (21688)

“…Sequencing of <em>KEAP1</em> in 12 cell lines and 54 non-small-cell lung cancer (NSCLC) samples revealed somatic mutations in <em>KEAP1</em> in a total of six cell lines and ten tumors at a frequency of 50% and 19%, respectively. …”

Fig 7 - by Wiebke Tebrün (8843852)

Coarse- and fine-grain landscape categories used in this study. by Amanda E. Nelson (597554)

Identification of a HacA-independent gene regulatory network mediated by IreA. by Xizhi Feng (193742)