Data_Sheet_2_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…The models were also applied to estimate all-cause excess deaths “not directly attributable to COVD-19”, i.e., without a previous COVID-19 diagnosis. During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Mitochondrial superoxide governs cell number. by Tejas M. Gupte (743674)

“…(the depletion of mitofusin alone) to 5.4 x 10⁸ ± 0.7 x 10⁸. Values are mean ± SD from a three experiments with 50 cells per genotype.…”

Comparison of the Simulated Activities of PI3K, Membrane-Bound PTEN, and the Resulting Behavior of PIP₃ (Composite Screenshot) by Martin Meier-Schellersheim (63389)

“…<p>Stimulation of a cell in a 2:1 cAMP gradient (mean concentration 500 nmol) leads to a rapid 3-fold increase in the membrane proximal activity of PI3K (green) and to a loss of membrane-bound PTEN (blue; tracked as GFP-PTEN in real cells). …”

Effects of adenosine receptor-specific antagonists on responses to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…At both ages, heart rates were not affected by SCH-58261 treatment (A and B). In contrast, at both ages DPCPX elevated heart rates above vehicle levels in normoxic conditions and inhibited hypoxia-mediated heart rate decrease below baseline (A and B). …”

Transmembrane signaling in cell-derived plasma membrane vesicles. by Luigino Grasso (208932)

“…(D) The FRET signal increases with the concentration of agonist APEC added to the bulk solution (concentrations indicated above the bars in nM). (E) A dose-dependent increase of the FRET yields <i>EC₅₀</i> = 100±11 nM; shown are averages and standard deviations of the mean of nine titration experiments each performed on different, individual vesicles.…”

Effect of AZT and LAC treatments on brain oxidative stress in newborn and adult mice. by Anna Rita Zuena (89723)

Effect of selected compounds on the induction of the luciferase signal at the CMV-luc construct in KG-1 cells. by Dante Rotili (462382)

Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107 by Yingwu Mei (102313)

“…The 1,4-benzothiazepine derivative JTV519, and the more specific derivative S107 <b>(</b>2,3,4,5,-tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine), are thought to improve skeletal muscle function by stabilizing the RyR1-FKBP12 complex. Here, we report a high degree of nonspecific and specific low affinity [³H]S107 binding to SR vesicles. …”

Effect of HETE on REC barrier function. by Amira Othman (380131)

Enhancing the number of human otic sensory cells by Notch inhibition. by Hanae Lahlou (5394905)

“…(D) The decrease of Notch pathway components after DBZ treatment was accompanied with a significant upregulation of two otic sensory markers (<i>ATOH1</i>, <i>MYO7A</i>) transcripts. …”

Blockade of β₃AR completely restores attenuated HPV in IH rats. by Hisashi Nagai (650547)

“…The tungsten wire in the lower right corner of each image is a reference wire with a diameter of 50 μm. (B, C) Relationship between vessel size and the extent of the pulmonary vasoconstriction (% decrease in vessel diameter) induced in response to acute hypoxia in the N and IH rats treated with or without SR59230A. …”

Functional evaluation of CTB-ESAT6 fusion protein in fresh and lyophilized lettuce leaves. by Priya Saikumar Lakshmi (287441)

“…<p>A, Ganglioside GM1 ELISA binding assay of CTB-ESAT6 derived from total leaf protein (TLP) of transplastomic plants. 1, 2∶15 µg TLP from CTB-ESAT6 transplastomic plants; WT, 15 µg TLP from untransformed lettuce plant; CTB, purified CTB standard; BSA, 50 ng bovine serum albumin. …”

Image_2_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Moreover, the ratio of Chl a and Per showed a relative decrease of Per with increasing PAR intensity. …”

Image_1_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Moreover, the ratio of Chl a and Per showed a relative decrease of Per with increasing PAR intensity. …”

Effects on global translation and lambda light chain synthesis. by Yijiang Shi (548692)

feature parameters by CHIN-CHENG CHU (20718575)

Peak calcium induced by somatic BAP decays with distance in both experiments and model simulation. by David C. Sterratt (158383)

“…<p><b>A</b>, Two-photon compressed z-stack morphology of CA1 pyramidal neuron. …”

Arterial contractility 18 hours after CASP. by Stefan Felix Ehrentraut (136865)

“…In WT mice sham surgery led to a 17% decrease of vascular contractility, compared to 45% after CASP-treatment. …”

Average player As’ transfers across rounds and resulting earnings. by Christoph Eisenegger (430948)

“…Player As increase their transfers over the 20 rounds when paired with a prosocial player B and decrease their transfers while interacting with a selfish player B. …”

The presynaptic changes in the inhibitory synaptic currents in the neocortex evaluated by PPR. by Ulyana Lalo (506296)

“…(A–C) Graphs show the representative IPSCs (average of 25 traces) evoked with a 50 ms interval in control and during application of 10 µM TFLLR. …”