HepG2 cells clear LPS in LDLR-dependent manner. by Elena Topchiy (3171567)

“…Scrambled siRNA was reversely transfected into HepG2 cells, than treated similarly as described above with PCSK9 as a complementary approach to decreasing LDLR. Data presented as mean fluorescence intensity, mean±SEM (n = 3). …”

Metabolic and neuronal origins of the intrinsic flavoprotein signal response. by Cedric R. Uytingco (3371243)

“…<p><b>(A)</b> Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI. …”

Chronic administration of FT₂Fc. by Anna Henzi (9635793)

“…<p>(a) Design of the prophylactic treatment experiment in ZH3 and WT mice. …”

Temporal Trend in Young-Onset Type 2 Diabetes - the Macrovascular and Mortality Risk: Study of UK Primary Care Electronic Medical Records by Digsu N. Koye (8881108)

“…The incidence rates of ASCVD and ACM declined in people aged ≥50 years, but did not decrease in people <50 years. …”

Data_Sheet_1_Hybrid Gibbsite Nanoplatelet/Cellulose Nanocrystal Multilayered Coatings for Oxygen Barrier Improvement.PDF by Maud Chemin (5931452)

“…The measurement of the oxygen transmission rate (OTR) at 23°C and 50% RH showed that the oxygen barrier properties of the bare substrates could be significantly improved (e.g., 75% decrease of the OTR) after the deposition of such thin (<100 nm) multilayered hybrid films. …”

Sulfur supply effects on production and mineral nutrition of Tanzania guinea grass under barium levels in nutrient solution by Arnon Afonso de Souza Cardoso (9980536)

“…The combinations with high S and Ba levels resulted in a decrease of 1.7-fold in leaf area compared to combinations with high S without Ba. …”

TNFα stabilizes myocardin mRNA through MEK/MAPK and NF-κB pathways. by Pavneet Singh (657177)

“…<p>(<b>A</b>) VSMCs were serum-starved for 24 h and transcription was blocked using α-amanitin (50 µM). …”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

Network firing activity during spontaneous and stimulated conditions. by Gustavo Deco (50143)

“…<p>The network cohesion and inhibition levels are and , respectively. (<b>A</b>) Firing activity for network neurons (10 neurons in each population, as indicated on the right): raster plot (black) together with the mean rate (red curves) for each population, obtained as the convolution of the spike trains with a unit Gaussian function with 50 ms width. …”

Supplementary Material for: The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway by Zhou Y. (3218202)

“…<b><i>Results:</i></b> Inhibition of autophagy by the administration of chloroquine prevented the development of HPH in the rat model, as evidenced by significantly reduced mPAP and RVP, as well as decreased autophagy. U50,488H mimicked the effects of chloroquine, and the effects of U50,488H were blocked by nor-BNI, a selective κ-opioid receptor antagonist. …”

Collateral effects are pervasive and vary across parallel evolution experiments in <i>E</i>. <i>faecalis</i>. by Jeff Maltas (1598305)

“…Although the color scale ranges from a 4× decrease to a 4× increase in IC₅₀, it should be noted that both resistance to the selecting drug (diagonal blocks) and collateral effects can be significantly higher. …”

Assessment of transcriptome associated with endothelium activation and blood-brain barrier integrity. by Nana O. Wilson (399957)

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

PCB19 blunts thapsigargin-induced increases in sustained [Ca²⁺]_i levels. by Se-Young Choi (175210)

“…<p><b>A</b>, Fura-2-loaded PC12 cells were treated with 1 μM thapsigargin; 5 minutes later (at the sustained phase), cells were challenged with 50 μM of either PCB4, PCB19, or PCB100. …”

Bariatric surgery and the coronary artery calcium score. by Daniel da Costa Lins (6879683)

“…Results: the FRS decreased 50% between the pre and postoperative evaluations. …”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”