DataSheet_1_Dual targeting of glutamine and serine metabolism in acute myeloid leukemia.pdf by Kanwal M. Hameed (18386853)

“…Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant. …”

Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis by Manresa M.C.

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Effect of HLA-C spatial patterning on target cells on signal integration in NK cells. by Rajdeep Kaur Grewal (12563150)

“…<p>We co-localized KIR-2DL2-HLA-C complexes in a ring pattern at t = 0 in our simulations as shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010114#pcbi.1010114.g006" target="_blank">Fig 6A</a>. …”

Data_Sheet_1_Planktic Foraminiferal Assemblages in Surface Sediments From the Subpolar North Atlantic Ocean.docx by Nibedita Sahoo (12061931)

“…From this, we suggest a shift in planktic assemblages in the SPNA. …”

Data_Sheet_1_Long-Term Data Reveal the Associations of the Egg Quality With Abiotic Factors and Female Traits in the Baltic Herring Under Variable Environmental Conditions.PDF by Marjut Rajasilta (11595226)

“…The total lipid resources of spawning females decreased by 40–50% during the study, and the ovarian lipid concentration followed this trend resulting in a decrease of the lipid content of eggs. …”

Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells by Bolun Wang (1465285)

Treatment of gp130^757FF mice with WP1066 reduces tumour size. by Louise M. Judd (185660)

“…Antral tumours in 8 week untreated mice (A) and 10 week DMSO-treated vehicle controls (B) were no different in mean area, however WP1066 treatment resulted in ∼50% smaller tumours (C). …”

M002 infection and cell survival. by Michael L. Megison (469463)

“…After 72 hr of treatment, cell viability was measured with alamarBlue™ assays. Data reported as mean ± standard error of the mean. There was a significant decrease in viability in all cell lines following M002 treatment. …”

Splenectomy Associated Changes in IgM Memory B Cells in an Adult Spleen Registry Cohort by Paul U. Cameron (210950)

“…Changes of asplenia in routine blood films including presence of Howell-Jolly bodies (HJB), occurred early (median 25 days) and splenectomy associated thrombocytosis and lymphocytosis peaked by 50 days. There was a more gradual decrease in IgM memory B cells reaching a stable level within 6 months after splenectomy. …”

Image_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.TIF by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

Video_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.MP4 by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

Table_1_Investigation of the impact of machine operating parameters on beam delivery time and its correlation with treatment plan characteristics for synchrotron-based proton penci... by Xiaoying Liang (552537)

“…Reducing the total spill change time and scanning magnet preparation and verification time from those of the 2025 system further reduced BDT in the hypothetical future system. 8 MEE layers per spill is optimal for a system with 50% recapture efficiency; 16 MEE layers per spill is optimal for a system with 80% recapture efficiency; and more than 16 MEE layers per spill is beneficial only for a system close to 100% recapture efficiency.…”

Image1_Second generation androgen receptor antagonist, TQB3720 abrogates prostate cancer growth via AR/GPX4 axis activated ferroptosis.tif by Zhongqing Zhang (9317126)

Data_Sheet_1_The Association Between Shift Work and Immunological Biomarkers in Nurses.PDF by Bjørn Bjorvatn (35254)

“…Furthermore, we aimed to determine whether these biomarkers differ after a night of sleep vs. at the end of a night or a day shift (study 2).…”

Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency by Arne Björn Potthast (4529689)

“…</p><p>Results</p><p>We observed a significant decrease in cellular levels of all three sirtuins at the activity, protein and transcriptional level (by 15% to 50%) in COX-deficient cells. …”

Carob (Ceratonia siliqua L.) Prevents Short-Term Memory Deficit Induced by Chronic Stress in Rats by Alzoubi K.H.

“…This impairment could be attributed to a decrease in brain-derived neurotrophic factor (BDNF) levels during chronic stress. …”
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Swimming training prevents coronary endothelial dysfunction in ovariectomized spontaneously hypertensive rats by E.R.G. Claudio (6509999)

“…These effects were prevented by SW, and were associated with a decrease in oxidative stress. Superoxide dismutase 2 (SOD-2) and catalase expression increased only in the OSW group. …”

Oil-Resistant Underoil Superhydrophilic Metallic Foams for Lampblack Prefiltration by Junxu Chen (5324705)

“…Hence, the LSH coating with great durability on metallic foam for lampblack prefiltration resulted in a 9.3% decrease in the oil absorption weight ratio after a 17-day cooking test. …”

Putative Effect of Aquifer Recharge on the Abundance and Taxonomic Composition of Endemic Microbial Communities by Renee J. Smith (204039)

“…Following wastewater addition, a 25-fold decrease in abundance was observed, coinciding with a 12-fold increase in viral abundance. …”

Designing Driver Assistance Systems with Crossmodal Signals: Multisensory Integration Rules for Saccadic Reaction Times Apply by Rike Steenken (560176)

“…This two-stage model postulates that crossmodal interaction occurs only if the peripheral processes from the different sensory modalities terminate within a fixed temporal interval, and that the amount of crossmodal interaction manifests itself in an increase or decrease of second stage processing time. …”