Image_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.tif by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Image_2_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.tif by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Table_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.docx by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Density curves and moments of TiTv distance as a function of average MAF , given by Eq 142, and Ti/Tv ratio <i>η</i>, given by Eq 127. by Bryan A. Dawkins (10113319)

“…<p>We fix <i>m</i> = <i>p</i> = 100 for all simulated TiTv distances. (<b>A</b>) For fixed , TiTv distance density is plotted as a function of increasing <i>η</i>. …”

Data_Sheet_1_Salt Stress Tolerance of Dark Septate Endophytes Is Independent of Melanin Accumulation.docx by Dalia A. Gaber (9753104)

“…Melanin content increased in the hyphae of all DSEs at 100 mM salt, but decreased at 500 mM. This was not reflected in the RNA accumulation of the gene encoding scytalone dehydratase which is involved in melanin biosynthesis. …”

Late morphogenesis vibrissa follicle abnormalities in <i>Trps1^Δgt/Δgt</i> embryos. by Katherine A. Fantauzzo (122846)

“…<p>(A) <i>Trps1^+/+</i> and <i>Trps1^Δgt/Δgt</i> embryos at E16.5. …”

The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA by Nuri A. Temiz (171116)

“…In addition, the CpG dinucleotide is a known hot spot for pathologic mutations genome-wide. …”

Scribble is required for normal myelin initiation in vitro. by Andrew A. Jarjour (343100)

“…D; Decreased contact and wrapping by MBP-expressing oligodendrocytes was observed in Scribble siRNA-transfected oligodendrocytes (shown in B) relative to those that were mock-transfected or transfected with non-targeting siRNAs (shown in A). …”

The effect of PGJ2 or Mdivi-1 treatment on cortical neurons under normal and OGD conditions. by Edina A. Wappler (303781)

“…Mdivi-1 was not protective in 3 h OGD, and at higher doses (75, 100 µmol/L) it decreased cell viability in control neurons. …”

Projections of the impact of Combination II intervention on HIV incidence. by Ramzi A. Alsallaq (276295)

“…Incidence reductions of more than 65% are delineated and the star marks IRR value with behaviour change assumptions as in (A) and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054575#pone-0054575-t002" target="_blank">Table 2</a> (<b>C</b>) Projections of percentage reduction in incidence of the Combination II intervention with respect to current standard incidence projection of 2.1 (1.9–2.3) per 100 pyar at year 15 with various assumptions of failure to achieve the uptake levels of the interventions in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054575#pone-0054575-t002" target="_blank">Table 2:</a> (IIa) decreasing community testing uptake to 60% in community testing rounds, (IIb) doubling the drop out rate on treatment to 28% per year, (IIc) halving the uptake of circumcision to 35% of uncircumcised men, and (IId) assuming no risk behaviour change following HIV diagnosis generated by the testing.…”

Global Pyrogeography: the Current and Future Distribution of Wildfire by Meg A. Krawchuk (265459)

“…How future climate change may alter global wildfire activity, however, is still largely unknown. As a first step to quantifying potential change in global wildfire, we present a multivariate quantification of environmental drivers for the observed, current distribution of vegetation fires using statistical models of the relationship between fire activity and resources to burn, climate conditions, human influence, and lightning flash rates at a coarse spatiotemporal resolution (100 km, over one decade). …”

Loss of dFOXO suppresses the cell-number reduction in mutants by Martin A Jünger (2646)

“…Each graph displays the variation of a single parameter between the five genotypes shown in (a-e): body weight, cell number in the eye, cell size in the eye, wing area, cell number in the wing, and cell size in the wing. …”

Critical irradiation doses as a function of Wip1 (<i>s</i>₁) and PTEN (<i>s</i>₂) mRNA synthesis rates. by Beata Hat (202211)

“…<p>(A) Active PI3K level is decreased 2-fold from the nominal value. …”

Dexamethasone, CRTC2 and PGC-1α expression. by Jill A. Rahnert (2872766)

“…<p>(A) A representative western blot confirms infection of L6 myotubes with virus encoding CRTC2 increases nuclear CRTC2 protein. …”

Table4_Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone.XLSX by Hagar A. Morgaan (15350347)

“…The latter effects disappeared in LPS/PE preparations, suggesting a postconditioning action for LPS against renal manifestation of PE. …”

VisAccel complete data_redacted2.xlsx by Miguel A. Yakouma (21439852)

“…When the velocity profile of the visual stimulus matched the velocity profile of inertial motion, the inertial stimulus was biased 10.0 ± 1.8° (mean ± SE) with a 45° visual offset, 8.9 ± 1.7° with a 60° offset, and 9.3° ± 2.5 ± with a 75° offset. …”

Trends and Disparities in Rates of Hypoglycemia Among Hospitalized Patients with Type II Diabetes by Paul A Heidenreich (13188712)

“…Black (adjusted odds ratio -aOR, 1.42 95% CI 1.36-1.49) or Hispanic patients (aOR 1.26 95% CI 1.17-1.35) had a greater risk of hypoglycemia compared with non-Hispanic White patients and women had borderline less hypoglycemia than men (aOR 0.95, 95% CI 0.89-1.00)</p><p dir="ltr">Conclusion: Inpatient hypoglycemia in the VA Health System has been declining though there are race, age and gender differences that remain unexplained. …”

Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle by Jonathan A. Hardman (714625)

“…Over 24 hours we found a significant reduction in protein levels of BMAL1 and PER1, with their transcript levels also decreasing significantly. …”

Table8_Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone.XLSX by Hagar A. Morgaan (15350347)

“…The latter effects disappeared in LPS/PE preparations, suggesting a postconditioning action for LPS against renal manifestation of PE. …”

Table6_Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone.XLSX by Hagar A. Morgaan (15350347)

“…The latter effects disappeared in LPS/PE preparations, suggesting a postconditioning action for LPS against renal manifestation of PE. …”