Table1_Safety, Pharmacokinetics/Pharmacodynamics, and Absolute Bioavailability of Dexmedetomidine Hydrochloride Nasal Spray in Healthy Subjects: A Randomized, Parallel, Escalating... by Yun Kuang (1731493)

“…In Part 2 and Part 3, the optimized nasal spray method was adopted to promote the Fabs of Dex nasal spray to 74.1%–89.0%. A severe adverse event was found in Part 2. In Part 3 (100 μg), the Ramsay score increased the most and lasted the longest, whereas the BIS score decreased most significantly.…”

Evolution of fEPSPs evoked in the CA1 area by paired-pulse stimulation of Schaffer collaterals for the three experimental groups before and after a HFS session. by Alejandra Rangel (257878)

“…The HFS train was presented after 15 min of baseline recordings, at the time marked by the dashed line and consisted of five 200 Hz, 100 ms trains of pulses at a rate of 1/s. This protocol was presented six times, at intervals of 1 min. fEPSPs are given as a percentage of the baseline (100%) slope. …”

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx by Sailei Jia (19966413)

“…</p>Conclusion<p>The combination of traditional Chinese medicine and modern medicine has been shown to effectively decrease inflammatory indicators in patients with mild to moderate acute pancreatitis, leading to a reduction in symptom duration and hospitalization period, as well as promoting disease recovery. …”

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx by Sailei Jia (19966413)

“…</p>Conclusion<p>The combination of traditional Chinese medicine and modern medicine has been shown to effectively decrease inflammatory indicators in patients with mild to moderate acute pancreatitis, leading to a reduction in symptom duration and hospitalization period, as well as promoting disease recovery. …”

Table_1_Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts.docx by Jose Manuel Sánchez-Maldonado (11611801)

“…In addition, carriers of the LRRC55_rs717117G allele showed decreased production of IL6 after stimulation of PBMCs with B burgdorferi and E coli bacteria (P=0.00046 and P=0.00044), which suggested a reduced IL6-mediated anti-inflammatory effect of this marker to worsen the response to TNFi. …”

Table_3_Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts.xlsx by Jose Manuel Sánchez-Maldonado (11611801)

“…In addition, carriers of the LRRC55_rs717117G allele showed decreased production of IL6 after stimulation of PBMCs with B burgdorferi and E coli bacteria (P=0.00046 and P=0.00044), which suggested a reduced IL6-mediated anti-inflammatory effect of this marker to worsen the response to TNFi. …”

Table_2_Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts.xlsx by Jose Manuel Sánchez-Maldonado (11611801)

“…In addition, carriers of the LRRC55_rs717117G allele showed decreased production of IL6 after stimulation of PBMCs with B burgdorferi and E coli bacteria (P=0.00046 and P=0.00044), which suggested a reduced IL6-mediated anti-inflammatory effect of this marker to worsen the response to TNFi. …”

Photochromism of 1,2-Bis(2-ethyl-5-phenyl-3-thienyl)perfluorocyclopentene in a Single-Crystalline Phase. Conrotatory Thermal Cycloreversion of the Closed-Ring Isomer by Seiya Kobatake (1628683)

“…The blue solution and single crystal returned colorless by irradiation with visible light (λ > 500 nm) or heating above 100 °C. The bleaching is due to the cycloreversion of <b>1b</b> to <b>1a</b>. …”

Text S1 - The HIV-1 Envelope Transmembrane Domain Binds TLR2 through a Distinct Dimerization Motif and Inhibits TLR2-Mediated Responses by Eliran Moshe Reuven (615575)

“…In this experiment the NBD-labeled TLR2 TMD peptide was added first from a stock solution in DMSO (final concentration 0.1 µM and a maximum of 0.25% (v/v) DMSO) to a dispersion of PC∶Chol LUVs (100 µM) in PBS. …”

Table 1_Combined oven/freeze drying as a cost and energy-efficient drying method for preserving quality attributes and volatile compounds of carrot slices.docx by Zobabalo Progress Mina (20532509)

“…FD carrot slices retained significantly higher levels of β-carotene (11.67–25.96 mg/100 g DM), lycopene (9.91–21.85 mg/100 g DM), total phenolic content (7.12–10.24 mg GAE/100 g DM), and DPPH radical scavenging activity (16.44–19.38 mM AAE/100 g DM) than OD and OD-FD slices. …”

The effect of PKCλ knock-down on hyperglycemia-induced insulin resistance. by Katherine A. Robinson (645068)

“…</b> cells preincubated in 5 mM glucose (IS) vs. 25 mM glucose+0.6 nM insulin (GI-IR) and then stimulated (the black bars) or not (basal) with acute, 100 nM insulin. …”

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx by Chao Zhou (471522)

“…Nonetheless, how organic manure substitution regulates microbial communities to influence soil quality and crop yield remains unclear. </p>Methods<p>A one-year field experiment comprising four organic manure substitution rates (25%, 50%, 75%, and 100%) along with a no-substitution control was conducted. …”

Actuating neuronal activity of Ssdp-expressing neurons alters autism-associated behaviors. by Safa Salim (9186786)

“…(G) Interaction time is significantly decreased in Ssdp^[2082-G4] flies (<i>n</i> = 46–48, Cliff’s Δ = −0.61 [95 CI −0.761, −0.414], <i>p</i> < 0.0001) and Ssdp^[2082-G4] >UAS-GtACR1 flies (<i>n</i> = 40–45, Cliff’s Δ = −0.50 [95 CI −0.679, −0.261], <i>p</i> < 0.0001); however, it is significantly increased in Ssdp^[2082-G4]>UAS-Chrimson flies (<i>n</i> = 42–45, Cliff’s Δ = 0.25 [95 CI 0.00529, 0.478], <i>p</i> = 0.038), compared to their controls. …”

LANA NBs functions as transcription memory. by Tomoki Inagaki (12903779)

Ssdp-positive cells colocalize with neurons and not with glia in Ssdp^[2082-G4] brains. by Safa Salim (9186786)

Z-stack through a mouse kidney in vivo, showing typical renal structures like glomeruli (g), proximal tubules (pt) and extraglomerular capillaries (arrows). by Ina Maria Schießl (288061)

“…<p>Images were acquired with internal detectors and gain and offset of the detectors were maintained during the imaging process. (A) – (F) show layers in 0, 30, 40, 50, 70, and 100 µm depth underneath the kidney surface. …”

DataSheet1_Volume loss during muscle reinnervation surgery is correlated with reduced CMAP amplitude but not reduced force output in a rat hindlimb model.PDF by Alexis L. Lowe (17967446)

“…Surprisingly, neither MR group, with or without volume loss, demonstrated decreased force compared to positive controls. The average force output of reinnervated DMTs, as a fraction of the contralateral LG’s force output, approached 100% for both MR groups, a notable deviation from the 9.6% (±6.3%) force output observed in our negative control group at 7 days post-surgery. …”

Schematic of multiscale biphasic blood flow simulations in the arterial side of the MCA territory. by Grant Hartung (5987810)

Table5_Linkage Disequilibrium and Effective Population Size of Buffalo Populations of Iran, Turkey, Pakistan, and Egypt Using a Medium Density SNP Array.XLSX by Shirin Rahimmadar (11801645)

“…The corrected r² between SNPs decreased with increasing physical distance from 100 Kb to 1 Mb. …”

Image9_Linkage Disequilibrium and Effective Population Size of Buffalo Populations of Iran, Turkey, Pakistan, and Egypt Using a Medium Density SNP Array.PNG by Shirin Rahimmadar (11801645)

“…The corrected r² between SNPs decreased with increasing physical distance from 100 Kb to 1 Mb. …”