Neosartorya glabra polygalacturonase produced from fruit peels as inducers has the potential for application in passion fruit and apple juices by Vanessa Elisa Pinheiro (10424390)

“…The aim of this work was to assess the production of polygalacturonase by the fungus Neosartorya glabra by means of solid-state and submerged fermentation using fruit peel residues as the carbon source, and also apply the enzyme in the clarification and decrease in viscosity of passion fruit and apple juices. …”

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

“…<p><b>A)</b> Heat map generated from the time-lapse fluorescence microscopy movie (10 s intervals) of rat SMCs treated with ET-1 (100 nM) in nominally free extracellular Ca²⁺, showing that the SR depletion wave expands in a near circular fashion in both directions of the scan line (dotted white line). …”

Mouse phrenic nerve hemi diaphragm and bladder strip <i>ex vivo</i> assays. by Mark Elliott (33144)

“…The time required to decrease the contractile strength by 50% (t₅₀) was determined from the fitted curves. …”

Data_Sheet_1_Metabolite Profile, Ruminal Methane Reduction, and Microbiome Modulating Potential of Seeds of Pharbitis nil.docx by Rajaraman Bharanidharan (5635310)

“…A quadratic increase (p = 0.078) in neutral detergent fiber digestibility was also noted, demonstrating that doses < 9% DM were optimal for simultaneously enhancing digestibility and CH₄ reduction. In sacco, a 50% decrease (p = 0.087) in CH₄ coupled with an increase in propionate suggested increased biohydrogenation in the treatment phase. …”

GCP proliferation induced by WNT3 is not dependent on the BMP pathway. by Sandrine L. Anne (489755)

“…<p>(<i>A</i>) WNT3 and BMPs (BMP2, BMP4, BMP6, and BMP7) cooperated to decrease proliferation of GCPs as measured by [³H]-Thymidine incorporation assay. …”

HIV-1 envelope glycoprotein gp41 schematic and structure of the 2F5 antibody-peptide complex. by Javier Guenaga (150719)

“…Residues at the apex of the CDRH3 in magenta (_100ALFGV_100D) were not altered. …”

Table_1_Study on the additional financial burden of breast cancer disease on cancer patients and their families. Financial toxicity in cancer.XLSX by Eduardo J. Fernandez-Rodriguez (18963088)

“…However, after being diagnosed with breast cancer, there is a significant income decrease of 15.91%, resulting in a reduced average annual income of 16785.98 euros. …”

Gonioscopy-assisted transluminal trabeculotomy (GATT) outcomes in eyes with open-angle glaucoma resistant to maximum treatment by Bruno M. de Faria (12684057)

“…A statistically significant difference was observed between overall mean follow-up intraocular pressure and mean preoperative intraocular pressure (p<0.001) in all follow-up visits. …”

<i>In Utero</i> nicotine exposure model and cephalometric analysis of mandible. by E. L. Durham (6837713)

“…Data categorized by sex with mean per exposure indicated with grey bar. Total mandibular length <b>(D)</b> did not vary with nicotine exposure, however, <i>in utero</i> exposure to high dose nicotine decreased the height of the ramus <b>(E)</b> significantly compared to low dose nicotine, perhaps indicating a dose dependent effect. …”

Practical facility-level approaches to reduce the malaria test positivity rate in Oyo State, Nigeria dataset.csv by Esther Oluwayemisi Ayandipo (18777193)

“…(t=9.306, p<0.01 CI=10.73-16.94) At SHF, following the BMMT in September 2021, the microscopy-based TPR declined from 50% in September 2021 to 18% in December 2022. A review of the period from January to December 2021 showed a decrease in TPR from 53%-29%, compared to January to December 2022 with TPR decrease from 25%-31%. …”

Aspirin treatment inhibits osteoclast activities. by Takayoshi Yamaza (67506)

“…(D) RANKL-induced osteoclastogenesis was partially blocked by aspirin treatment at 50 µg/ml as seen a significantly decreased number of TRAP-positive osteoclasts in aspirin treated group (ASP 50). …”

Image_4_The noise is the signal: spatio-temporal variability of production and productivity in high elevation meadows in the Sierra Nevada mountain range of North America.jpeg by Rob Klinger (2917100)

“…<p>There are expectations that increasing temperatures will lead to significant changes in structure and function of montane meadows, including greater water stress on vegetation and lowered vegetation production and productivity. We evaluated spatio-temporal dynamics in production and productivity in meadows within the Sierra Nevada mountain range of North America by: (1) compiling Landsat satellite data for the Normalized Difference Vegetation Index (NDVI) across a 37-year period (1985–2021) for 8,095 meadows >2,500 m elevation; then, (2) used state-space models, changepoint analysis, geographically-weighted regression (GWR), and distance-decay analysis (DDA) to: (a) identify meadows with decreasing, increasing or no trends for NDVI; (b) detect meadows with abrupt changes (changepoints) in NDVI; and (c) evaluate variation along gradients of latitude, longitude, and elevation for eight indices of temporal dynamics in annual production (mean growing season NDVI; MGS) and productivity (rate of spring greenup; RSP). …”

Image_1_The noise is the signal: spatio-temporal variability of production and productivity in high elevation meadows in the Sierra Nevada mountain range of North America.jpeg by Rob Klinger (2917100)

“…<p>There are expectations that increasing temperatures will lead to significant changes in structure and function of montane meadows, including greater water stress on vegetation and lowered vegetation production and productivity. We evaluated spatio-temporal dynamics in production and productivity in meadows within the Sierra Nevada mountain range of North America by: (1) compiling Landsat satellite data for the Normalized Difference Vegetation Index (NDVI) across a 37-year period (1985–2021) for 8,095 meadows >2,500 m elevation; then, (2) used state-space models, changepoint analysis, geographically-weighted regression (GWR), and distance-decay analysis (DDA) to: (a) identify meadows with decreasing, increasing or no trends for NDVI; (b) detect meadows with abrupt changes (changepoints) in NDVI; and (c) evaluate variation along gradients of latitude, longitude, and elevation for eight indices of temporal dynamics in annual production (mean growing season NDVI; MGS) and productivity (rate of spring greenup; RSP). …”

Image_3_The noise is the signal: spatio-temporal variability of production and productivity in high elevation meadows in the Sierra Nevada mountain range of North America.jpeg by Rob Klinger (2917100)

“…<p>There are expectations that increasing temperatures will lead to significant changes in structure and function of montane meadows, including greater water stress on vegetation and lowered vegetation production and productivity. We evaluated spatio-temporal dynamics in production and productivity in meadows within the Sierra Nevada mountain range of North America by: (1) compiling Landsat satellite data for the Normalized Difference Vegetation Index (NDVI) across a 37-year period (1985–2021) for 8,095 meadows >2,500 m elevation; then, (2) used state-space models, changepoint analysis, geographically-weighted regression (GWR), and distance-decay analysis (DDA) to: (a) identify meadows with decreasing, increasing or no trends for NDVI; (b) detect meadows with abrupt changes (changepoints) in NDVI; and (c) evaluate variation along gradients of latitude, longitude, and elevation for eight indices of temporal dynamics in annual production (mean growing season NDVI; MGS) and productivity (rate of spring greenup; RSP). …”

Image_2_The noise is the signal: spatio-temporal variability of production and productivity in high elevation meadows in the Sierra Nevada mountain range of North America.jpeg by Rob Klinger (2917100)

“…<p>There are expectations that increasing temperatures will lead to significant changes in structure and function of montane meadows, including greater water stress on vegetation and lowered vegetation production and productivity. We evaluated spatio-temporal dynamics in production and productivity in meadows within the Sierra Nevada mountain range of North America by: (1) compiling Landsat satellite data for the Normalized Difference Vegetation Index (NDVI) across a 37-year period (1985–2021) for 8,095 meadows >2,500 m elevation; then, (2) used state-space models, changepoint analysis, geographically-weighted regression (GWR), and distance-decay analysis (DDA) to: (a) identify meadows with decreasing, increasing or no trends for NDVI; (b) detect meadows with abrupt changes (changepoints) in NDVI; and (c) evaluate variation along gradients of latitude, longitude, and elevation for eight indices of temporal dynamics in annual production (mean growing season NDVI; MGS) and productivity (rate of spring greenup; RSP). …”

RER1 expression significantly reduces αSyn levels. by Hyo-Jin Park (4233949)

“…(C) αSyn levels in both 1% Triton X-100 and 2% SDS fractions were decreased by RER1 overexpression (*p<0.05, **p<0.01; F_2,9 = 14.02, p = 0.0017) (n = 4/group). …”

Possible Increase in Serum FABP4 Level Despite Adiposity Reduction by Canagliflozin, an SGLT2 Inhibitor by Masato Furuhashi (85555)

“…Treatment with canagliflozin significantly decreased adiposity and levels of fasting glucose and HbA1c but increased average serum FABP4 level by 10.3% (18.0 ± 1.0 vs. 19.8 ± 1.2 ng/ml, P = 0.008), though elevation of FABP4 level after treatment was observed in 26 (66.7%) out of 39 patients. …”

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…<p>A) ACVR2 promoter with map of positioning of MSP primers B) Using a CpG islands search program, we identified the CpG islands within the <i>ACVR2</i> promoter based upon following stringent criteria: ∼CG percentage>55%; observed CpG/expected CpG >0.65; length >500 bp. …”

Supplementary Material for: The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in... by Reuther C. (3593810)

“…The small molecule NVP-CGM097 is a novel MDM2 inhibitor. We investigated MDM2 inhibition as a target in neuroendocrine tumor cells in vitro. …”

Data_Sheet_1_Transcriptome and Proteomics Analysis of Wheat Seedling Roots Reveals That Increasing NH4+/NO3– Ratio Induced Root Lignification and Reduced Nitrogen Utilization.DOCX... by Dongqing Yang (675454)

“…However, the mechanisms underlying the response of wheat seedling roots to changes in NH₄⁺/NO₃^– ratio remain unclear. In this study, we investigated wheat growth, transcriptome, and proteome profiles of roots in response to increasing NH₄⁺/NO₃^– ratios (N_a: 100/0; N_r1: 75/25, N_r2: 50/50, N_r3: 25/75, and N_n: 0/100). …”