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nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
b decrease » _ decrease (Expand Search), b1 decreased (Expand Search), _ decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
b decrease » _ decrease (Expand Search), b1 decreased (Expand Search), _ decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Aging Mice Show a Decreasing Correlation of Gene Expression within Genetic Modules
Published 2009“…We found that computationally identified targets of the NF-<em>Κ</em>B transcription factor decrease expression correlation with age. …”
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<i>csrnp1a</i> knockdown decreases the number of blood cells in circulation.
Published 2013“…The injection of <i>csrnp1a</i> morpholino produces a dramatic reduction of blood cells in 34% of the injected embryos (n = 16/47) at 33 hpf (A, B, C, F, G) which is reverted at 48 hpf (D, E) (all are lateral views, anterior to the left). …”
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TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment.
Published 2016“…<p>We examined mRNA expression of TGFβ1 and RASAL1 by qPCR and protein expression by Western blotting under normoxic (21%O<sub>2</sub>) and hypoxic conditions (1%O<sub>2</sub>). <b>A.</b> qPCR showed an apparent increase in TGFβ1 mRNA expression in cells subjected to hypoxia after 6 hours; fold change in gene expression was 1.37+/-0.16. …”
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Anti-inflammation decreases promoter methylation and restores <i>p21</i> expression.
Published 2013“…<p>(A) Decreased CpG 16 methylation of p21 promoter from forestomach samples of <i>Tgfbr2<sup>fspKO</sup></i> mice treated with Celecoxib (n = 3). …”
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DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption.
Published 2020“…WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”
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Acute Snail knockout decreases the numbers of neural precursors and neurons in the embryonic cortex.
Published 2014“…Arrows indicate EGFP-negative cells with robust nuclear Snail immunoreactivity, and arrowheads denote EGFP-positive cells with decreased Snail staining. Scale bar 20 µm. (B) Fluorescence micrographs of coronal sections through E16/17 control or Cre-electroporated cortices immunostained for EGFP (green). …”
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PS1 downregulation in new neurons decreases dendritic arborization and spine density.
Published 2015“…<b>C, D</b>. PS1 downregulation results in decreased number of spines <b>(C)</b> as a function of increasing distance from the soma (two-way ANOVA (treatment and distance from soma) F<sub>(treatment)1,60</sub> = 13.10, P<0.001, F<sub>(distance)19,60</sub> = 3.18, P<0.001) and mean spine density <b>(D)</b> (unpaired t-test, *P<0.05). …”
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