Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Bouquin et al. - High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…The differences persisted as follows: reduction of stroke volume in six out of six (6/6) between-quartile comparisons (p<0.001), decrease in cardiac output (p<0.001) and increase in heart rate in 5/6 comparisons (p<0.001), change in systemic vascular resistance in 3/6 comparisons (p<0.001), change in aortic systolic blood pressure in 1/6 comparisons (p=0.043), and change in aortic diastolic blood pressure in none (p=0.266). …”

Table 1_Predicting the potential distribution of Corylus heterophylla in China under future climate change using an optimized MaxEnt model.docx by Jingyu Wang (292122)

“…</p>Discussion<p>These findings provide a scientific basis for conserving and sustainably utilizing C. heterophylla under climate change.…”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Classes of errors and gaps in BOLD metadata. by Frederik Stein (22146203)

“…However, this issue may now be mitigated, as the BOLD v5 ID engine default mode exclusively employs published data. …”

Climate Impacts on Extreme Energy Consumption of Different Types of Buildings by Mingcai Li (731610)

“…No significant variations were found for the days of extreme energy consumption for commercial building, although a decreasing trend in extreme heating energy consumption. …”

Standard curves for the 11 inorganic elements. by Xijia Jiu (17403990)

“…The results showed that dormancy release may have occurred following the decrease in palmitic acid and linoleic acid content in the seeds and the increase in 2,3-dihydro-3,5-dihydro-6-methyl-4 (h)-pyran-4-one content in the endosperm. …”

Microwave digestion procedure. by Xijia Jiu (17403990)

“…The results showed that dormancy release may have occurred following the decrease in palmitic acid and linoleic acid content in the seeds and the increase in 2,3-dihydro-3,5-dihydro-6-methyl-4 (h)-pyran-4-one content in the endosperm. …”

Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Image 1_Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats.pdf by Silvia Granata (2678077)

“…Furthermore, inactivation of key androgenic enzymes, such as 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, together with decreased testosterone synthesis suggest a potential impairment of male gonadal function.…”

Data_Sheet_2_Quercetin positively affects gene expression profiles and metabolic pathway of antibiotic-treated mouse gut microbiota.PDF by Wei Mi (812194)

“…<p>Quercetin has a wide range of biological properties that can be used to prevent or decrease particular inflammatory diseases. …”

Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Treatment with the Proteasome Inhibitor MG132 during the End of Oocyte Maturation Improves Oocyte Competence for Development after Fertilization in Cattle by Jinyoung You (121636)

“…Another protein decreased by MG132, CDK5, can lead to apoptosis if aberrantly activated and one protein increased by MG132, P4HB, is anti-apoptotic. …”

Bouquin et al. - High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…The differences persisted as follows: reduction of stroke volume in six out of six (6/6) between-quartile comparisons (p<0.001), decrease in cardiac output (p<0.001) and increase in heart rate in 5/6 comparisons (p<0.001), change in systemic vascular resistance in 3/6 comparisons (p<0.001), change in aortic systolic blood pressure in 1/6 comparisons (p=0.043), and change in aortic diastolic blood pressure in none (p=0.266). …”

DataSheet_2_Highlighting the novel effects of high-intensity interval training on some histopathological and molecular indices in the heart of type 2 diabetic rats.docx by Mohammad Rami (15650177)

“…This research showed that diabetes disorder increases the levels of B-catenin and c-Myc proteins and causes a decrease in the expression of GSK3B and Bcl-2 proteins. …”

DataSheet_1_Deep mowing rather than fire restrains grassland Miscanthus growth via affecting soil nutrient loss and microbial community redistribution.docx by Zhuxin Mao (12578495)

“…After harvest, deep mowing induced the greatest effect on biomass among all treatments, as it induced a 5.2-fold decrease in dry biomass relative to the control. …”

Dietary Lactic Acid Bacteria Modulate Yolk Components and Cholesterol Metabolism by Hmgr Pathway in Laying Hens by Q Deng (10447343)

“…In liver, high LAB downregulated (p<0.05) mRNA expression of serine/threonine kinase 11 (STK11), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), AMP-activated protein kinase catalytic subunit (PRKAA1, 2), and protein phosphatase catalytic subunits (PPP2CA, PPP2CB and PPP3CA) by 49.5 to 175.4%. …”