Showing 521 - 540 results of 225,269 for search '(( 50 ((mean decrease) OR (teer decrease)) ) OR ( 10 ((nm decrease) OR (a decrease)) ))', query time: 1.70s Refine Results
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    IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

    Published 2016
    “…Among the three compounds, only MK204 can make a strong halogen bond with the protein (−4.4 kcal/mol, using QM calculations), while presenting the lowest desolvation cost among all the series, translated into the most selective and inhibitory potency AKR1B10 (IC<sub>50</sub> = 80 nM). …”
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    Fig 3 - by Hiroyuki Matsuta (13250169)

    Published 2022
    Subjects:
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    Progesterone decreased Henkel 100-induced responses in a dose-dependent manner in the OE of female mice. by Ninthujah Kanageswaran (683924)

    Published 2016
    “…(E) Relative reduction in peak response to Henkel 100 after progesterone preincubation at different concentrations (0.1 nM: 11.9 ± 2.1% (n = 3), 1 nM: 18.4 ± 3.1% (n = 3), 10 nM: 22.0 ± 11.4% (n = 4), 100 nM: 31.4 ± 7.3% (n = 4), 1 μM: 37.9 ± 2.2% (n = 4), and 10 μM: 48.8 ± 2.1% (n = 4)). …”
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