Showing 921 - 940 results of 31,189 for search '(( 50 ((mean decrease) OR (we decrease)) ) OR ( 100 ((nm decrease) OR (a decrease)) ))', query time: 0.93s Refine Results
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    Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity by Elizabeth S. Childress (2116453)

    Published 2017
    “…Surprisingly, combining features of reported SphK1 inhibitors generated SphK1/2 dual inhibitor <b>20l</b> (SLC4011540) (hSphK1 <i>K</i><sub>i</sub> = 120 nM, hSphK2 <i>K</i><sub>i</sub> = 90 nM) and SphK2 inhibitor <b>20dd</b> (SLC4101431) (<i>K</i><sub>i</sub> = 90 nM, 100-fold SphK2 selectivity). …”
  15. 935

    C2GnT1 gene knockdown decreases C2-O-sLe<sup>X</sup> glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

    Published 2013
    “…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”
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    Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

    Published 2013
    “…</p><p>Results</p><p>The mean value of pcUACR at 12-week and 16-week visits (primary outcome) was decreased more in the Tac group compared to the control group (–52.0±26.4 vs –17.3±29.3%, p = 0.001). …”