Supporting Role for GTPase Rab27a in Hepatitis C Virus RNA Replication through a Novel miR-122-Mediated Effect by Tzu-Chun Chen (787255)

“…However, the abundance of HCV RNA carrying mutations on both miR-122-binding sites and whose stability was supported by ectopically expressed miR-122 mimetics with compensatory mutations also decreased in Rab27a-depleted cells. This result indicates that the effect of Rab27a depletion on HCV RNA abundance does not depend on the formation of 5’ terminal HCV/miR-122 RNA complexes, but that miR-122 has a Rab27a-dependent function in the HCV lifecycle, likely the downregulation of a cellular inhibitor of HCV gene expression. …”

<i>Rpl5</i> mutant ES cells exhibit a p53-independent G2 cell cycle arrest. by Sharon A. Singh (524066)

“…In contrast, the cell cycle profile of the <i>Rpl5</i> mutant ES cells exhibited a three-fold increase in the G2 phase with a concomitant decrease in the G1 and S phases, consistent with a delayed G2 phase transition (A, C) (three independent pooled experiments). …”

Next-generation sequencing analyses of parental and mutant MeV stocks documenting the stability of the introduced mutations. by Lorellin A. Durnell-Bettis (22656332)

Table_5_Evidence of a Causal Relationship Between Vitamin D Status and Risk of Psoriasis From the UK Biobank Study.XLSX by Yan Zhang (8098)

“…</p>Results<p>During a median follow-up of 10.99 years, we identified 2,856 participants with incident psoriasis. …”

miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage by Huidan Deng (7330031)

“…Therefore, we conducted a preliminary study on the mechanisms of ssc-miR-221-5p in soybean 7S globulin-injured IPEC-J2 cells. …”

Image_5_Rice OseIF6.1 encodes a eukaryotic translation initiation factor and is essential for the development of grain and anther.jpeg by Hongming Guo (13166058)

Supplemental Figures 1-5 from LEF1 Targeting EMT in Prostate Cancer Invasion Is Regulated by miR-34a by Jiaqian Liang (15079825)

“…<p>Supplemental Figures 1-5. Supplemental Figure 1. Expression levels of miR-34a, miR-1260, miR-206, miR-93, miR-324-3P andmiR-324-5P in four (LNCaP, LNCaP-LEF1, LNCaP-AI, LNCaP-AILEF1shRNA) PCa cell lines by real time qRT-PCR. …”

Relative transcript levels of <i>CitSus</i>1-6 in mature leaves in response to dehydration (A) and in fruit segment membrane (B) and juice sacs (C) in response to mild drought stre... by Mohammad Zahidul Islam (664963)

Image_5_Sinoatrial Node Structure, Mechanics, Electrophysiology and the Chronotropic Response to Stretch in Rabbit and Mouse.TIF by Eilidh A. MacDonald (9154475)

Table_5_Risk Factors for Brain Metastases in Patients With Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.docx by Haiyan Zeng (3753130)

“…Eligibility criteria: studies reporting detailed BM data with an adequate sample size (randomized clinical trials [RCTs]: N ≥50; non-RCTs: N ≥100) in patients with SCLC. We summarized the reported risk factors and performed meta-analysis to estimate the pooled hazard ratios (HR) if enough qualified data (i.e., two or more studies; the same study type; the same analysis method; and HRs retrievable) were available. …”

Atorvastatin sensitivity correlates with blunted Akt phosphorylation in response to EGF. by Colin H. Beckwitt (2037196)

IL-18-induced cell death is partially inhibited by inhibitors of caspase-1 and caspase-3. by Ossama Allam (5043434)

Clostridium difficile toxins or infection induce upregulation of adenosine receptors and IL-6 with early pro-inflammatory and late anti-inflammatory pattern by D.A. Foschetti (10461345)

Non-Pneumatic Anti-Shock Garment (NASG), a First-Aid Device to Decrease Maternal Mortality from Obstetric Hemorrhage: A Cluster Randomized Trial by Suellen Miller (294598)

“…We hypothesized the NASG group would have a 50% reduction in adverse outcomes.…”

Detection of epistasis is rescued by simultaneous analysis of multiple independently-evolved populations. by Gabriele Pedruzzi (5753792)

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Table_5_Balance Adaptation While Standing on a Compliant Base Depends on the Current Sensory Condition in Healthy Young Adults.DOCX by Stefania Sozzi (9193071)

DataSheet1_Potential causal associations of PM2.5 and osteoporosis: a two-sample mendelian randomization study.docx by Yi Zhang (9093)

“…</p><p>Results: The results indicated that PM2.5 was not correlated with a decrease in FN-BMD (β: −0.305, 95%CI: −0.762, 0.153), LS-BMD (β: 0.134, 95%CI: −0.396, 0.666), FA-BMD (β: -0.056, 95%CI: −1.172,1.060), and HE-BMD (β: −0.084, 95%CI: −0.261,0.093). …”

Image_1_A highly susceptible hACE2-transgenic mouse model for SARS-CoV-2 research.PDF by Gang Liu (81776)

“…Overexpression of hACE2 did not pose a significant effect on weight growth. After SARS-CoV-2 inoculation, mice showed obvious viral replication and production of inflammation within 7 days, with a gradual decrease in body weight until death. …”

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”