The expression of bile acid Receptor TGR5 in Adipose Tissue in Diet-induced obesity mice حسب Ahmed, Sumaya

"…There was significant downregulation of TGR5 gene expression level in obese (DIO) mice and remarkable upregulation of TGR5 gene expression after successful weight loss in DIO mice treated with SFN in time dependent manner at 1 weeks and 4 weeks of ip applications. In conclusion, obesity is associated with decrease in expression of TGR5 in different fat depots and treatment with anti-obesity drug (Sulforaphane) causes stepwise upregulation of TGR5 gene expression in epididymal white adipose tissue parallel stepwise decrease in body weight. …"
احصل على النص الكامل
احصل على النص الكامل

The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets حسب Cenciarelli, Carlo

"…In the current study, we assessed the effects of Hes1-targeted shRNA, a Notch1 gene target, specifically on GBM CSC refractory to GSI-X. …"
احصل على النص الكامل

Mechanism of GaAs surface sulfidation حسب Al Marri, M.J.

"…Furthermore, the intensity of the S - O bond (S 2p at 169.1 eV) decreased with time, presumably due to arsenic sulfate dissolution. …"
احصل على النص الكامل

A Reverse MultipleChoice Based mLearning System حسب Karkar, AbdelGhani

احصل على النص الكامل
احصل على النص الكامل

Structural, wear and thermal behaviour of Cu–Al2O3–graphite hybrid metal matrix composites حسب Mittal, P.

"…Copper matrix composites with Al2O3–graphite reinforcement (0.5-0.5, 1.0-1.0, 1.5-1.5 and 2.0-2.0 wt%) were prepared by stir casting process. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

احصل على النص الكامل
احصل على النص الكامل

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

"…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …"
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chemical characterization and evaluation of antimicrobial and cutaneous wound healing potentials of gold nanoparticles using Allium saralicum R.M. Fritsch حسب Hu, X.

"…The MIC and MBC of AuNPs against all bacteria were in the ranges 1–4 mg/ml and 2–8 mg/ml, respectively. The MIC and MFC of AuNPs against all fungi were in the ranges 1–4 mg/ml and 2–4 mg/ml, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
احصل على النص الكامل
احصل على النص الكامل

Synthesis and characterisation of Co2+-incorporated ZnO nanoparticles prepared through a sol-gel method حسب Ba-Abbad, Muneer M.

"…A hexagonal wurtzite-phase structure of Co2+-doped ZnO was observed, with a slight decrease in particle size as the Co2+ doping concentration increased. …"
احصل على النص الكامل
احصل على النص الكامل

Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

"…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …"
احصل على النص الكامل
احصل على النص الكامل

MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …"
احصل على النص الكامل

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Synthesis and characterization of electrically conducting copolymers of poly(aniline-co-o-iodoaniline) حسب Waware, Umesh S.

احصل على النص الكامل
احصل على النص الكامل

Intercalation of ionic liquids into bentonite: Swelling and rheological behaviors حسب Nasser, M. S.

احصل على النص الكامل
احصل على النص الكامل

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

احصل على النص الكامل
احصل على النص الكامل