Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Analysis of Y dLGN cells whose percentage of response in burst was less than 40–50%. by Nelson Espinosa (356237)

“…<p>rTMS@1Hz increased the percentage of spikes in burst <i>(</i><b><i>A</i></b><i>)</i> and consequently decreased tonic spikes <i>(</i><b><i>B</i></b><i>).…”

The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity by Paola Larghi (131929)

“…We propose that nuclear accumulation of the p50 NF-κB subunit in DC, as occurring during lipopolysaccharide-driven maturation, is a homeostatic mechanism tuning the balance between uncontrolled activation of adaptive immunity and immune tolerance.…”

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3 by Chia-Ling Wu (114083)

“…<em>Trim63 (MuRF1)</em>, <em>Fbxo32</em> (<em>MAFbx</em>), <em>Ubc</em>, <em>Ctsl</em>, <em>Runx1</em>, <em>Tnfrsf12a</em> (Tweak receptor), and Cxcl10 (<em>IP-10</em>) showed increased Bcl-3 binding to κB sites in unloaded muscle and thus were direct targets of Bcl-3. p50 binding to the same sites on these genes either did not change or increased, supporting the idea of p50:Bcl-3 binding complexes. p65 binding to κB sites showed decreased or no binding to these genes with unloading. …”

Myosin phosphatase and RhoA-activated kinase modulate neurotransmitter release by regulating SNAP-25 of SNARE complex by Dániel Horváth (4015034)

“…Inhibition of PP1 with tautomycetin increased, whereas inhibition of ROK by H1152, decreased the phosphorylation of SNAP-25 at Thr138 in B50 cells, in cortical synaptosomes, and in brain slices. …”

LD- and haplotype-based measures of epistasis identify a narrow time window of epistasis detectability. by Gabriele Pedruzzi (5753792)

miR expression after 24 hours of 50% nutrient restriction in HTR8 trophoblast cells. by Shanthie Thamotharan (3992894)

Recommendations of no-fly zones for the colonies of common terns, Sandwich terns, black headed gulls, herring gulls and lesser black-backed gulls, great cormorants and Eurasian spo... by Estefania Velilla (22566709)

Lovastatin treatment decreases ICAM-1 and CD11b expression and vascular permeability and induce HMOX-1 expression in the brains of mice with CM. by Patricia A. Reis (109310)

TG6-44 treatment leads to a decrease in NP-positive cells and altered expression patterns of NP in A/X31 infected THP-1 cells. by Juan A. De La Cruz (11154187)

MRPP A-statistics from pairwise comparisons plot distance classes for lichen, vascular plant and bryophyte communities. by Peter N. Neitlich (4034300)

Subjects:

The differences between WKY and SHR responses to betaine. by Izabella Mogilnicka (13965422)

Effects of betaine on diuresis [μl/min/g k.w.], HR [bpm] and MABP [mmHg] in anesthetized Spontaneously Hypertensive rats and Wistar Kyoto normotensive rats. by Izabella Mogilnicka (13965422)

Nonmetric multidimensional scaling ordination of lichen plots at distances 10 m through 4000 m from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects:

Effectiveness of E cytotoxicity presented as a half maximal growth inhibitory concentration (CC₅₀). by Anna Kalota (7415)

Contemporary mean inundation fraction in the Amazon basin. by Nic Gedney (19762301)

Area estimates in CAKR by percentage of the mean LSR of the 3000–4000 m distance class (41.9) according to the posterior predictions model. by Peter N. Neitlich (4034300)

Subjects:

SHIP-1 PRD region is necessary and sufficient to decrease NOD2-induced NF-κB activity. by Claude Condé (150801)

Fig 7 - by Finn Egil Skjeldestad (7821716)

Subjects:

Proteasome inhibition impairs radiation-induced DNA double strand break (DSB) repair by decreasing homologous recombination. by Kyle R. Cron (455028)