Macrophage migration inhibitory factor antagonist (p425) ameliorates kidney histopathological and functional changes in diabetic rats by Jamal Khalilpour (6302258)

“…The aim of the present study was to investigate the renal effects of MIF inhibition in a diabetic experimental model. Methods: Eighteen male Wistar rats (230 ± 20 g) were divided into three groups: 1) control, 2) diabetic (STZ, 50 mg/kg, dissolved in saline, ip), 3) diabetic + MIF antagonist (p425, 1 mg/kg per day, ip, on the 21th day, for 21 consecutive days). …”

Enhancing 7-dehydrocholesterol suppresses brain ferroptosis and tissue injury after neonatal hypoxia-ischemia by Thiago C. Genaro-Mattos (16385144)

“…Animals were injected with 0.2 mg/kg of CAR as described in Figure 5A. 7-DHC-derived oxysterols DHCEO and ep7DHC were not detected (NC) in the Sham+vehicle or HIBI+vehicle groups but were detected in both CAR groups. …”

GO analysis of genes differentially expressed in the SF brain. by Yasuhiko Murata (165491)

Synaptic transmission at cortico-LA synapses is affected by the absence of αGDI. by Veronica Bianchi (186711)

“…(<b>C₂</b>) For each stimulation intensity a ∼60% decrease of EPSC size is observed in <i>Gdi1</i>-null mice. …”

GO terms for genes differentially expressed in the SF eye. by Yasuhiko Murata (165491)

Effect of stoichiometry if the subnetworks are used. by Mehdi B. Hamaneh (7124363)

Data_Sheet_1_Smoking Prevalence, Patterns, and Cessation Among Adults in Hebei Province, Central China: Implications From China National Health Survey (CNHS).docx by Huijing He (3687388)

“…In male participants, the daily cigarette consumption was 16.61, and the mean age of smoking initiation was 20.95, decreasing with birth year (27.50 in people born before 1946 vs. 17.9 for those born after 1985, p for trend < 0.001). …”

The synaptic facilitation and its Ca²⁺-dependence are significantly reduced in footshock stressed rats and the effect is efficiently prevented by desipramine pre-treatme... by Laura Musazzi (242410)

“…<p>A) Specimen paired-pulse eEPSCs at increasing Ca²⁺ concentrations were obtained in vehicle-treated (CNT) and subjected to FS-stress (Stress) rats by stimulating layer V at a time interval of 50 ms and recording from pyramidal neurons. …”

Anti-correlation functional profiling identifies relevant miRNA-target interactions, including miR-150 repression of p53, that regulate MV4-11 cell line growth. by Jared Wallace (410659)

Low levels of dehydroepiandrosterone sulfate are associated with the risk of developing cardiac autonomic dysfunction in elderly subjects by Marina de Paiva Lemos (4704679)

“…A positive correlation between lower serum concentrations of DHEA-S and attenuated variance of HRV (r = 0.47, p = 0.031), as well as lower serum concentrations of DHEA-S and decreased parasympathetic modulation of HRV (r = 0.54, p = 0.010), were found. …”

Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice by Janeen H. Trembley (644906)

“…The sub-50 nm size TBG nanocapsule (s50-TBG) is a slightly negatively charged, uniform particle of 15 - 20 nm size which confers protection to the nucleic acid cargo. …”

Incorporation of 8-oxo-dG, but not 5-OH-dC, reduces the Tm of ASO:DNA and ASO:RNA duplexes. by Margit Mutso (748843)

“…<p><b>(A)</b> Structures of 8-oxo-dG, its zwitterionic (minor) form and 5-OH-dC (common and minor forms). …”

Hypoxia-induced pulmonary remodeling. by Yuko Shirota (4351867)

“…Group1 mice showed a significant decrease in normal but increase in fully remodeled arterial walls. …”

Deficiency of tau protects against age-dependent neurodegeneration and memory loss measured by deficits in spontaneous alternations in AICD-Tg mice. by Kaushik Ghosal (244754)

“…<p>A. AICD-Tg mice exhibit decreased working memory as measured by deficits in spontaneous alternations at older ages. …”

Time series of simulated harvest rate, harvest, cumulative harvest, and example harvest control rules related to climate impacts on carrying capacity and productivity. by Jameal F. Samhouri (10136090)

“…The bottom panels show the harvest control rule when a climate impact causes carrying capacity and productivity to decrease (g) or increase (h), and harvest is managed using either a fixed or climate adaptive strategy (at two example time points, years 25 and 50). …”

Time series of simulated harvest rate, harvest, cumulative harvest, and example harvest control rules related to climate impacts on productivity. by Jameal F. Samhouri (10136090)

“…The bottom panels show the harvest control rule when a climate impact causes productivity to decrease (g) or increase (h), and harvest is managed using either a fixed or climate adaptive strategy (at two example time points, years 25 and 50). …”

Time series of simulated harvest rate, harvest, cumulative harvest, and example harvest control rules related to climate impacts on carrying capacity. by Jameal F. Samhouri (10136090)

“…The bottom panels show the harvest control rule when a climate impact causes carrying capacity to decrease (g) or increase (h), and harvest is managed using either a fixed or climate adaptive strategy (at two example time points, years 25 and 50). …”

Astrocyte activation by GA was sufficient to induce neuronal death through soluble factors. by Silvia Olivera-Bravo (349736)

“…Scale bar: 50 µm. <b>B:</b> Counting of striatal neurons maintained in culture for 24 h with CM-C or increasing dilutions of CM-GA or vehicle. …”

Chn over-expression increases lamellocyte number. by Martin Stofanko (236917)

“…<p>Chn overexpression decreases (<b>A</b>,<b>E</b>) sessile (asterisk) and (<b>B</b>,<b>F</b>) circulating plasmatocyte numbers. …”

Time course of activity levels in middle-aged female mice. by David R. Bonsall (813770)

“…(B) Similar reductions in wheel-running activity were seen in mice given 50ng IL-1β i.c.v. (n = 5). (C) The total number of wheel-running sessions during the dark period was reduced by IL-1β, with increased fatigability (measured as decreased bout duration) (D) seen during each session as compared to baseline levels. …”