Multifunctional Hybrid Compounds Derived from 2‑(2,5-Dioxopyrrolidin-1-yl)-3-methoxypropanamides with Anticonvulsant and Antinociceptive Properties by Michał Abram (4490902)

“…Such hybrids demonstrated effectiveness in two of the most widely used animal seizure models, namely, the maximal electroshock (MES) test and the psychomotor 6 Hz (32 mA) seizure models. Compound <b>33</b> showed the highest anticonvulsant activity in these models (ED₅₀ MES = 79.5 mg/kg, ED₅₀ 6 Hz = 22.4 mg/kg). …”

PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

All Ca_V3.3 variants left-shift the voltage dependence of inactivation. by Yousra El Ghaleb (22075892)

Subjects:

<i>T</i>_m values of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

Solubilized P, dry biomass, pH and titratable acidity in NBRIP medium with Araxá RP (3 g L⁻¹) as the only P source, Ca₃(PO₄)₂ (5 g L<sup... by Ubiana de Cássia Silva (643658)

“…</p><p>Solubilized P, dry biomass, pH and titratable acidity in NBRIP medium with Araxá RP (3 g L⁻¹) as the only P source, Ca₃(PO₄)₂ (5 g L⁻¹) + F⁻ (50 mg L⁻¹), or Ca₃(PO₄)₂ (5 g L⁻¹) after the cultivation of <i>Aspergillus niger</i> FS1 mutants and the wild type for 60 h at 32°C and 160 rpm.…”

Catalytic fold of WT PARG1 C1-GAP domain for RhoA interaction. by Zen Kouchi (14898435)

Fig 5 - by Pierre Bauvin (18154818)

Hypoxia induced decreases in dendritic spine density, length, soma size and volume of the apical and basal branches of CA1 and CA3 pyramidal neurons. by Chun-Sing Lam (695733)

Mutation of four arginine residues in P34 leads to a decrease in binding between P34 and L5. by Anyango D. Kamina (4034165)

Lovastatin treatment decreases ICAM-1 and CD11b expression and vascular permeability and induce HMOX-1 expression in the brains of mice with CM. by Patricia A. Reis (109310)

Environmental Enrichment on <i>Mecp2^−/y</i>-EE mice induces a decrease in the expression of a set of synaptic plasticity-related genes. by Bredford Kerr (363408)

Fig 5 - by Melissa A. Hill (13170105)

NBCe1 and NBCe2 protein and mRNA expression in hRPTCs carrying wild-type (WT) or homozygous variant (HV) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<b>D) <i>SLC4A4</i> mRNA.</b> <i>SLC4A4</i> mRNA is decreased following an increase in intracellular sodium (monensin, 1 μmol/L, 24 h) (↑Na⁺) only in WT <i>SLC4A5</i> hRPTCs (N = 9, *P<0.05 vs. …”

Fig 13 - by Jianbo Jia (717814)

“…The simulation results show that for steps of 1mm, 2mm and 3mm height, the optimal polyline angle is concentrated in the range of 10°-11°, in which the Angle of 10.5° has a good performance against the steps of three heights. …”

Levels of resistance of alphavirus RNA translation to IFN-β is determined by 5’UTRs of their genomes. by Josephine M. Reynaud (732822)

Genes involved in lipid metabolism that are differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Genes involved in carbohydrate metabolism differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

The differences between WKY and SHR responses to betaine. by Izabella Mogilnicka (13965422)

Effects of betaine on diuresis [μl/min/g k.w.], HR [bpm] and MABP [mmHg] in anesthetized Spontaneously Hypertensive rats and Wistar Kyoto normotensive rats. by Izabella Mogilnicka (13965422)

related to Fig 5: Glycolysis critically regulates the acidification of phagosome and the assembly of v-ATPase complex. by Saray Gutiérrez (11473528)