Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV‑1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutan... by Sheng Han (419184)

“…The antiviral activity of this compound was much higher than those of ETR and EFV against the WT, E138K, and K103N variants (EC₅₀ = 3.4, 4.3, and 3.6 nM, respectively), and the cytotoxicity was decreased while the selectivity index (SI) was increased. …”

IPF fibroblasts are desensitized to collagen rich matrix induced cell death in the presence of 3MA or CQ. by Richard Seonghun Nho (54078)

“…Shown is the % decrease in control and IPF fibroblasts in the presence of autophagic inhibitors on polymerized collagen (the viable IPF and control fibroblasts on collagen matrix in the absence of inhibitors (0 µM) are considered as 100% viable cells). …”

Comparison of the fraction of cooperators for different behavioral updating. by Xiaochen He (455300)

“…<p>The simulation is carried out 10 times on a random network consisting of 100 nodes with average network connectivity 〈<i>k</i>〉 = 4. …”

The influence of heparin on histone induced aggregation of low-density lipoprotein. by Alan D. Pemberton (217101)

“…<b>C:</b> Inclusion of varying concentrations of low molecular weight heparin (LMWH) and unfractionated heparin (UFH) with LDL (1.25 mg/ml) and histone (0.25 mg/ml) caused a general decrease in protein aggregation, relative to uninhibited incubations. …”

<i>mecR2</i> is essential for the optimal expression of β-lactam resistance in strains with functional <i>mecI-mecR1</i> regulatory locus. by Pedro Arêde (149569)

“…<p>(A) Deletion of <i>mecR2</i> from the chromosome of prototype epidemic strains USA100, USA200 and USA600 harboring SCC<i>mec</i> type II causes a decrease on the resistance level to oxacillin, which can be reverted upon complementation with <i>mecR2</i> expressed from an inducible promoter (<i>spac</i>::<i>mecR2</i>) in the presence of the inducer (IPTG 100 µM). …”

Artichoke extracts with potential application in chemoprevention and inflammatory processes by Rosana Rotondo (12653532)

“…Inhibition of SH-SY5Y cells proliferation by Gauchito and Guri leaf extracts (8 µg/mL) was higher than 50 %. The leaf extracts of the same cultivars showed an inhibitory effect on human interferon IFN-I, decreasing its activity 50% at 40 µg/mL. …”

Transformation of skin fibroblasts into hematopoietic cells that engraft in NOD-Scid mice. by David M. Harris (216744)

“…Right panel: Morphological analysis of transfected skin fibroblasts cytospun onto glass slides and stained with Wright-Giemsa demonstrated typical hematologic cell characteristics: (a) cultured untreated skin fibroblasts (X 100 magnification); (b) immature myeloid and lymphoid blasts (insert shows TdT nuclear immunofluorescent staining). …”

MSC staining in vitro. by Luke J. Mortensen (477665)

“…Despite a small decrease in viability from the unstained control (p<0.05, Tukey’s HSD), there was minimal difference between viability of cells after staining as measured by MTS (c). …”

Magnesium oxide use and reduced risk of dementia: a retrospective, nationwide cohort study in Taiwan by Nian-Sheng Tzeng (427571)

“…</p> <p><b>Conclusions:</b> The patients who used MgO had a decreased risk of developing dementia. …”

Knockdown of cyclin D1 and Ets1 suppressed the proliferation, migration, and invasion of gastric cancer cells <i>in vitro</i>. by Liduan Zheng (182440)

“…<p><b>A</b>, transfection of si-CCND1 (100 nmol/L) into gastric cancer SGC-7901 and AGS cells resulted in decreased expression of cyclin D1 and its downstream target pRB than those transfected with scramble siRNA (si-Scb, 100 nmol/L). …”

Data_Sheet_1_Long-Term Changes in the Water Mass Properties in the Balearic Channels Over the Period 1996–2019.docx by Manuel Vargas-Yáñez (9405440)

“…Nevertheless, combining CTD data with temperature data from the oceanographic station at L’Estartit and simulated data from the NCEP/NCAR reanalysis, it can be established that the Atlantic Water increased its temperature at a rate of 2.1–2.8°C/100yr and likely its salinity at a rate of 0.6/100yr. …”

Data_Sheet_1_Long-Term Changes in the Water Mass Properties in the Balearic Channels Over the Period 1996–2019.docx by Manuel Vargas-Yáñez (9405440)

“…Nevertheless, combining CTD data with temperature data from the oceanographic station at L’Estartit and simulated data from the NCEP/NCAR reanalysis, it can be established that the Atlantic Water increased its temperature at a rate of 2.1–2.8°C/100yr and likely its salinity at a rate of 0.6/100yr. …”

Temperature and moisture content effects on compressive strength parallel to the grain of paricá by Manuel Jesús Manríquez Figueroa (12833842)

“…The specimens from HT and WS samples were tested at a temperature range from 20 to 230 ºC and 20 to 100 ºC, respectively. …”

Immunohistochemical examination of NF-kβ p65 in liver tissue. by Rasha E. Mostafa (11767721)

“…<p>Liver tissues, immunohistochemically stained with anti- NF-kβ <b>p65</b> antibodies, from <b>(A)</b> sham-operated rat, <b>(B)</b> ovariectomy-control rat showing no expression of NF-kβ in the liver tissue, <b>(C)</b> TAA-control rat showing the strong positive result of the stain especially around the central veins, <b>(D)</b> rat treated with <i>panax ginseng</i> (100 mg/kg) showing a mild decrease in positively stained cells, and <b>(E)</b> rat treated with <i>panax ginseng</i> (300 mg/kg) showing a remarkable decrease in the positive result <b>(NF-kβ p65 immunohistochemical staining)</b>.…”

Effect of RNAi depletion of selected hits on lipid droplet formation and TOR pathway activation. by Vangelis Kondylis (229490)

“…(<b>C</b>) Number of lipid droplets per equatorial confocal cell section quantified and expressed as percentage normalised to the respective value in mock-treated cells, which was set as 100%. Red and blue columns indicate proteins whose depletion leads to a significant decrease or increase in the number of lipid droplets (marked with double asterisk; p<0.05). …”

Table1_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Suppress... by Fei-lin Ge (11611192)

“…LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

DataSheet3_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

DataSheet4_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

DataSheet1_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

DataSheet6_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”