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    Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner by Khondoker Alam (1443499)

    Published 2017
    “…Compared with vehicle control treatment, bortezomib pretreatment significantly decreased the maximal transport velocity (V<sub>max</sub>) of OATP1B3-mediated transport of CCK-8 (92.25 ± 14.2 vs. 133.95 ± 15.5 pmol/mg protein/min) without affecting the affinity constant (K<sub>m</sub>) values. …”