Abnormal Nuclear Morphologies. by Elisa Coluzzi (651262)

“…We observed a significant increase of NPBs 48 hrs after treatment and a decrease at subsequent times. …”

Lack of tau prevents impaired adult hippocampal progenitor cell proliferation in AICD-Tg mice. by Kaushik Ghosal (244754)

“…Compared to wild-type (left) there is a significant decrease in the number of DCX+ cells in the SGZ of AICD-Tg mice (right). …”

Figure S1 - The Mu Opioid Receptor Promotes Opioid and Growth Factor-Induced Proliferation, Migration and Epithelial Mesenchymal Transition (EMT) in Human Lung Cancer by Frances E. Lennon (541593)

“…<p><b>The MOR antagonist, naltrexone, inhibits epithelial mesenchymal transition (EMT) in human lung cancer cells.</b> <b>Panel A</b>: H358 human NSCLC cells were either untreated, treated with 100 nM morphine, DAMGO, fentanyl or 100 ng/ml EGF for 96 hours with or without pretreatment of cells with the MOR antagonist, naltrexone (100 nM). …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…CHF6297 administered intratracheally to rats dose-dependently counteracted the IL-1β (0.3 mg/kg)-induced neutrophil influx (ED₅₀ = 0.22 mg/kg) and increase in IL-6 levels (ED₅₀ = 0.82 mg/kg) in the BALF. …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…CHF6297 administered intratracheally to rats dose-dependently counteracted the IL-1β (0.3 mg/kg)-induced neutrophil influx (ED₅₀ = 0.22 mg/kg) and increase in IL-6 levels (ED₅₀ = 0.82 mg/kg) in the BALF. …”

Table 1_Synergistic effects of multi-enzyme supplementation on nutrient digestion and absorption in the foregut and hindgut.docx by Fangyuan Chen (2147119)

“…Additionally, 72 crossbred barrows [Duroc × (Landrace × Yorkshire)], weighing 25 kg, were fed one of six diets until their live weight approached 50 kg. The basal diets consisted of PC, NC1 and negative control 2 (NC2), while the remaining three diets were prepared by adding 100 mg/kg MCPC to the respective basal diets. …”

<i>Nlu-miR-34</i> is upregulated by JH through <i>Br-C</i>. by Xinhai Ye (6857771)

“…(E) Application of JH in LW-strain induced a strong bias towards development of SW BPHs (<i>p</i> = 0.003, n = 100). …”

Identification of the mitoBK_Ca channel in human astrocytoma mitochondria using the patch-clamp technique. by Piotr Bednarczyk (427876)

“…<p><b>A.</b> Schematic representation of the mitoplast preparation, patching of the mitoplast, and, finally, the patch-clamp experiment in the inside-out mode by means of the perfusion system. …”

DataSheet1_The Non-Steroidal Mineralocorticoid Receptor Antagonist KBP-5074 Limits Albuminuria and has Improved Therapeutic Index Compared With Eplerenone in a Rat Model With Miner... by Frédéric Jaisser (4885231)

“…KBP-5074 prevented the increase in UACR at 0.5, 1.5, and 5 mg/kg BID while eplerenone did so only at the two highest doses of 50 and 450 mg/kg BID. …”

Model simulations of feedback induced shift of Ca-current in wild-type and mutant zebrafish. by Lauw J. Klaassen (213346)

“…The value of was varied from 100% (A) to 10% (C) of the wild-type value <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001107#pbio.1001107-Fahrenfort1" target="_blank">[6]</a>. …”

Activation of AMPK prevented drugs-induced mitochondrial dysfunction. by Sun Woo Sophie Kang (3280878)

“…Percentages relative to respective controls were calculated. (<b>A</b>) AICAR prevented the decrease in cellular ATP in rat hepatocytes treated with acetaminophen (10mM, 24h) or diclofenac (250μM, 24h). …”

Stochastic presentation of tumor resistance to apoptosis induction. by Megan Olsen (248910)

“…<p>The rescue protocols are robust, as summarized from 665 random sampled experiments. (a) A system where cancer cells ignore up to 68% of signals still results in 100% success. …”

Imaging of Tryptophan Uptake and Exchange with FLIPW-CTYT in Human Oral Carcinoma KB Cells by Thijs Kaper (34812)

“…<p>(A) Perfusion of KB cells with various concentrations l-tryptophan (L-Trp) and 100 μM l-histidine (L-His) in Tyrode's buffer. …”

Supplementary Material for: Evaluation of Antidepressant-Like Activity of Novel Water-Soluble Curcumin Formulations and St. John's Wort in Behavioral Paradigms of Despair by Kulkarni S.K. (4131091)

“…<i>Results:</i> Three water-soluble curcumin formulations, C-5, C-20 and C-50 (50-200 mg/kg p.o.) decreased the immobility period, and increased serotonin and dopamine levels in the brain tissues. …”

Supplementary figure 1 by Cass Dedert (12837572)

“…</strong>Primary cortical neurons were incubated in Neurobasal medium containing either 25 mM (control), 50 mM, or 100 mM glucose. After 72 hours of treatment, viability showed a dose-dependent decrease as glucose concentration increased. …”

Disability worsening over two years according to domains of disability, for subjects with knee arthroplasty identified in 1999 (134 subjects) compared to the other participants (11... by Agnes Dechartres (84995)

“…</p>*<p>Worsening walking-distance limitation was defined by the decrease of a class (i.e., <100, 100–300, 300–500, 500–1000) to another.…”

Histopathology of skin and lung from control, tamoxifen-injected untreated and tamoxifen-injected Bosutinib-treated TBRI^ca-Col1a2-Cre transgenic mice. by Peter J. Wermuth (197533)

“…Skin sections from animals treated by subdermal osmotic pumps releasing 2.5 mg/kg/day, 5.0 mg/kg/day or 10 mg/kg/day of Bosutinib (<b>left panels</b>) display dose-dependent decreases in collagen deposition and dermal thickness compared with untreated mice. …”

Image_3_IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model.TIF by Mona Sohrabi (9082586)

Supplementary file 1_Pharmacokinetic and pharmacodynamic analyses of nafamostat in ECMO patients: comparing central vein and ECMO machine samples.pdf by Dong Hwan Lee (9908916)

“…NM was shown to inhibit the decrease in aPTT in the turnover model. In the patient model, the maximum inhibitory effect (Imax) of NM on the reduction of aPTT was 35.5%, and the concentration of NM required to achieve half of this maximum effect (IC50) was 350 μg/L. …”

Image_1_IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model.TIF by Mona Sohrabi (9082586)