Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

Subjects:

JHMV N1347A has decreased replication in the olfactory bulbs of mice. by Catherine M. Kerr (21492574)

Rhox5 decreases UNC5C expression. by Mayumi Sugimoto (151133)

Inhibition of PKC or Rho protein kinase decreases Ad5 wild type replication <i>in vitro</i>. by Alice Liu (4814415)

Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain. by Caio Maximino (100467)

“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”

Suppression does not depend on a growth rate decrease. by Laurent Jannière (28755)

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The receptors were activated by EC₅₀ concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

Scotopic and photopic light responses are decreased in WT and miR-150^-/- mice fed with HFD. by Liheng Shi (144105)

Loss of <i>SLC4A11</i> expression in hCEnC leads to decreased cell barrier function. by Doug D. Chung (3611387)

Loss of PAI-1-Vn interaction decreases proinflammatory cytokine and chemokine production after LPS challenge. by Kamlesh K. Gupta (709392)

Conditional depletion of RPS0A significantly decreases translation initiation rates. by Tomáš Kouba (153719)

Fibγ^Δ5 mice display decreased survival following <i>S. aureus</i> peritonitis. by Oscar Negrón (11965511)

Loss of Rtr1 activity leads to decreased RNAPII occupancy at <i>SNR</i> genes and shortened <i>SNR</i> transcripts. by Jose F. Victorino (8595885)

CD148 knockdown reduces cell-cell adhesion and E-cadherin contacts accompanied by a decrease in Rac1 activity in A431 cells. by Keiko Takahashi (375228)

“…CD148 knockdown reduces the E-cadherin contact formation accompanied by a decrease in Rac1 activity.</p>…”

Decreased thrombin activity levels in PAR KO following 24 hours following ischemia. by Efrat Shavit-Stein (3186678)

“…<p>(A) Total thrombin activity is significantly decreased in PAR1 KO compared to WT mice (t-test). …”

Decreased proliferation after overexpression of T-STAR in five breast cancer cell lines. by Sandra Sernbo (438551)

Acute myocardial infarction changes bone marrow cell composition and decreases endothelial differentiation capability. by Ming-Yao Chang (700415)

“…<p><b>(A)</b> CD14 positive cells increased at day 1 post-MI while the CD16 positive cell decreased at day 4 and day 7 after infarction in <b>B</b> with n ≥3 per groups. …”

STAT6-driven immunity decreases <i>N</i>. <i>brasiliensis</i> reproductive output and survival within host. by Annabel A. Ferguson (17616286)

Nrf2 activation decreases PMN ROS production in response to zymosan. by Doumet Georges Helou (7255823)

U87MG glioma cells transduced with gal-3 shRNA demonstrate decreased tumor size and growth. by Rafael Yamashita Ikemori (698128)

“…The inoculation of U87MG gal-3 shRNA cells in the flank of nuce mice (n = 5) demonstrated a decrease in tumor size and growth compared to the U87MG scramble shRNA (n = 6). …”