Changes in mean serum creatine kinase (CK) levels with age. by UnKyu Yun (11177542)

Expression and protein level of the extracellular calcium-sensing receptor (CaSR) were decreased in the hypertension groups. by Yuan-yuan Qu (446755)

Anti-CXCR3 group decreased number of specific CD8⁺ T cells as well as polyfunctionality after infection with <i>T</i>. <i>cruzi</i>. by Camila Pontes Ferreira (6194006)

Local injection of p29 alleviates the reduction in myofiber size by restoration of the decreased numbers of satellite cells. by Yutaka Ohsawa (587120)

Tg2576 mice treated with OG showed markedly increased α-secretase cleavage of APP and significantly decreased levels of Aβ generation. by She-Qing Zhang (446556)

Decreasing Hepatitis C Virus Infection in Thailand in the Past Decade: Evidence from the 2014 National Survey by Rujipat Wasitthankasem (732723)

Lumen diameter (77.9±5.6 vs 120.6±5.5 µm at 75 mmHg, <i>p</i><0.001), external diameter (110.4±6.4 vs 153.1±5.2 µm at 75 mmHg, <i>p</i><0.001) and media cross-sectional area (4860.4±464.7 vs 6972.4±272.1 µm² at 75 mmHg, <i>p</i><0.001) were increased in 16 wk-old db/db MRAs while wall:lumen ratio (21.3±1.2 vs 13.7±0.8 at 75 mmHg, <i>p</i><0.01) was decreased when compared to Db/db mice under physiological pressures of 50, 75 and 100 mmHg: a.... by Flavia M. Souza-Smith (346803)

120-kDa Notch1 transmembrane domain (N1™) is decreased in Pn−/− molar PDL. by Hideyuki Tanabe (243557)

miR-275 and miR-305 maternal loss-of-function mutants exhibited impaired flight capability, decreased hatching rate and survival rate. by Junfei Xie (3148638)

<i>PGRP-LC</i> knockdown in gut mitigates the decrease in lifespan caused by heat-killed <i>A</i>. <i>persici</i>. by Taro Onuma (15195377)

Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1. by Rajesh Jayachandran (542641)

“…Strong cortico-LA LTP was induced in wild-type [WT (grey symbols), <i>n</i> = 12, <i>p</i><0.05 versus baseline, <i>p</i><0.05 versus Cor 1 −/− (red symbols), Student's <i>t</i> test), but not in coronin 1–deficient mice [Cor 1 −/− (red), <i>n</i> = 7, <i>p</i>>0.05 versus baseline, Student's <i>t</i> test]. Scale bars, 50 pA and 20 ms. (G) Synaptic transmission and PPR in wild-type (left) and coronin 1–deficient mice (right) in the presence of forskolin. …”

Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation. by David W. Donley (3111198)

“…<p>Mouse pups were supplemented with carbonyl iron from postnatal days 10–17 and then were sacrificed at 14 weeks of age. <b>A.</b> Striatal IDO activity is increased in N171-82Q HD mice and significantly decreased by <i>ex vivo</i> iron (III) chelation (50 μM deferoxamine). …”

Down-regulation of NNMT expression decreased the plate efficiency and attenuated the capacity of colony formation in soft ager by Jun Zhang (48506)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)

a-f. PSP significantly decreased NP-specific IgM responses at days 4 and 21 compared to ACACIA. by Bhagwant Kaur Sekhon (847697)

An Analysis of Porphyrin Molecular FlexibilityUse of Porphyrin Diacids by Beisong Cheng (2970567)

“…Molecular mechanics calculations, using a modified version of MM2(87) and a newly developed force field for porphyrin diacids, correctly predict that the flexibility of <i>meso</i>-tetraaryl porphyrin diacids decreases as the steric bulk of the peripheral substituents increases:  [H₄TPyP]²⁺ ≈ [H₄TPP]²⁺ > [H₄T-2,6-(OH)₂ PP]²⁺ ≈ [H₄T-2,6-F₂ PP]²⁺ > [H₄T-2,6-Cl₂ PP]²⁺ ≈ [H₄TMP]²⁺. …”

Figure S1 - Docosahexaenoic Acid Decreases Pro-Inflammatory Mediators in an <i>In Vitro</i> Murine Adipocyte Macrophage Co-Culture Model by Anna A. De Boer (510740)

Former Abusers of Anabolic Androgenic Steroids Exhibit Decreased Testosterone Levels and Hypogonadal Symptoms Years after Cessation: A Case-Control Study by Jon Jarløv Rasmussen (2993427)

“…</p><p>Methods</p><p>This study had a cross-sectional case-control design and involved 37 current AAS abusers, 33 former AAS abusers (mean (95%CI) elapsed duration since AAS cessation: 2.5 (1.7; 3.7) years) and 30 healthy control participants. …”

Annual treatment frequencies in all eyes. by Yasuyuki Sotani (20114144)

“…Outpatient visit frequency also significantly declined from 11.5 ± 4.3 visits in the year before surgery to 8.8 ± 4.1, 5.0 ± 3.4, and 4.4 ± 3.2 visits in the first, second, and third postoperative years, respectively (Kruskal-Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g004" target="_blank">Fig 4</a>).…”

Annual number of outpatient visits in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…<p>In the recurrence group, mean outpatient visits (± standard deviation) decreased from 13.6 ± 3.0 to 11.9 ± 5.0, 8.1 ± 3.9, and 7.8 ± 3.2 at 1, 2, and 3 years postoperatively, respectively (Kruskal-Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”