Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor by Thérèse Keravis (188522)

“…NCS 613 is a potent inhibitor, which is more selective for the PDE4C subtype (IC₅₀ = 1.4 nM) than the other subtypes (PDE4A, IC₅₀ = 44 nM; PDE4B, IC₅₀ = 48 nM; and PDE4D, IC₅₀ = 14 nM). …”

Comparison of CYP26A1, CYP26B1 and LRAT expression in normal colonic mucosa, primary colorectal cancer and lymph node metastasis. by Gordon T. Brown (532127)

Three dimensional evaluation of the skeletal and temporomandibular joint changes following stabilization splint therapy in patients with temporomandibular joint disorders and mandi... by Ahmed, Madiha Mohammed Saleh

“…Methods: This study is a retrospective clinical study that enrolled 26 adult patients with TMD and MD with a mean age of 24.86 years. …”
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Brain-specific deletion of <i>Mef2a</i> and <i>Mef2d</i> causes impairments in motor coordination, as well as presynaptic release probability. by M. Waseem Akhtar (326982)

“…(<b>H</b>) Paired-pulse facilitation is increased in <i>Mef2a/d</i>^DKO mice at Inter-Stimulus Interval 20, 30, 50, 100, 200 and 400 (mS) compared to littermate CTLs, suggesting decreased presynaptic release probability (CTL, n=8; <i>Mef2a/d</i>^DKO, n=7). …”

Analysis of targeted MLX deletion in Sertoli cells. by Patrick A. Carroll (11586792)

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx by Chao Zhou (471522)

“…Nonetheless, how organic manure substitution regulates microbial communities to influence soil quality and crop yield remains unclear. </p>Methods<p>A one-year field experiment comprising four organic manure substitution rates (25%, 50%, 75%, and 100%) along with a no-substitution control was conducted. …”

Fig 3 - by Joseph Musaazi (834535)

Supplementary file 1_Effect of Bifidobacterium longum subsp. infantis YLGB-1496 on common diseases in pediatrics: a randomized, blinded, placebo-controlled trial.docx by Xi Zhang (83736)

“…</p>Methods<p>Eligible healthy children were randomly assigned to either an intervention group (IG, n = 50), which received the probiotic, or a control group (CG, n = 50), which received a placebo, for a duration of 3 months. …”

Summary of mid/peri-pubertal EtOH exposure on miRNA and mRNA gene expression. by Sarah A. Prins (507483)

Data_Sheet_1_The Association Between Alveolar Dead Space Fraction and Mortality in Pediatric Acute Respiratory Distress Syndrome: A Prospective Cohort Study.docx by Sheow Boon Oh (12157812)

“…This study aims to characterize AVDSF in patients with pediatric ARDS (PARDS), to determine its association with clinical outcomes and examine the validity of a previously studied cutoff (AVDSF > 0.25).</p>Methods<p>This was a prospective cohort study performed in the setting of a lung protective mechanical ventilation protocol. …”

The method presented in this paper for quickly identifying a network’s MIB using spectral clustering makes it possible to quickly measure integrated information in large brain netw... by Daniel Toker (6311834)

“…The green line passes through the mean across networks. <b>C</b> Increasing <i>p</i> also systematically <i>decreased</i> the modularity <i>Q</i> of the networks. …”

Table_2_Impact of traditional Chinese Baduanjin exercise on menstrual health among international female students studying in China: a randomized controlled trial.DOC by Asem Alkhatib (11244708)

“…In addition, the results of the MANOVA indicated statistically significant decreases in scores for the two subscales of MSQ: premenstrual symptoms (intervention: 17.07 ± 3.33 vs. control: 28.42 ± 7.56; F = 44.70, P < 0.01)and menstrual pain (16.03 ± 4.53 vs. 19.58 ± 5.14; F = 6.50, P < 0.05). …”

Table_1_Impact of traditional Chinese Baduanjin exercise on menstrual health among international female students studying in China: a randomized controlled trial.DOC by Asem Alkhatib (11244708)

“…In addition, the results of the MANOVA indicated statistically significant decreases in scores for the two subscales of MSQ: premenstrual symptoms (intervention: 17.07 ± 3.33 vs. control: 28.42 ± 7.56; F = 44.70, P < 0.01)and menstrual pain (16.03 ± 4.53 vs. 19.58 ± 5.14; F = 6.50, P < 0.05). …”

Synaptic plasticity and coincidence detection in the model Kenyon cell. by Luca A. Finelli (44577)

“…<p>(A) The SRDP rule was applied every 100 ms (large box over dashed time grid, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000062#s4" target="_blank">Materials and Methods</a>). …”

Increase in spike phase locking in animals trained in the visuospatial task. by Isabel A. Muzzio (262507)

“…The STA for the animal in the visuospatial group has a clear oscillatory component with a periodicity of about 20 ms (50 Hz). …”

Changes in disease burden in Poland between 1990–2017 in comparison with other Central European countries: A systematic analysis for the Global Burden of Disease Study 2017 by Maria Gańczak (8519883)

“…For both YLLs and YLDs, greater relative declines were observed for females. There was a large decrease in communicable, maternal, neonatal, and nutritional disease DALYs (48.2%; 46.3–50.4). …”

M002 treatment of neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…In the SK-N-AS xenografts <b>A</b>, there was a significant decrease in tumor growth beginning at day 7 that continued to the end of the study. …”

Z-stack through a mouse kidney in vivo, showing typical renal structures like glomeruli (g), proximal tubules (pt) and extraglomerular capillaries (arrows). by Ina Maria Schießl (288061)

“…Without an adjustment of laser power, resolution decreased rapidly so that tissue in a depth of 50 µm was barely accessible. b, right column: Z-stack with adjusted laser power. …”

<i>Ssdp</i> pan-neuronal knockdown affects adult brain development. by Safa Salim (9186786)

“…Each black dot is a data point representing an independent biological replicate with 20 individual fly heads per biological replicate. …”

<i>Ssdp</i> overexpression causes abnormalities in mitochondrial morphology and dynamics. by Safa Salim (9186786)

“…Horizontal red line represents the mean value. Each black dot is a data point representing an independent biological replicate. …”