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ms decrease » a decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
ht decrease » a decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
_ decrease » _ decreased (Expand Search)
e decrease » a decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
_ e » _ em (Expand Search)
ms decrease » a decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
ht decrease » a decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
_ decrease » _ decreased (Expand Search)
e decrease » a decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
_ e » _ em (Expand Search)
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Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain.
Published 2014“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”
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U87MG glioma cells transduced with gal-3 shRNA demonstrate decreased tumor size and growth.
Published 2014“…The delay presented for the decrease in tumor size and growth in the gal-3 shRNA cells was not due to a decreased tumor cell proliferation <i>in vitro</i> when compared to scramble shRNA cells. …”
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Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction.
Published 2019“…<p>(A–F) the neural activity of the RID changes during the transition periods from backward to forward locomotion (A–C) and from forward to backward locomotion (D–F) in the mock (A: p = 1.5 × 10<sup>−5</sup>; D: p = 5.5 × 10<sup>−13</sup>), 5-HT exposed (B: p = 0.092; E: p = 0.79), and <i>mod-1</i> mutant (C: p = 0.081; F: p = 0.93) groups. …”
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Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1.
Published 2014“…Strong cortico-LA LTP was induced in wild-type [WT (grey symbols), <i>n</i> = 12, <i>p</i><0.05 versus baseline, <i>p</i><0.05 versus Cor 1 −/− (red symbols), Student's <i>t</i> test), but not in coronin 1–deficient mice [Cor 1 −/− (red), <i>n</i> = 7, <i>p</i>>0.05 versus baseline, Student's <i>t</i> test]. Scale bars, 50 pA and 20 ms. (G) Synaptic transmission and PPR in wild-type (left) and coronin 1–deficient mice (right) in the presence of forskolin. …”
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