Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …"
احصل على النص الكامل

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …"
احصل على النص الكامل
احصل على النص الكامل

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
احصل على النص الكامل
احصل على النص الكامل

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Al-Amleh, Esraa K.

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
احصل على النص الكامل
احصل على النص الكامل

MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. …"
احصل على النص الكامل
احصل على النص الكامل

Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant حسب Abdal-hay, Abdalla

"…The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. …"
احصل على النص الكامل
احصل على النص الكامل

The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons حسب Zupin, Luisa

"…In this study, a possible molecular mechanism of the 905 nm PBMT (0.25 W/cm2; 3, 6, 12, and 18 J/cm2, 5 Hz) analgesic effect was tested on 50B11 cells, by investigating its impact on mitochondria. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Linear hydrogen gas sensors based on bimetallic nanoclusters حسب Ayesh, Ahmad I.

"…The sensors were found to be sensitive at low concentrations of hydrogen at room temperature, and exhibit a linear relationship between hydrogen concentration and the sensitivity. …"
احصل على النص الكامل
احصل على النص الكامل

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

احصل على النص الكامل
احصل على النص الكامل

Event-triggered fault detection for discrete-time linear systems حسب Hajshirmohamadi, S.

"…In this paper the problem of event-triggered fault detection filter for discrete-time linear systems is considered and a multi-objective formulation of the problem is presented based on H, H- and generalized H2 performance criteria. …"
احصل على النص الكامل
احصل على النص الكامل

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

"…Moreover, NSP-B suppressed FOXM1-regulated genes, such as Aurora Kinases A and B, CDKs 4 and 6, and PLK1. …"
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

"…Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …"
احصل على النص الكامل
احصل على النص الكامل

Event-Triggered fault detection, isolation and control design of linear systems حسب Davoodi, M.R.

"…It is shown that by using an event-Triggered technique applied to both the sensor and filter nodes, the amount of data that is sent through the sensor-To-filter and filter-To-Actuator channels are dramatically decreased. A set of linear matrix inequality (LMI) feasibility conditions are derived to ensure the solvability of the problem as well as to simultaneously obtain the filter parameters and the event-Triggered conditions. …"
احصل على النص الكامل
احصل على النص الكامل

Event-triggered fault detection and isolation for discrete-time linear systems حسب Hajshirmohamadi, Shahram

"…In this study, the problem of event-triggered fault detection and isolation (FDI) for discrete-time linear time invariant systems is considered. Using a Leunberger observer as the residual generator, a multi-objective formulation of the FDI problem is presented based on l1, H- and H? …"
احصل على النص الكامل
احصل على النص الكامل

Linear dynamics modelling of droplet deformation in a pulsatile electric field حسب Vivacqua, Vincenzino

"…A linear dynamic model of water droplet deformation in the presence of an electric field has been developed. …"
احصل على النص الكامل
احصل على النص الكامل

Multicarrier Microgrid Operation Model Using Stochastic Mixed Integer Linear Programming حسب Mehrjerdi, Hasan

"…The model is expressed as a stochastic mixed integer linear programming problem. Both active and reactive powers are modeled. …"
احصل على النص الكامل
احصل على النص الكامل

Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances حسب Hossain, Ajad

"…Non-Linear loads such as Compact Fluorescent lamps (CFLs), Light Emitting diodes (LEDs),Solid state voltage regulators, and variable speed electric drives are increasingly being added tothe domestic, residential and industrial power network. …"
احصل على النص الكامل
احصل على النص الكامل

Event-triggered fault detection for discrete-time linear multi-agent systems حسب Hajshirmohamadi, S.

"…/H- performance index is guaranteed and it is shown that by using an event-triggered technique, the amount of data that is sent by each agent to its neighboring agents is dramatically decreased. Sufficient conditions for the solvability of the problem are obtained in terms of linear matrix inequalities (LMIs) where extended LMI characterizations are used to reduce the conservativeness of the multi-objective H?…"
احصل على النص الكامل
احصل على النص الكامل