يعرض 41 - 60 نتائج من 1,124 نتيجة بحث عن '(( 50 ((ms decrease) OR (a decrease)) ) OR ((( 1 b decrease ) OR ( a we decrease ))))*', وقت الاستعلام: 0.22s تنقيح النتائج
  1. 41
  2. 42

    Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. حسب Padmanabhan, Regina

    منشور في 2022
    "…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …"
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  3. 43

    A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies حسب Mohamed Bakr, Hussain

    منشور في 2020
    "…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …"
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  4. 44
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    Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey حسب Turner, Stuart J.

    منشور في 2013
    "…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. …"
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  6. 46
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    Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride حسب Radwan A.B.

    منشور في 2019
    "…Using only a 50 ?mol L?1 of BTC, we are able to measure an inhibition efficiency of 91, 79, and 71% in SCP solution with 3.5% NaCl at pH of 12.5, 10 and 7, respectively without showing any effect on the mechanical properties on the cured mortars. …"
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  8. 48

    Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Alhujaily, Muhanad

    منشور في 2021
    "…Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. …"
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  9. 49

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

    منشور في 2017
    "…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …"
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  10. 50

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

    منشور في 2017
    "…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …"
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    article
  11. 51

    The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells. حسب Attafi, Ibraheem M

    منشور في 2019
    "…The toxic effects of Pb on the lung was associated with significant increases in NF-κB and AhR levels which was accompanied with increases in downstream targets genes, iNOS and CYP1A1, respectively. …"
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  12. 52

    Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby حسب Mohamed, Islam

    منشور في 2020
    "…Thus, EA extract causes a dramatic decrease in cell motility and invasion abilities of FaDu and SCC25 cancer cells in comparison with their controls. …"
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  13. 53

    Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

    منشور في 2022
    "…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …"
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  14. 54

    The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes حسب Posa, Aniko

    منشور في 2017
    "…After 24 h of the administrations, inflammatory mediators such as interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-) and myeloperoxidase (MPO) enzyme as well as heme oxygenase (HO) activity were measured in both plasma and cardiac tissue, along with serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …"
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  15. 55

    Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts. حسب Ardah, Mustafa T

    منشور في 2020
    "…In order to investigate the inhibitory mechanisms of these two compounds towards fibril formation, we demonstrated that salvianolic acid B binds predominantly to monomers, while dihydromyricetin binds to oligomeric species and to a lower extent to monomers. …"
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  16. 56

    Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO2 with Exceptional Textural Properties and Superior Adsorption Kinetics حسب Ahmad, Yahia H.

    منشور في 2022
    "…The average particle size ranged between 9.7 and 27.5 nm and it decreased with increasing the Mo content. Furthermore, Mo-TiO2 revealed mesoporous architectures with a high surface area ranging between 170 and 260 m2 g−1, which is superior compared to previously reported Mo-doped TiO2. …"
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  17. 57

    A Multi-echelon Network Distribution Model For Emergency Resource Planning حسب Pradhananga, Rojee

    منشور في 2014
    "…In this research, we develop a novel multi-echelon network distribution structure for emergency resource planning. …"
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  18. 58

    Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) حسب Saragusty, Joseph

    منشور في 2014
    "…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …"
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  19. 59

    A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway حسب Berry, Thomas

    منشور في 2019
    "…There is a decrease in aconitase 1 (ACO1) in AD. ACO1 is an iron-sulfur enzyme in the citric acid cycle that upon loss of an iron-sulfur cluster converts to iron regulatory protein 1 (IRP1). …"
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  20. 60