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ms decrease » _ decrease (Expand Search)
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…Our predictions revealed that E17K, R67W, V164G, E319G, R391G, D32Y, L52H, L52R, and W80R were the most pathogenic mutations. …”
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Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
Published 2016“…Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
Published 2020“…The negatively-charged side chains of two aspartate residues (D179 and D180) within the β8-β9 loop are crucial for the N-terminal inter-subunit interaction. …”
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…Furthermore, the overexpression of active NHE1 elicited modulation of gene expression in cardiomyocytes including an upregulation of myocardial osteopontin (OPN) expression. …”
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The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
Published 2023“…Furthermore, data indicated a decrease in sarcosine synthesis from glycine and choline and increase in spermidine synthesis in the BCG vaccinated cohort in T2D and non-T2D groups, respectively. …”
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Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
Published 2020“…The combination of cisplatin and BI-D1870 also resulted in the inhibition of LC3 II to LC3 I expression when compared to BI-D1870. …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression. …”
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Biochar of spent coffee grounds as per se and impregnated with tio2: Promising waste-derived adsorbents for balofloxacin
Published 2021“…Surface morphology, functional moieties, and thermal stabilities of both adsorbents were scrutinized using SEM, EDS, TEM, BET, FTIR, Raman, and TG/dT analyses. BET analysis indicated that the impregnation with TiO2 has increased the surface area (50.54 m2 /g) and decreased the pore size and volume. …”
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Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H2S: DFT study
Published 2021“…Moreover, the adsorption distance (D) between H2S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…However, implementing interventions to decrease the T2D incidence, lower SBP, reduce the number of smokers, and improve the total cholesterol could yield gains of 200,408, 198,173, 194,725, and 113,462 PALYs, respectively. …”
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Improving Concrete Durability by Using Optimized Aggregate Gradation and Reducing Cement Content
Published 2020“…The main findings from this study are as follows: (1) The cementitious content of typical Florida pavement and structural concrete can be reduced by as much as 10 to 15% without loss in workability of the fresh concrete, and without decreasing the strength and durability of the hardened concrete. (2) Portlandlimestone cement (Type IL) can be used as a substitute for ordinary Portland cement (Type I/II). (3) The OAG technique can be used to efficiently reduce the cementitious content of the concrete mixes and to improve their performance."…”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions
Published 2013“…The overall rate law is represented by Eq. (2) where [CuIL]t and K 1 represent the total copper(II) complex concentration and the pre- equilibrium formation constant, respectively. d [CuL+]/dt = {(ko+k₁ [H+]) [SBr] [CuL]}/(1 + K₁ [SBr])…”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
Published 2020“…Induction of apoptosis by VCX treatment induced cell cycle arrest at G0/G1 phase with inhibition of cell proliferator genes, cyclin D1 and E2F1. …”
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