Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Reinforcement of polyacrylamide-co-tert-butyl acrylate base gel using nanosilica for conformance control at low and high reservoir temperatures by Shamlooh M.

“…Therefore, this study introduces a new polymeric formulation that serves as a water shut-off agent for reservoirs at low and high temperatures. …”
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Anaerobic and aerobic contributions to repeated supramaximal cycling exercises and their adaptation to high-intensity interval training in obese perimenopausal and postmenopausal w... by Jabbour, Georges

“…Results The results showed that, before training, the anaerobic contributions to repeated SCE did not differ between the perimenopausal and postmenopausal women for the first three repetitions. However, a higher decrease was reported for postmenopausal women at the fourth and fifth repetitions (P < 0.01, respectively). …”
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A Prospective Association of Nut Consumption with Cognitive Function in Chinese Adults aged 55+ _ China Health and Nutrition Survey. by Li, M

“…Nut consumption was collected using 3-day 24 recall method in 1991, 1993, and at surveys of cognition assessment. …”
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Yerba Maté (Illex Paraguariensis) ingestion augments fat oxidation and energy expenditure during exercise at various submaximal intensities by Alkhatib, Ahmad

“…These changes were combined with a trend towards a decrease in BLC (P = 0.066), and without a significant difference inV˙O2peak, peak power, peak RER, or peak BLC. …”
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Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties by Mohammed, Alsafran

“…In contrast, alkali-treated fibers showed a significant decrease in radical scavenging activity (almost 7–8 fold) and reducing power potential (6-fold) and exhibited no antifungal activity, potentially due to the loss of bioactive components such as lignin and essential oils. …”
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Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants by El-Basiony, Nasser M.

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Reducing the number of rebooking of urgent in-person visits in general paediatric ambulatory clinics during the COVID-19 pandemic by Hassan, Manasik

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مستوى الحكم التأملي للمعرفة العلمية وآليات تبريرها لدى معلمي العلوم ذوي الخبرة بسلطنة عمان by الحجرية, فاطمة بنت حمدان

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Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures by ALANI, AYA AHMED

“…Due to the rapid growth of facial bone in the pediatric age group, the use of metallic plates would require a second surgical intervention to remove it. The alternative is biodegradable plating systems which are safe but not without complications, including learning curve, decreased stability, cost, and infection. …”
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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region by Dagenais, Renée

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Uv-l/sulfite advanced reduction process as an efficient method for chlorate reduction in water by Bensalah, Nasr

“…However, the presence of Fe3+ enhanced chlorate reduction yield due to the formation of additional SO3 •– radicals from the photodecomposition of Fe(III)-HSO3 – complexes. …”
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Age-Related Differences of the Athlete`s Heart by Kneffel, Zsuzsanna

“…LV hypertrophy is less marked or missing at the older ages (50-80 years). Left ventricle muscle mass (LVMM) is higher in older endurance athletes than in age-matched non-athletes (5) but the difference between athletic and non-athletic subjects decrease continuously or disappears during the ageing. …”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis by Smatti, Maria K.

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations. …”
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The effect of triiodothyronine on maturation and differentiation of oligodendrocyte progenitor cells during remyelination following induced demyelination in male albino rat by El-Tahry, H.

“…After three weeks, significant improvement in myelination was detected in T3-treated group compared to +ve control as detected by both MBP immunohistochemistry and electron microscopy. After one week of cuprizone withdrawal, PDGFRα positive cells and gene expression showed significant increase in +ve control and T3-treated groups as compared to −ve control with insignificant difference in between the former two groups. …”
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Greater effects of high- compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese ado... by Racil, G.

“…Forty-seven participants were randomly assigned to one of three groups receiving either a 1:1 ratio of 15 s of effort comprising moderate-intensity interval training (MIIT at 80% maximal aerobic speed: MAS) or high-intensity interval training (HIIT at 100% MAS), with matched 15 s recovery at 50% MAS, thrice weekly, or a no-training control group. …”
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Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells by Zupin, L.

“…It was previously shown, in in vitro models of infections, that the LED blue light is able to decrease the viral load of HSV-1 and ZIKV. In our study, LED photobiomodulation therapy (PBMT) at blue wavelengths (450, 454 and 470 nm) was tested in an in vitro model of SARS-CoV-2 infection, employing three experimental settings: SARS-CoV-2 was irradiated and then transferred to cells; already infected cells were irradiated; cells were irradiated prior to infection. …”
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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Results: Consumption of systemic antifungal agents increased from 0.50 (in 2008) to 0.92 defined daily dose (DDD)/1000 inhabitants/day (in 2018), with a compound annual growth rate of 6.2%. …”
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Effects of Combined Calcium Hypochlorite and Chlorine Dioxide on Drinking Water Quality in Qatar and Disinfection by Products Formation by Mohamed, Elsamoul H.

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Flight Scheduling in the Airspace by Msakni, Mohamed Kais

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