Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

“…M annonacin treated vs. 7% of cells in G1 phase in control group. In addition, a dose-dependent decrease in the phosphorylation of p70S6 kinase (a downstream target of mTOR) was observed with annonacin treatment at both 24 and 48 h end-points. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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Prevention of oral cancer by Malki, Ahmed Mohamed

“…Current research also focuses on emerging gene therapy through employing adenoviruses. This chapter will address and focus on the aforementioned prevention strategies, elaborating and expanding on risk factors and how to decrease chances of developing oral cancer. …”
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Comparison of performance and health indicators between perimenopausal and postmenopausal obese women: the effect of high-intensity interval training (HIIT). by Jabbour, Georges

“…Sixteen PERIM women (average age 49.6 y), 21 POSTM1 women (average age 50.6 y), and 19 POSTM2 women (average age 69.6 y) completed a 6-week HIIT intervention. …”
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Investigating the effect of polymer-modified graphene oxide coating on RO membrane fouling by Ashfaq, Mohammad Y.

“…The membrane surface characterization showed a decrease in membrane surface roughness from 74.7 nm to 69.0 nm and an increase in membrane hydrophilicity as the contact angle decreased from 41.7 ± 4.50 to 22.0 ± 1.10. …”
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Evaluation of the Effect of Moringa peregrina Extract on Learning and Memory: Role of Oxidative Stress by Alzoubi, Karem H.

“…In particular, an increase in glutathione (GSH), a decrease in oxidized glutathione (GSSG), and an increase in the antioxidant enzyme glutathione peroxidase (GPx) levels in the hippocampus were elicited after treatment with M. peregrina. …”
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Utilization of Emergency Services by Children with Asthma in Qatar by Arafah, Dima

“…Background: Asthma is a leading chronic disease in children worldwide, which if left untreated or poorly controlled, can lead to altered lung function and poor quality of life. 1 Early detection and improved control of asthma are recommended to decrease utilization of emergency services and hospitalizations. …”
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The expression of bile acid Receptor TGR5 in Adipose Tissue in Diet-induced obesity mice by Ahmed, Sumaya

“…There was significant downregulation of TGR5 gene expression level in obese (DIO) mice and remarkable upregulation of TGR5 gene expression after successful weight loss in DIO mice treated with SFN in time dependent manner at 1 weeks and 4 weeks of ip applications. …”
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Correlation between delta-endotoxin and proteolytic activities produced by Bacillus thuringiensis var. kurstaki growing in an economic production medium by Ennouri, Karim

“…Maximal protease activity (540-2468 UI) obtained by BUPM5-1 and BUPM5-2 was 2.34-fold and 10.7-fold, respectively, more than that obtained by the wild strain BUPM5 with a drastic decrease of their delta-endotoxin production. …”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells. by Alhoshani, Ali

“…Induction of apoptosis by VCX treatment induced cell cycle arrest at G0/G1 phase with inhibition of cell proliferator genes, cyclin D1 and E2F1. …”
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Unveiling into Genetic Architecture of Transgenerational Stress Memory via Promoting Drought Tolerance in Barley by Alqudah, Ahmad M.

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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…In addition, a significant up regulation in gene and protein expression profile of stage specific cell markers for OPCs/OLs (CNPase, Galc, NG2, MOG, OLIG1, OLIG2, MBP), neurons, and astrocytes (MAP2, β-TubulinIII, GFAP) and concomitant decrease of OBNSCs pluripotency markers (Oct4, Sox2, Nestin), was demonstrated following induction of OBNSCs differentiation. …”
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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

“…Increased MG induced by high glucose concentration activated IRE1α, PERK and ATF6 and related downstream signalling leading to increased chaperone, apoptotic and inflammatory gene expression. …”
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Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies by Furuya-Kanamori, Luis

“…Meta-analyses of diagnostic accuracy studies are a fundamental component of evidence-based medicine, and they are extensively used in medical imaging and the clinical laboratory. …”
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Effects of the P20 protein from Bacillus thuringiensis israelensis on insecticidal crystal protein Cry4Ba by Jaoua, Samir

“…To investigate its putative role in Cry4Ba delta-endotoxin production and toxicity, a p20 gene was cloned and introduced into B. thuringiensis recombinant strain expressing cry4Ba type gene (cry4BLB). …”
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Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures by ALANI, AYA AHMED

“…Due to the rapid growth of facial bone in the pediatric age group, the use of metallic plates would require a second surgical intervention to remove it. The alternative is biodegradable plating systems which are safe but not without complications, including learning curve, decreased stability, cost, and infection. …”
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Pilot-scale petroleum refinery wastewaters treatment systems: performance and microbial communities' analysis by Karray, Fatma

“…The reduction of the COD, BOD5, phenols, and the total petroleum hydrocarbon (TPH) reached 82.10%, 85.87%, 91.63%, and 81.11%, respectively at high hydraulic residence time (HRT = 10 days). Decreasing HRT to 5 and 2.5 days led to a decrease in the efficiency of the process and a decrease in biomass concentration was also observed (<1000 mg/l). …”
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Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart by Amara, Issa E.A.

“…Our results showed that mercury treatment caused a significant induction of the cardiac hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP); in addition to Cyp1a1, Cyp1b1, Cyp2b9, Cyp2b10, Cyp2b19, Cyp2c29, Cyp2c38, Cyp4a10, Cyp4a12, Cyp4a14, Cyp4f13, Cyp4f15, Cyp4f16 and Cyp4f18 gene expression. …”
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Effect Of The Apical Ectodermal Ridge On Mitotic Index In Hind Limb Bud Mesenchyme In Bufo Regularis by Abdel Karim, Ahmed E.

“…The operated bud (80% of cases) showed a decrease in its volume and there was no significant difference in mesenchyme MI. …”
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S‐Fertilizer (Elemental Sulfur) Improves the Phytoextraction of Cadmium through Solanum nigrum L. by Alatawi, Aishah

“…The application of Gyp 100 mg kg−1 boosted plant growth and physiology along with oxidants and antioxidants activity as compared to ES 100 mg kg−1 alone, and combine application of GYP+ES 50 + 50 mg kg−1. The application of ES 100 mg kg−1 showed an effective approach to decreasing Cd uptake as compared to Gyp 100 mg kg−1. …”
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