Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Jaimie D, Steinmetz

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STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJ... by El Gamal, Heba

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New genetic insights into improving barley cope with salt stress via regulating mineral accumulation, cellular ion homeostasis, and membrane trafficking by Samar G., Thabet

“…The genomic analysis lead to having in total, of 146 associated SNPs with salt-responsive traits using 19 K SNPs in a genome-wide association study analysis. High significant SNPs were located within or near candidate genes which are potentially involved in the stress tolerance mechanism via enhancing the expression of Na+/H+ antiporters and tonoplast H+-ATPase. …”
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Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes by Younes, Noura B.

“…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. …”
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Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex by Bat-Erdene, Jugder

“…Reduced expression of the histone acetyltransferase Tip60 decreased IMD signaling and blocked rescue by dietary acetate and other sources of intracellular acetyl-CoA. …”
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EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS by Saif, Atiya Ramadan

“…The expression of Adhesion proteins (ICAM-1 and E-selectin) were increased in hyperglycemia and decreased expression with PBA. Conclusion: Our results suggest that hyperglycemia may activate ER stress that could play a role in the angiogenesis in the diabetic retinopathy.…”
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An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD and Disulfiram. by J, Christy Priyadharshini

“…Alcohol use disorder (AUD) is a multifactorial psychiatric behavior disorder. …”
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Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma... by Salagre, D.

“…Compared to the control groups, melatonin decreased the body weight gain and visceral fat in ZDF rats of both sexes. …”
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Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging mice by Cugno, Chiara

“…, and pro-inflammatory cytokines, and a higher level of anti-inflammatory cytokines were observed. …”
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