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341
MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. Additionally, we did not we did not observe correlation between IRAK3 and MYD88 gene expression and TNF-α, IL-6, IL-2 and IL-10 levels. …”
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342
Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar
Published 2014“…HPV 81, 11 and 16, in decreasing order were the most commonly identified genotypes. …”
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343
Adrenoceptor Desensitization: Current Understanding of Mechanisms
Published 2024“…In this context, this review discusses the different patterns of desensitization of the α1-, α2- and the β adrenoceptors and highlights the role of β-arrestins in regulating physiologic responsiveness through desensitization and biased agonism. …”
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Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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346
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
Published 2024“…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …”
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Enhanced Filtration Characteristics and Reduced Bacterial Attachment for Reverse Osmosis Membranes Modified by a Facile Method
Published 2021“…The original membrane showed a water contact angle of ∼90−100° that was significantly decreased after silane coating: 63° for 3-APS and ∼52° for 6-AHAS. …”
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351
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
Published 2017“…We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …”
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352
Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …”
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353
Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …”
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354
Effect of binary mixture of waste plastics on the thermal behavior of pyrolysis process
Published 2015“…It was also found that secondary reaction occurred when mixing two types of plastics. The activation energy of the first step pyrolysis reaction is also higher than the secondary reaction. …”
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355
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
Published 2020“…BK altered the expression of 72 (4%) and 120 (6.5%) proteins, whereas leptin altered the expression of 189 (10.2%) and 127 (6.5%) proteins after 24 and 48 h, respectively, compared to control RASMC. …”
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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. Patients were followed for 6 weeks to trace early postoperative complications (infection, dehiscence, and necrosis) and the establishment of protective sensation (pain and temperature). …”
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358
A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
Published 2022“…In addition, the histological analysis of liver tissues proved significant injury and hepatocellular necrosis. WE and NE extract showed a relatively high in vitro radical scavenging (ORAC) and averting activities (HORAC) with a polyphenol content of 3.6 % and 2.9 %, respectively. …”
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359
Regional Difference in the Association between the Trajectory of Selenium Intake and Hypertension: A 20-Year Cohort Study.
Published 2021“…The effect of selenium on hypertension is inconclusive. We aimed to study the relationship between selenium intake and incident hypertension. …”
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360
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…Globally, the HF age-standardised prevalence and YLDs decreased by 7.06% (95% UI: −7.22%, −6.9%) and 6.82% (95% UI: −6.98%, −6.66%) respectively, from 1990 to 2019. …”
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