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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…Marked at time = 0 is the onset of the 100-ms white noise. (f) A second group of mice followed the same procedures but without experiencing daily restraint stress (<i>N</i> = 3 mice, <i>n</i> = 123 neurons). …”
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Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1.
Published 2014“…Strong cortico-LA LTP was induced in wild-type [WT (grey symbols), <i>n</i> = 12, <i>p</i><0.05 versus baseline, <i>p</i><0.05 versus Cor 1 −/− (red symbols), Student's <i>t</i> test), but not in coronin 1–deficient mice [Cor 1 −/− (red), <i>n</i> = 7, <i>p</i>>0.05 versus baseline, Student's <i>t</i> test]. Scale bars, 50 pA and 20 ms. (G) Synaptic transmission and PPR in wild-type (left) and coronin 1–deficient mice (right) in the presence of forskolin. …”
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Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC.
Published 2025“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”
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SLE decreases risk for hormonal cancers.
Published 2021“…An OR to the left of the solid line represents a reduction in risk. (a) Breast cancer incidence in female SLE cohort is significantly decreased by SLE status (OR 0.52, 95% CI 0.35, 0.74, p = 0.0036). …”
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Acute myocardial infarction changes bone marrow cell composition and decreases endothelial differentiation capability.
Published 2015“…<p><b>(A)</b> CD14 positive cells increased at day 1 post-MI while the CD16 positive cell decreased at day 4 and day 7 after infarction in <b>B</b> with n ≥3 per groups. …”
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Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis
Published 2013“…Notably, miR-155, a known regulator of liver inflammation, had the highest fold increase in cirrhotic livers (2.2-fold, P=4.16E-08) and significantly correlated with hepatic CYP3A activity (r=-0.50, P=0.017). …”
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