Kylo-0603’s EC50 & tissue levels. by Xueqin lu (22250795)

Discovery of Novel Coumarin Pleuromutilin Derivatives as Potent Anti-MRSA Agents by Kai Liu (159026)

“…Compound <b>14b</b> displayed particularly rapid bactericidal effects, slow resistance development, and low cytotoxicity. Moreover, it decreased bacterial loads in the lung, liver, kidney, spleen, and heart and exhibited better antibacterial efficacy (ED₅₀ = 11.16 mg/kg) than tiamulin (ED₅₀ = 28.93 mg/kg) in a mouse model of systemic MRSA infection. …”

Discovery of Novel Coumarin Pleuromutilin Derivatives as Potent Anti-MRSA Agents by Kai Liu (159026)

“…Compound <b>14b</b> displayed particularly rapid bactericidal effects, slow resistance development, and low cytotoxicity. Moreover, it decreased bacterial loads in the lung, liver, kidney, spleen, and heart and exhibited better antibacterial efficacy (ED₅₀ = 11.16 mg/kg) than tiamulin (ED₅₀ = 28.93 mg/kg) in a mouse model of systemic MRSA infection. …”

Discovery of Novel Coumarin Pleuromutilin Derivatives as Potent Anti-MRSA Agents by Kai Liu (159026)

“…Compound <b>14b</b> displayed particularly rapid bactericidal effects, slow resistance development, and low cytotoxicity. Moreover, it decreased bacterial loads in the lung, liver, kidney, spleen, and heart and exhibited better antibacterial efficacy (ED₅₀ = 11.16 mg/kg) than tiamulin (ED₅₀ = 28.93 mg/kg) in a mouse model of systemic MRSA infection. …”

Reduction of thymic weight and size in rats administered cocaine. by Kana Unuma (283272)

Increased levels of PPARγ as well as adiponectin in thymus from rats administered cocaine for 14 days. by Kana Unuma (283272)

Reduction of thymic weight and size as well as ectopic development of adipocytes in thymus from rats administered cocaine for 14 days. by Kana Unuma (283272)

Downregulation of TRIM37 expression exacerbates pathological damage in the MS model. by Lai Jiang (2401513)

“…Scale bar = 50 μm. (h) qRT-PCR (n = 6) and <b>(i, j)</b> Western blot (n = 3) both showed a significant decrease in the <i>TRIM37</i> mRNA and protein levels in the LPC-induced MS model compared to the control group. * <i><i>P</i></i> < 0.05, ** <i><i>P</i></i> < 0.01, *** <i><i>P</i></i> < 0.001, **** <i><i>P</i></i> < 0.0001, ns = not significant.…”

Flux Growth and Magnetoresistance Behavior of Rare Earth Zintl Phase EuMgSn by Xiaowei Ma (113432)

Subjects:

Ustekinumab trough concentration are shown by responder status and anti-ustekinumab antibody (A) Patients with negative anti-ustekinumab antibody had significantly higher drug trou... by Hsien-Yi Chiu (799936)

C5a concentration throughout the study period. by Dzenita Smailhodzic (659524)

Trend of temperature decrease in thermogradient freezer during the night from 7:00 P.M. to 5:00 A.M. by Alireza Hasanfard (13919335)

Changes in baseline T-cell exhaustion, monocyte activation and platelet activation markers through week 12 and week 24 according to the linear regression model. a. by Tosi M. Mwakyandile (16408705)

Propofol induced cell death and decreased mitochondrial membrane potential in a concentration- and time-dependent manner. by Chisato Sumi (3521705)

Exposure to IQ3A compounds decreases <i>HSP90</i> and <i>KRAS</i> mRNA, protein expression and <i>KRAS</i> transcription. by Hugo Brito (747224)

Spatial pattern of total Cd concentration in the soils in the PRD area (mg kg⁻¹, DW). by Huihua Zhang (633008)

Decreased oscillatory flow decreases <i>klf2a</i> expression. by Julien Vermot (257990)

“…<p>(A) RFF is decreased by alterations in heart rate. …”

Surface morphologies of the Mg stent and mass loss rates. by Jeon Min Kang (12635649)

A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”

Dasatinib plasma pharmacokinetics in male and female VD₃ sufficient and deficient mice after a single oral gavage of 10 mg/kg dasatinib. by Kavya Annu (11587215)