Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 72h from 2.5 nM to 50 nM with siRNA TMPRSS2-ERG III, siRNA TMPRSS2-ERG IV or siRNA Control. …”

List of mRNAs that are differentially expressed in both the RNAPII ChIP-seq and RNA-seq datasets, mRNAs with decreased expression in both lists, and mRNAs that have decreased expre... by Katherine I. Farley-Barnes (9258036)

“…<p>List of mRNAs that are differentially expressed in both the RNAPII ChIP-seq and RNA-seq datasets, mRNAs with decreased expression in both lists, and mRNAs that have decreased expression in both lists and are also nucleolar in at least 1 database [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref050" target="_blank">50</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref052" target="_blank">52</a>].…”

Summary of cell-based assay EC50 results for WT BMP9 and A347E variant. by Tobias G. Schips (21799838)

BMS-754807 decreases AKT phosphorylation in DIPG cell-lines cultured in serum-free media. by Kyle G. Halvorson (699837)

Decrease in proliferation after ENU-exposure as decrease in BrdU immunostaining. by Vivian Capilla-Gonzalez (336046)

“…<p>Micrograph of the BrdU+ cells immunolabeled with DAB showed a decrease in the proliferation in the SVZ (B) and DG (D) of treated animals, compared with control group (A and C, respectively). …”

Klf5 down-regulation leads to human VSMC senescence. by Dong Ma (584680)

Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)

Effects of GM-CSF on the DMN-induced inhibition of PPAR-γ expression. by Mrigendra Bir Karmacharya (13607415)

Effects of GM-CSF on DMN-induced TGF-β1 expression. by Mrigendra Bir Karmacharya (13607415)

The number of Brn3a-expressing cells in retino-collicular co-cultures decreases between DIV4 and DIV12. by Sylvie Voyatzis (332702)

“…(B, C) The density of cells immunoreactive for Brn3a undergoes a reduction of ∼68% between DIV4 and DIV7, and a further decrease of ∼22% between DIV 7 and DIV12. …”

Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling by Megan Leander (459603)

“…Further, these motifs were present in red flour beetle, common water flea, honey bee, domestic silkworm, and termite MS-Rs. RhpMS and DrmMS decreased <i>R</i>. <i>prolixus</i> cardiac contractility dose dependently with EC₅₀ values of 140 nM and 50 nM. …”

Table1_Comprehensive Analysis of Expression and Prognostic Value of MS4As in Glioma.DOCX by Yingying Zeng (2122864)

Image1_Comprehensive Analysis of Expression and Prognostic Value of MS4As in Glioma.TIFF by Yingying Zeng (2122864)

Growth curves (A, strain AWRI R2 (A); B, strain BH8 (B); C, strain Freddo (F)) and accumulated fermentation system mass loss(D, strain A; E, strain B; F, strain F) of <i>S</i>. <i>... by Xiang-yu Sun (748032)

Mitochondrial protein acetylation correlates with a decrease in sirtuin 3 levels. by Mercedes García-Roche (6459200)

Increased expression of Fz5 receptor matched with a decrease in NeuN immunoreactivity at 16w. by Carlos González-Fernández (2794207)

Schematic representation of the effects of stepwise bromination of the benzene ring of benzotriazole (Bt), including interdependence of the molecular volume (A) and pK_a (B) of the products with their IC₅₀ for inhibition of protein kinase CK2α: (a) Green arrows follow sequential bromination of the central vicinal C(5)/C(6) atoms, leading to a moderate decrease of pK_a and a large decrease in IC₅₀; (b) Red arrows illustrate the lesser effects of bromination of the peripheral C(4)/C(7) atoms, resulting in a significant decrease of pK_a, with virtually no gain in inhibitory activity; (c) Black lines link products with the same number of bromine atoms, but substantially differing in pK_a and IC₅₀, culminating in the di- and tri-brominated derivatives with inhibitory activities comparable to that of TBBt. by Romualda Wąsik (119538)

Fig 2 - by Masaru Sakai (1669627)

S100A9 treatment decreases the secretion of pro-inflammatory cytokines (A) 5 days after LPS injection, sera were collected and tested for IL-6 by ELISA. by Annabelle Cesaro (112070)